Fance (NM_001163819) Mouse Untagged Clone

CAT#: MC217474

Fance (untagged) - Mouse Fanconi anemia, complementation group E (Fance), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fance
• Synonyms: 2810451D06Rik; AI415634; AW209126
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC217474 representing NM_001163819
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  CTGGCGACGCCGGGGTCGGACTCCGTAGCCTCGGCCGGAGCGGCGCCCTGGGCGAGCCTGGAGGCCCCTG
  CCCGCCTCCTGCTTCAGGCGCTACAGGCAGGGCCTGAGGGTGCGCGGCGCGGGCTAGGGGTTCTGCGCGC
  CCTCGGCCGCCGCGCGGAGCACTTCCCTTGGGATGGCTTCCTGGAGGCGCTGGGCCACTTAGAGCCCGAG
  GTGCGGGGCCCCGACGGCCGCCTAGAGCTGGTCCCACTGTTGCTCCGGCTGCCTGGGGTCTGCCAGAAGA
  ACCTGCTGTCCCTGCTGCTGGCTCTCCTACCATCCTTACCTGAAAGCGGACTCCGCTCTGTGCTGCAGCT
  CCACCATCAGGATGTGTCCTCTACCACTGATGCCTGGCTCCATGCCCTGGGGGAGCTGCTGCGAAGGGAT
  GTGGGGGTTGGAGTCGCTGAGGGATCTTCTCCATTGACCAGAAGCTGTCAGTTACAGCTCCGGGACCTGT
  GTGGGCGGCTGGGCCAAGGGGGGAGGGGGCTGAAACTGGCCCTGGCTCCAGATCCTGAACAAGAGGACAG
  ACTCTCACAGCTTTGCGGGAAACGGACGAAAGAGCCAGAAGAGGCTGCCAGCCCTGAGTCAGAGAGATCC
  CCTAAAAGGTTCCGGGGCTGTGAGGAGGCGGTGGAAGGAAAGGAACCGGAGGAGAGACCCACGCTGGAGT
  CGCTGGGATCCCCACCAGATGCAGGAGGCGTGTTGCCTGACACTGACGCCCAGGCTCCGGAGACTGGCCC
  TGGCGTGGAGGGTCCCAAGGGTCCCGCTGAGAGTGTGGAGTTGCCCAAAGTTGTCCAGGACCAGGTGCCC
  AGGCTGCAGCTGCTGCTGAAGGCCTTCCAGGAGGGGCTGGAGGGTCAGGAGAAGCCCCTAGTGGACCTGC
  AGTTTCTTCATGAATGTAGTCCCAGCGAGATGGAGTTGCTATGCAGCGAACTACAGCTACCCCAGCTCCC
  TGACGGAGGTCTCCTGCAGCTCTGCAGCCACCTGATGGGTCTCACACCAGCCCTCAGCCTCAGCAATGCC
  TCTGTGCTGGCCAGGAGCCTCTTTCTTGACCGGATCCGCTCCCTGCCGTCTTCTGCCTCCAGGCTTCTCA
  GAGTGGCCCTCGTCTCCTTCTGTGTAAAGTACACCTACGCCATCTGCAGGGCTGTCCTCTGTCCCTTGCT
  CCAGGACCCTCGTGTAGGTCCTGCGCAGACCGAGTTACTGTGTTCCCTCATAAAGGATGAGTCCCTGGAG
  TCAGACATGCAGGTCCAGATTTTGGGGCAGGTCCTGGAGCTGGCCTGGCGAGAAGAGACGTTCCTGGTGT
  TGCAGACGCTCCTGGAACGGCAGGTAGAGATGACCCCTGAGGTGTTCAGTGTCTTAGTGCAGAGGCTCTG
  CAAAGAGGGACCAGCAGCCACTACCTCCATGGCCTATGCCAAGCTGATGCTGACGGTGATGACCAAGTAC
  CAGACCAGTATCACAGAGCAGCAGAGCCTGGACCTGGCTGTGGCCCTAGAGCCCAACGCCACCTTCCTGA
  AGAAGGCCCTGCAAGCAGCGCTGAGACATGTGACCCACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001163819
• ORF Size: 1581 bp
• Insert Size: 1581
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001163819.1, NP_001157291.1
• RefSeq Size: 2016
• RefSeq ORF: 1581
• Locus ID: 72775
• Gene Summary: This gene encodes the complementation group E subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes: FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The FA complex is necessary for protection against DNA damage. This gene product is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2. Defects in the related human gene are a cause of Fanconi anemia, a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Translation of this protein is initiated at a non-AUG (CUG) start codon, which is inferred from the related human gene and the notion that this protein is functionally indispensable. Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. The combination of alternatively spliced exons within the coding region and the non-AUG start codon (CUG at nt 115) are inferred based on available transcript data, and further supported by similar exon-intron structure of the orthologous human gene (GeneID:2178) that encodes a functionally important protein.