Uros (NM_001302085) Mouse Untagged Clone

CAT#: MC226675

Uros (untagged) - Mouse uroporphyrinogen III synthase (Uros), transcript variant 1

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Uros
• Synonyms: AI415298; UROIIIS; Uros3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC226675 representing NM_001302085
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGGTTCTCTTACTAAAAGACGCCAAGGAGGATGACAGCGGCCTGGATCCATATATCCAGGAGCTGC
  GATTGTGTGGCCTAGAAGCCACACTGATTCCTGTGCTGTCATTTGAGTTTATGTCTCTCCCCAGTTTGTC
  AGAAAAGCTGTCTCATCCTGAAGGCTTTGGAGGACTCATTTTCACCAGCCCCAGGGCAGTGGAAGCAGTG
  AAGCTGTGTTTGGAGAAGGACAATAAAACTGAAGCCTGGGAGAAGTCTCTGAAAGACAGATGGAATGCCA
  AGTCTGTGTACGTGGTTGGAAGTGCCACCGCTTCTCTAGTGAATAAAATTGGTCTGGATGCAGAAGGAGC
  GGGCAGTGGAAATGCAGAAAAGCTTGCTGAATATATTTGCTCAAAGCCATCTTCAGAGCTGCCTCTTCTC
  TTTCCGTGTGGAACTATCAAAGGAGATACTCTTCCAAAAATGCTCAAGGACAAAGGGATCCCCATGGAAA
  GCATGCATGTCTATCAGACAGTTCCACACCCTGGGATCCAAGGGAGCCTGAAGAGCTACTATGAAGATCA
  GGGTATCCCAGCCAGCATCACGTTTTTCAGTCCCTCCGGCCTTAAATACAGCCTCGAGTATATTCAGGCG
  TTATCTGGCAGCAGCTTTGACCAGATTAAGTTTATAGCCATTGGCCCCAGTACAACCCGTGCTATGGCTG
  CTAAGGGCCTGCCTGTGAGCTGCACTGCAGAGAGCCCCACACCACAAGCCCTGGCTGCAGGCATCAGGAA
  TGTGCTGAAGCCAAACCACTGTTGCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001302085
• ORF Size: 798 bp
• Insert Size: 798
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001302085.1, NP_001289014.1
• RefSeq Size: 1887
• RefSeq ORF: 798
• Locus ID: 22276
• Gene Summary: The protein encoded by this gene is the fourth enzyme in the heme biosynthesis pathway. It converts hydroxymethylbilane to uroporphyrinogen III, a cyclic tetrapyrrole. This enzyme is defective in the autosomal recessive disorder congenital erythropoietic porphyria. Alternate promoter usage controls cell type-specific expression, including erythroid cell-specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2, 4, and 5 all encode the same isoform (1).