Ctsz (NM_022325) Mouse Tagged ORF Clone

CAT#: MG204311

Ctsz (GFP-tagged) - Mouse cathepsin Z (Ctsz)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Ctsz
• Synonyms: AI787083; AU019819; CTSX; D2Wsu143e
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG204311 representing NM_022325
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGTCGTCGGGGTCGGTGCAGCAGCTGCCCCTGGTGCTGCTGATGTTGCTGTTGGCGAGTGCGGCAC
  GGGCCAGACTCTACTTCCGCTCGGGCCAGACTTGCTACCATCCCATTCGCGGGGACCAGCTGGCTCTGCT
  GGGGCGCAGGACTTATCCTCGGCCACATGAGTACCTGTCCCCAGCGGATCTCCCTAAGAATTGGGACTGG
  AGAAATGTGAACGGTGTCAACTATGCCAGCGTCACCAGGAACCAGCACATCCCACAGTACTGTGGTTCCT
  GCTGGGCCCACGGCAGCACCAGTGCCATGGCAGACCGAATCAACATCAAGAGGAAAGGTGCATGGCCCTC
  CATCCTGCTGTCCGTACAGAATGTCATTGACTGTGGCAATGCTGGCTCTTGTGAAGGGGGCAATGACCTT
  CCGGTGTGGGAGTATGCCCACAAGCATGGCATCCCCGATGAGACCTGCAACAACTACCAGGCCAAGGACC
  AAGACTGTGACAAGTTTAACCAGTGTGGGACCTGCACTGAATTCAAAGAGTGTCACACCATCCAGAATTA
  CACCCTCTGGAGAGTGGGTGATTACGGTTCCCTGTCCGGGAGGGAGAAGATGATGGCCGAGATCTATGCC
  AATGGTCCCATCAGCTGCGGGATAATGGCAACAGAGATGATGTCTAACTACACTGGAGGCATCTATGCTG
  AGCACCAGGACCAGGCTGTTATCAACCACATCATCTCTGTAGCTGGCTGGGGTGTCAGCAACGATGGCAT
  CGAGTACTGGATTGTCCGAAATTCATGGGGCGAACCCTGGGGTGAGAAAGGCTGGATGAGGATCGTGACC
  AGCACCTACAAGGGAGGCACAGGTGACAGCTACAACCTTGCCATCGAGAGTGCCTGCACATTTGGGGACC
  CCATTGTT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG204311 representing NM_022325
  Red=Cloning site Green=Tags(s)
  
  MASSGSVQQLPLVLLMLLLASAARARLYFRSGQTCYHPIRGDQLALLGRRTYPRPHEYLSPADLPKNWDW
  RNVNGVNYASVTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSILLSVQNVIDCGNAGSCEGGNDL
  PVWEYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYA
  NGPISCGIMATEMMSNYTGGIYAEHQDQAVINHIISVAGWGVSNDGIEYWIVRNSWGEPWGEKGWMRIVT
  STYKGGTGDSYNLAIESACTFGDPIV
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_022325
• ORF Size: 918 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022325.4, NP_071720.1
• RefSeq Size: 1393
• RefSeq ORF: 921
• Locus ID: 64138
• Gene Summary: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate a mature enzyme with carboxypeptidase activity. An enzymatically inactive form of the protein, that is associated with the propeptide, may be involved in cancer cell invasion and proliferation. Homozygous knockout mice for this gene exhibit impaired cancer cell invasion in a breast cancer model. [provided by RefSeq, Aug 2015]