Casp9 (NM_001277932) Mouse Untagged Clone

CAT#: MC227532

Casp9 (untagged) - Mouse caspase 9 (Casp9), transcript variant 2

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Casp9
• Synonyms: AI115399; APAF-3; AW493809; CASP-9; Caspase-9; ICE-LAP6; Mch6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC227532 representing NM_001277932
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGAGGCGGACCGGCAGCTCCTGCGGCGATGCAGGGTGCGCCTAGTGAGCGAGCTGCAAGTCGCGG
  AGCTCTGGGACGCTCTGCTGAGTCGAGAGCTCTTCACGCGCGACATGATCGAGGATATTCAGCAGGCAGG
  ATCTGGGTCTCGGCGGGATCAGGCCAGGCAGCTGGTCACAGACCTTGAGACCCGAGGGAGGCAGGCCCTT
  CCTCTCTTCATCTCCTGCTTAGAGGACACAGGCCAAGGCACCCTGGCTTCACTCTTGCAAAGCGGTCGGC
  AAGCAGCCAAGCAGGATCCAGAGGCTGTTAAACCCCTAGACCACCTGGTGCCTGTGGTCCTGGGACCAAT
  GGGACTCACAGCAAAGGAGCAGAGAGTAGTGAAGCTGGACCCGTCACAGCCTGCCGTGGGAAACCTCACC
  CCAGTGGTGCTGGGGCCAGAAGAGCTCTGGCCTGCTCGGCTCAAGCCAGAGGTTCTCAGACCAGAAACAC
  CCAGGCCCGTGGACATTGGTTCTGGCGGAGCTCATGATGTCTGTGTTCCAGGGAAGATCAGGGGACATGC
  AGATATGGCATACACCCTGGATTCGGATCCCTGTGGCCACTGCCTCATCATCAACAATGTGAACTTCTGC
  CCTTCCTCGGGGCTCGGCACACGCACGGGCTCCAACTTGGACCGTGACAAACTTGAGCACCGATTCCGCT
  GGCTGCGCTTCATGGTGGAGGTGAAGAACGACCTGACTGCCAAGAAAATGGTCACGGCTTTGATGGAGAT
  GGCACACCGGAACCACCGTGCCCTGGACTGCTTTGTGGTGGTCATCCTCTCTCATGGCTGCCAGGCCAGC
  CACCTCCAGTTCCCGGGTGCTGTCTATGGGACAGATGGATGCTCCGTGTCCATTGAGAAAATTGTGAATA
  TCTTCAACGGGAGCGGCTGCCCCAGCCTGGGAGGGAAGCCCAAGCTCTTCTTCATCCAGGCCTGCGGTGG
  TGAGCAGAAAGACCATGGCTTTGAGGTGGCCTGCACTTCCTCTCAAGGCAGGACCTTGGACAGTGACTCT
  GAGCCAGATGCTGTCCCCTATCAGGAAGGCCCAAGGCCCTTGGACCAGCTGGATGCTGTGTCAAGTTTGC
  CTACCCCCAGTGACATCCTTGTGTCCTACTCCACCTTCCCAGGTTGCCAATGCTGTTTCTGCGAAAGGGA
  CTTACAAGCAGATTCCTGGCTGTTTTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001277932
• ORF Size: 1218 bp
• Insert Size: 1218
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001277932.1, NP_001264861.1
• RefSeq Size: 3789
• RefSeq ORF: 1218
• Locus ID: 12371
• Gene Summary: This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, the initiator caspase, is activated after cytochrome c release from mitochondria and targets downstream effectors. In mouse, deficiency of this gene can cause perinatal lethality. This protein may have a role in normal brain development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013]
  Transcript Variant: This variant (2) lacks an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.