Gdf7 (NM_013527) Mouse Untagged Clone

CAT#: MC216051

Gdf7 (untagged) - Mouse growth differentiation factor 7 (Gdf7), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gdf7
• Synonyms: BMP12
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC216051 representing NM_013527
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACCTGAGCGCTGCCGCCGCGCTGTGTCTCTGGCTGCTGAGCGCTTGCCGTCCCCGCGACGGGCTAG
  AAGCTGCCGCGGTGCTCCGAGCGGCGGGGGCTGGACCAGCCTGGAGCCCCGGGGGCGGCGGCGGCGGGCG
  GACCCTCGCCCGGGCTCCAGGCCCTTCAGCTCTCCAGGCCGCTGCGGTTCCGGGTCCCCGAGCTGTGCGC
  CGCGCTGCGGGTTCTGGCTTCAGGAACGGCTCGGTGGTGCCACACCACTTCATGATGTCGCTTTACAGGA
  GCCTGGCGGGGAGGGCTCCGGTCGCGGCAGCTTCAGGGCACGGGCGTGTGGACACAATCACCGGCTTCAC
  AGACCAAGCAACTCAAGGCCAGAGCTTCCTGTTCGACGTATCCAGCCTCTCCGAAGCCGATGAGGTGGTG
  AATGCGGAGCTGCGCGTGCTGCGCCGGAGGTCTCCGGAACCAGACAGGGACAGTGCGACCCTCCTTCCGC
  GGCTGCTGCTGTCCACGTGCCCGGACGAGGCTGGCACAGCTCACCTGCTGCACTCCCGGGCCGCCGAGCC
  CCTGGGCGGCGCGCGCTGGGAAGCGTTCGACGTGACGGACGCGGTGCAGAGCCACCGCCGCTGGCCGCGA
  GCCTCCCGCAAGTTCTGCCTGGTGCTGCGCGCGGTGACGGCCTCGGAGAGCAGCCCGCTGGCCCTGAGAC
  GACTGGGCTTCGGCTGGCCGGGCGGTGGCGACGGCGGCGGCACTGCGGCCGAGGAGCGCGCGCTGTTGGT
  GATCTCCTCCCGTACGCAAAGGAAAGAGAGTCTGTTCCGGGAGATCCGAGCCCAGGCCCGTGCTCTCCGG
  GCCGCTGCAGAGCCGCCACCGGATCCAGGACCAGGCGCTGGGTCACGCAAAGCCAACCTGGGCGGTCGCA
  GGCGGCGGCGGACTGCGCTGGCTGGGACTCGGGGAGCGCAGGGAAGCGGTGGTGGCGGCGGTGGCGGTGG
  CGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGCAGGCAGGGGCCACGGGCGCAGAGGCCGGAGC
  CGCTGCAGTCGCAAGTCACTGCACGTGGACTTTAAGGAGCTGGGCTGGGACGACTGGATCATCGCGCCAT
  TAGACTACGAGGCATACCACTGCGAGGGCGTTTGCGACTTTCCTCTGCGCTCGCACCTGGAGCCTACCAA
  CCACGCCATCATTCAGACGCTGCTCAACTCCATGGCGCCCGACGCTGCGCCAGCCTCCTGCTGCGTGCCC
  GCAAGGCTCAGTCCCATCAGCATTCTCTACATCGATGCCGCCAACAACGTGGTCTACAAGCAGTACGAAG
  ACATGGTGGTGGAGGCCTGCGGCTGCAGGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_013527
• ORF Size: 1362 bp
• Insert Size: 1362
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_013527.1, NP_038555.1
• RefSeq Size: 1399
• RefSeq ORF: 1362
• Locus ID: 238057
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. Mice lacking a functional copy of this gene exhibit absence of some spinal dopaminergic neurons and brain defects, male sterility, and premature death. [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.