Dclre1c (NM_001302684) Mouse Untagged Clone

CAT#: MC228345

Dclre1c (untagged) - Mouse DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) (Dclre1c), transcript variant 5

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dclre1c
• Synonyms: 9930121L06Rik; AI661365; Art; Snm1l
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC228345 representing NM_001302684
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCTCCTTCCAGGGACAGATGGCGGAGTATCCAACCATCTCCATTGACCGCTTCGACAGGGAGAACC
  TGAAAGCCCGTGCCTACTTCCTTTCGCACTGTCACAAGGATCACATGAAAGGATTAAGGGCTCCTTCCTT
  GAAAAGAAGGCTGGAATGCAGCTTGAAGGTCTTCCTGTACTGTTCTCCAGTCACTAAGGAGCTGTTGTTA
  ACTAGCCCAAAGTACAGATTCTGGGAAAACAGAATTATAACAATTGAAATTGAAACTCCTACGCAGATAT
  CTTTAGTTGATGAGGCTTCGGGTGAGAAGGAAGAGGTTGTTGTGACTCTCTTACCAGCTGGTCACTGCCC
  AGGATCAGTTATGTTTTTATTTCAGGGCAGTAATGGAACTGTCTTATACACAGGAGACTTCAGACTGGCA
  AAAGGAGAAGCTTCCAGAATGGAGCTTCTGCACTCTGGAGGCAGAGTAAAAGACATCCAAAGTGTGTATT
  TAGACACGACTTTCTGTGACCCAAGGTTTTATCAGATCCCAAGTCGTGAGCAGTGTTTGAGGGGCATTTT
  GGAGCTGGTTCGGAGCTGGGTCACTAGGAGTCCGCACCACGTCGTGTGGCTGAACTGTAAAGCAGCTTAT
  GGCTACGAGTATTTATTCACCAACCTAAGCGAGGAGCTGGGAGTTCAGGTTCATGTGGACAAGCTGGACA
  TGTTTAAAAACATGCCTGATATCCTGCACCATCTCACAACGGACAGAAACACCCAGATCCACGCCTGCCG
  CCACCCAAAGGCAGAAGAGTGTTTTCAGTGGAATAAACTACCCTGTGGTATAACTTCCCAAAACAAAACT
  GCACTCCACACAATCAGCATCAAGCCATCTACCATGTGGTTTGGAGAGAGGACCAGAAAAACCAACGTGA
  TCGTTAGGACTGGAGAGAGCTCATACAGAGCTTGCTTCTCTTTTCACTCCTCCTTCAGTGAGATTAAAGA
  TTTTTTGAGCTACATCTGCCCAGTGAATGTGTATCCAAATGTCATCCCAGTTGGCCTCACTGTGGATAAG
  GTCATGGACGTTTTAAAGCCTCTGTGCCGGTCTCCCCAAAGTGTTGAGCCAAAGTACAAACCGCTTGGAA
  AATTGAAGAGAGCCAGAACAATCCATCTTGACTCGGAGGAAGACGATGATCTCTTTGATGACCCTCTACC
  GACACCTTTAAGGCACAAAGTTCCGTACCAGCTAACTCTTCAGCCTGAGCTGTTTTCAATGAAGGCACTG
  CCACTAGACCAGCCTGAACTGAGACAAAGCCCAGGAGGCTGCAAAGCAGAGAGTGTGTGGAGCCCTTCTT
  TGGCTAACTTCATAGACTGTGAAGAATCCAACAGCGACAGTGGAGAAGAGCTAGAAACCCCACCACCCTC
  ACTGCAGGGAGGTCTGGGCCCCTCGACACTCGTCCAGCAAAATGCTGATCCGGATGTGGACATACCACAG
  TGGGAAGTCTTCTTCAAAAGAAGAGATGAAATCACAGAACTAGACACCCTGAGTGGCAGGAAGTCTCCAC
  CTGAGAAGACATTGCTAAGCAGCACACGTGCAGACTCACAGAGCTCCTCTGACTTTGAAATCCCCTCAAC
  TCCCGAAGCGGAGCTTCCTACGCCAGAGCATTTGCAGTGCTTATACAGGAAACTGGCAACAGGTCAAAGT
  ATAGTTGTCGAAAAAAGAAAATGTTCACTTTTAGATAGTTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001302684
• ORF Size: 1722 bp
• Insert Size: 1722
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001302684.1, NP_001289613.1
• RefSeq Size: 3363
• RefSeq ORF: 1722
• Locus ID: 227525
• Gene Summary: This gene encodes a member of the SNM1 family of nucleases and is involved in V(D)J recombination and DNA repair. This protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Homozygous knockout mice for this gene exhibit severe combined immunodeficiency with sensitivity to ionizing radiation. Mutations in this gene in humans can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2014]
  Transcript Variant: This variant (5) lacks an alternate in-frame segment in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 5), compared to isoform 1.