Dao (NM_001286397) Mouse Untagged Clone

CAT#: MC226563

Dao (untagged) - Mouse D-amino acid oxidase (Dao), transcript variant 3

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dao
• Synonyms: AI987963; DAAO; DAMOX; Dao-1; Dao1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC226563 representing NM_001286397
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGCGTGGCCGTGATCGGAGCAGGAGTCATTGGGCTCTCCACAGCCCTCTGCATTCATGAGCGTTACC
  ACCCAACACAGCCACTGCACATGAAGATCTATGCAGATCGATTCACCCCGTTCACCACGAGCGATGTGGC
  CGCCGGCCTCTGGCAGCCTTATCTCTCTGACCCCAGCAACCCTCAGGAGGCGGAGTGGAGCCAGCAAACG
  TTTGATTACCTGCTGAGCTGCCTCCATTCTCCAAACGCTGAAAAAATGGGCCTGGCCCTAATCTCAGGCT
  ACAACCTCTTCCGAGATGAAGTTCCGGACCCTTTCTGGAAAAACGCAGTTCTGGGATTCCGGAAGCTGAC
  CCCCAGTGAGATGGACCTGTTCCCTGATTATGGCTACGGCTGGTTCAATACAAGCCTCCTTCTAGAGGGG
  AAGAGCTACCTGCCATGGCTAACTGAGAGGTTAACTGAGAGGGGAGTGAAGCTTATCCATCGGAAGGTGG
  AGTCTCTCGAAGAGGTGGCAAGAGGAGTGGATGTGATTATCAACTGCACCGGGGTGTGGGCCGGGGCCCT
  GCAAGCAGATGCCTCCCTGCAGCCAGGCCGGGGCCAGATCATCCAGGTGGAGGCCCCTTGGATTAAACAC
  TTCATCCTCACCCATGATCCTAGCCTTGGTATCTACAACTCTCCGTACATCATCCCAGGAATGCAAGAAT
  TGTGGGTGAACTCACTGGCTTCCGGCCAGTCCGGCCTCAGGTCCGGCTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001286397
• ORF Size: 750 bp
• Insert Size: 750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001286397.1, NP_001273326.1
• RefSeq Size: 1751
• RefSeq ORF: 750
• Locus ID: 13142
• Gene Summary: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (3) lacks an alternate exon in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.