Btg3 (BC094027) Mouse Tagged ORF Clone

CAT#: MG203216

Btg3 (GFP-tagged) - Mouse B-cell translocation gene 3 (cDNA clone MGC:103173 IMAGE:4457150)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Btg3
• Synonyms: tob5, ANA
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG203216 representing BC094027
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGAACGAAATTGCGGCTGTTGTCTTCTTTTTCACAAGGCTAGTTCGAAAGCATGACAAGTTGAAAA
  AAGAAGCAGTTGAGAGGTTTGCTGAGAAATTAACTCAAATACTTCAAGAGAAATATAAAAATCACTGGTA
  TCCAGAAAAACCATCCAAAGGTCAGGCCTACAGATGCATTCGTGTCAATAAGTTTCAGAGAGTTGATCCC
  GATGTCCTGAAAGCCTGTGAGAACAGCTGCATCTTGTACAGCGACCTGGGCTTGCCTAAGGAGCTTACAC
  TCTGGGTGGATCCGTGTGAGGTGTGCTGCCGGTATGGAGAGAAAAACAATGCGTTCATTGTTGCCAGCTT
  TGAAAATGAGGACGAGAACAAGGATGAAATCTCCAAGAAAGTTAGCAGGGCTCTGGATAAGGTGACCTCT
  GATTATCACTCAGGGTCCTCTTCCTCAGATGAAGACACAAGCAAGGAAGTGGACGTGAAACCCAGCTCAG
  TGGCGGCAACACCAAGCCCCGTGTACCAGATTTCAGAACTGATATTCCCACCTCTTCCAATGTGGCACCC
  TTTGCCCAGAAAAAAGCCAGGAATGTATCGAGGGAGCGGCCATCAGACTCACTACCCTCCTCCTGTTCCA
  TTTGCTTATCCAAATCCAGGAAGGAAGAATAAACCATTCCGCCCAATTCCAGTGACATGGGTACCTCCTC
  CTGGAATGCATTGTGACCGAAATCACTGGATTAATCCTCACATGTTAGCACCTCAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG203216 representing BC094027
  Red=Cloning site Green=Tags(s)
  
  MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTQILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDP
  DVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENEDENKDEISKKVSRALDKVTS
  DYHSGSSSSDEDTSKEVDVKPSSVAATPSPVYQISELIFPPLPMWHPLPRKKPGMYRGSGHQTHYPPPVP
  FAYPNPGRKNKPFRPIPVTWVPPPGMHCDRNHWINPHMLAPH
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: BC094027
• ORF Size: 758 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: BC094027, AAH94027
• RefSeq Size: 1429
• RefSeq ORF: 758
• Locus ID: 12228
• Gene Summary: This gene encodes B cell translocation gene 3, a member of the BTG gene family. This family is defined by a conserved N-terminal domain, known to bind transcription factors, and a less conserved C-terminal domain. This protein is thought to have anti-proliferative properties, and may be involved in regulating the G1-S transition to suppress cell cycle progression. Mice deficient for this gene display an increased incidence of lung cancers, and many human lung cancer cells exhibit decreased levels of B cell translocation gene 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 17. [provided by RefSeq, Jul 2014]