Tpm2 (NM_001277875) Mouse Untagged Clone

CAT#: MC226788

Tpm2 (untagged) - Mouse tropomyosin 2, beta (Tpm2), transcript variant Tpm2.3

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tpm2
• Synonyms: Tpm-2; Trop-2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC226788 representing NM_001277875
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGCCATCAAGAAGAAGATGCAGATGCTGAAACTGGACAAGGAGAATGCCATCGACCGCGCGGAGC
  AGGCCGAAGCCGACAAAAAGCAAGCTGAAGACCGATGCAAGCAGCTGGAGGAAGAGCAGCAGGCCCTCCA
  GAAGAAGCTGAAGGGGACAGAGGACGAGGTGGAAAAGTATTCCGAGTCCGTGAAGGATGCCCAGGAGAAA
  CTGGAGCAGGCTGAGAAGAAGGCCACCGACGCTGAAGCAGATGTGGCCTCTCTGAACCGCCGCATTCAGC
  TCGTAGAGGAGGAGTTGGATCGGGCACAGGAGCGCCTGGCTACAGCCTTGCAAAAGCTGGAGGAGGCTGA
  GAAAGCCGCGGATGAGAGCGAGAGAGGAATGAAGGTCATTGAAAACCGGGCCATGAAGGATGAGGAAAAG
  ATGGAGCTGCAGGAGATGCAGCTGAAGGAAGCCAAGCACATCGCTGAGGACTCAGACCGCAAATATGAGG
  AGGTGGCCAGGAAGCTGGTGATCCTGGAAGGGGAGCTGGAGCGCTCGGAAGAGAGAGCCGAGGTGGCTGA
  GAGTAAATGTGGGGACCTAGAGGAGGAGCTGAAAATTGTTACCAACAACTTGAAATCCCTGGAAGCCCAA
  GCGGACAAGTATTCCACCAAAGAGGACAAATACGAAGAAGAGATCAAACTTCTGGAGGAGAAGCTGAAAG
  AGGCTGAGACCCGAGCAGAGTTTGCTGAAAGATCTGTGGCAAAGTTGGAGAAAACCATTGATGATCTGGA
  AGAGACTTTGGCCAGTGCCAAGGAAGAGAACGTGGAGATACACCAGACCTTGGACCAGACCCTTCTGGAA
  CTCAACAACCTGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001277875
• ORF Size: 855 bp
• Insert Size: 855
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001277875.1, NP_001264804.1
• RefSeq Size: 2108
• RefSeq ORF: 855
• Locus ID: 22004
• Gene Summary: This gene belongs to the tropomyosin family which encodes proteins that bind to actin filaments and stabilize them by regulating access to actin modifying proteins. The encoded protein is a high molecular weight tropomyosin expressed in slow skeletal muscle. In humans, mutations in this gene are associated with nemaline myopathy, cap disease and distal arthrogryposis syndromes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]
  Transcript Variant: This variant (Tpm2.3, also known as variant 2) uses an alternate splice site in the 3' coding region, compared to variant Tpm2.2. It encodes isoform Tpm2.3 (also known as isoform 2) which is of the same size, but has a distinct C-terminus, compared to isoform Tpm2.2st.