Bace2 (NM_019517) Mouse Untagged Clone

CAT#: MC217304

Bace2 (untagged) - Mouse beta-site APP-cleaving enzyme 2 (Bace2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bace2
• Synonyms: 1110059C24Rik; AEPLC; AI850424; ALP56; ARP1; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC217304 representing NM_019517
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCGCGCTGCTTCGAGCACTCTTGCTCCCGGTGCTGGCGCAGTGGCTCTTGAGTGCGGTCCCCGCGC
  TGGCCCCCGCGCCCTTCACGCTGCCCCTCCAAGTGGCCCGGGCCACGAACCACAGAGCCTCGGCTGTTCC
  CGGACTCGGGACCCCCGAGTTGCCCCGGGCCGATGGTCTGGCCCTCGCACTGGAGCCTGTCAGGGCTACT
  GCCAACTTCTTGGCTATGGTGGACAACCTTCAGGGGGACTCTGGCCGCGGCTACTACCTAGAGATGCTGA
  TCGGGACCCCTCCGCAGAAGGTACAGATTCTTGTGGACACTGGAAGCAGTAACTTCGCTGTGGCAGGTGC
  CCCACACTCCTACATAGACACCTACTTTGACTCAGAGAGCTCCAGCACATACCACTCCAAGGGCTTTGAT
  GTCACTGTGAAGTACACACAGGGAAGCTGGACTGGCTTTGTTGGTGAGGACCTTGTCACCATCCCAAAAG
  GCTTCAACAGCTCTTTCTTGGTCAATATTGCCACTATTTTCGAGTCTGAGAATTTCTTTTTGCCTGGTAT
  TAAATGGAATGGAATCCTTGGACTTGCTTATGCTGCTTTGGCCAAGCCATCAAGCTCTCTGGAGACATTT
  TTTGATTCCCTGGTGGCCCAAGCAAAGATTCCAGACATTTTCTCCATGCAGATGTGCGGGGCTGGATTGC
  CAGTAGCTGGTTCTGGTACCAACGGAGGTAGTCTTGTCCTGGGTGGGATTGAACCAAGTTTGTATAAAGG
  AGATATCTGGTATACCCCAATTAAAGAGGAATGGTACTATCAAATAGAAATCCTGAAGTTGGAAATTGGA
  GGCCAGAACCTCAACCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATTGTGGACAGTGGCACCACGC
  TCCTGCGCCTGCCCCAGAAGGTGTTTGATGCAGTGGTGGAAGCTGTGGCACGAACATCTCTGATTCCAGA
  GTTTTCTGATGGCTTCTGGACAGGGGCCCAGCTGGCATGCTGGACAAATTCTGAAACGCCATGGGCATAT
  TTCCCTAAGATTTCTATCTACCTGAGAGATGAGAATGCCAGTCGCTCCTTCCGGATCACCATTCTCCCAC
  AGCTCTACATTCAGCCCATGATGGGAGCTGGTTTCAATTATGAATGCTACCGTTTTGGTATCTCCTCTTC
  CACAAATGCGCTGGTGATTGGTGCGACCGTGATGGAAGGCTTCTACGTGGTCTTTGACAGAGCTCAGAGG
  AGGGTGGGCTTTGCAGTGAGTCCCTGTGCAGAGATTGAAGGTACCACAGTGTCTGAAATTTCTGGGCCCT
  TTTCCACGGAAGACATAGCCAGCAACTGTGTTCCAGCACAGGCTCTGAATGAGCCCATCTTGTGGATTGT
  GTCCTATGCCCTGATGAGTGTGTGTGGAGCCATTCTCCTGGTTCTGATCCTCCTCCTGCTGCTCCCGCTG
  CACTGCCGTCATGCCCCCCGAGACCCTGAGGTAGTTAACGATGAGTCCTCACTAGTCAGACATCGCTGGA
  AATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_019517
• ORF Size: 1545 bp
• Insert Size: 1545
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_019517.5, NP_062390.3
• RefSeq Size: 7686
• RefSeq ORF: 1545
• Locus ID: 56175
• Gene Summary: This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein undergoes proteolytic processing to generate an active endopeptidase enzyme. This transmembrane protease catalyzes the proteolysis of amyloid precursor protein to produce amyloid beta peptide. Mice lacking the encoded product exhibit increased pancreatic beta cell mass and improved glucose tolerance due to increased insulin secretion. [provided by RefSeq, Jul 2016]