Mmp12 (NM_008605) Mouse Untagged Clone

CAT#: MC216411

Mmp12 (untagged) - Mouse matrix metallopeptidase 12 (Mmp12), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mmp12
• Synonyms: AV378681; MME; Mmel
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC216411 representing NM_008605
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCTGCACTCTGCTGAAAGGAGTCTGCACAATGAAATTTCTCATGATGATTGTGTTCTTACAGGTAT
  CTGCCTGTGGGGCTGCTCCCATGAATGACAGTGAATTTGCTGAATGGTACTTGTCAAGATTTTATGATTA
  TGGAAAGGACAGAATTCCAATGACAAAAACAAAAACCAATAGAAACTTCCTAAAAGAAAAACTCCAGGAA
  ATGCAGCAGTTCTTTGGGCTAGAAGCAACTGGGCAACTGGACAACTCAACTCTGGCAATAATGCACATCC
  CTCGATGTGGAGTGCCCGATGTACAGCATCTTAGAGCAGTGCCCCAGAGGTCAAGATGGATGAAGCGGTA
  CCTCACTTACAGGATCTATAATTACACTCCGGACATGAAGCGTGAGGATGTAGACTACATATTTCAGAAA
  GCTTTCCAAGTCTGGAGTGATGTGACTCCTCTAAGATTCAGAAAGCTTCATAAAGATGAGGCTGACATTA
  TGATACTTTTTGCATTTGGAGCTCACGGAGACTTCAACTATTTTGATGGCAAAGGTGGTACACTAGCCCA
  TGCTTTTTATCCTGGACCTGGTATTCAAGGAGATGCACATTTTGATGAGGCAGAAACGTGGACTAAAAGT
  TTTCAAGGCACAAACCTCTTCCTTGTTGCTGTTCATGAACTTGGCCATTCCTTGGGGCTGCAGCATTCCA
  ATAATCCAAAGTCAATAATGTACCCCACCTACAGATACCTTAACCCCAGCACATTTCGCCTCTCTGCTGA
  TGACATACGTAACATTCAGTCCCTCTATGGAGCCCCAGTGAAACCCCCATCCTTGACAAAACCTAGCAGT
  CCACCATCAACTTTCTGTCACCAAAGCTTGAGTTTTGATGCTGTCACAACAGTGGGAGAGAAAATCTTTT
  TCTTTAAAGACTGGTTCTTCTGGTGGAAGCTTCCTGGGAGTCCAGCCACCAACATTACTTCTATTTCTTC
  CATATGGCCAAGCATCCCATCTGGTATTCAAGCTGCTTACGAAATTGAAAGCAGAAATCAACTTTTCCTT
  TTTAAAGATGAGAAGTACTGGTTAATAAACAACTTAGTACCAGAGCCACACTATCCCAGGAGCATATATT
  CCCTGGGCTTCTCTGCATCTGTGAAGAAGGTTGATGCAGCTGTCTTTGACCCACTTCGCCAAAAGGTTTA
  TTTCTTTGTGGATAAACACTACTGGAGGTATGATGTGAGGCAGGAGCTCATGGACCCTGCTTACCCCAAG
  CTGATTTCCACACACTTCCCAGGAATCAAGCCTAAAATTGATGCAGTCCTCTATTTCAAAAGACACTACT
  ACATCTTCCAAGGAGCCTATCAATTGGAATATGACCCCCTGTTCCGTCGTGTCACCAAAACATTGAAAAG
  TACAAGCTGGTTTGGTTGTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008605
• ORF Size: 1422 bp
• Insert Size: 1422
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_008605.3, NP_032631.3
• RefSeq Size: 3607
• RefSeq ORF: 1422
• Locus ID: 17381
• Gene Summary: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein have a diminished capacity to degrade extracellular matrix components, do not develop emphysema in response to long-term exposure to cigarette smoke, and exhibit impaired clearance and increased mortality upon bacterial infection. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (1).