Timp3 (NM_011595) Mouse Tagged ORF Clone

CAT#: MG202295

Timp3 (GFP-tagged) - Mouse tissue inhibitor of metalloproteinase 3 (Timp3)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Timp3
• Synonyms: Timp-3
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG202295 representing NM_011595
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTCCCTGGCTTGGGCTTGTCGTGCTCCTGAGCTGCTGGAGCCTTGGGCACTGGGGCGCGGAAGCGT
  GCACATGCTCTCCCAGCCACAGCCAGGATGCCTTCTGCAACTCCGACATCGTGATCCGGGCCAAAGTGGT
  GGGAAAGAAGCTGGTGACGGAGGGGCCCTTTGGCACTCTGGTCTACACTATTAAGCAGATGAAGATGTAC
  CGAGGCTTCAGTAAGATGCCCCACGTGCAGTACATTCACACGGAAGCCTCTGAAAGTCTTTGTGGCCTCA
  AGCTAGAAGTCAACAAATACCAGTACCTGCTGACAGGGCGCGTGTATGAAGGCAAGATGTACACAGGACT
  GTGCAACTTTGTGGAGAGGTGGGACCACCTCACACTGTCCCAGCGCAAGGGCCTCAATTACCGCTACCAC
  CTGGGTTGCAATTGCAAGATCAATTCCTGCTACTACTTGCCTTGTTTTGTGACCTCCAAGAATGAGTGTC
  TCTGGACCGACATGCTCTCCAATTTTGGGTACCCTGGCTATCAGTCCAAACACTACGCCTGCATCCGGCA
  GAAGGGTGGCTACTGCAGCTGGTACCGAGGATGGGCTCCCCCAGACAAGAGCATCAGCAACGCCACAGAC
  CCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG202295 representing NM_011595
  Red=Cloning site Green=Tags(s)
  
  MTPWLGLVVLLSCWSLGHWGAEACTCSPSHSQDAFCNSDIVIRAKVVGKKLVTEGPFGTLVYTIKQMKMY
  RGFSKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYEGKMYTGLCNFVERWDHLTLSQRKGLNYRYH
  LGCNCKINSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSISNATD
  P
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_011595
• ORF Size: 633 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011595.2, NP_035725.1
• RefSeq Size: 4681
• RefSeq ORF: 636
• Locus ID: 21859
• Gene Summary: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. [UniProtKB/Swiss-Prot Function]