Ctse (NM_007799) Mouse Tagged ORF Clone

CAT#: MG206223

Ctse (GFP-tagged) - Mouse cathepsin E (Ctse)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Ctse
• Synonyms: A430072O03Rik; C920004C08Rik; CatE; CE
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG206223 representing NM_007799
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGCCCCTCCTTGTGCTGCTGCTGCTGCTGCTCCTGGATCTGGCTCAGGCCCAAGGTGCTCTGCACA
  GAGTGCCCCTCAGAAGACATCAGTCCCTTCGGAAGAAACTACGGGCCCAAGGACAGCTCTCAGAATTCTG
  GAGGTCTCATAACTTGGACATGACCCGACTCAGCGAGTCCTGTAATGTGTATTCGAGTGTCAATGAACCC
  CTCATCAACTACCTGGATATGGAATACTTTGGCACCATCTCCATCGGCACCCCGCCGCAGAACTTCACTG
  TCATCTTTGACACCGGTTCATCCAACCTCTGGGTCCCTTCTGTGTACTGCACCAGCCCAGCATGCAAGGC
  ACACCCAGTATTCCATCCATCGCAGTCCGACACATACACGGAGGTAGGGAATCATTTCTCCATCCAGTAT
  GGTACCGGGAGCCTGACAGGAATCATTGGAGCTGATCAAGTCTCTGTGGAAGGGTTGACTGTGGATGGCC
  AGCAGTTTGGAGAAAGTGTCAAGGAGCCAGGCCAGACCTTTGTGAATGCAGAGTTTGATGGGATTCTGGG
  TCTGGGATACCCCTCATTGGCTGCTGGAGGAGTGACCCCAGTGTTTGACAACATGATGGCCCAGAACCTT
  GTGGCTCTGCCTATGTTTTCTGTCTACTTGAGCAGTGACCCTCAAGGTGGCTCAGGCAGTGAGCTGACTT
  TCGGAGGCTATGACCCCTCTCATTTCTCTGGGAGCCTCAACTGGATCCCAGTCACCAAGCAAGCCTATTG
  GCAGATTGCCCTGGATGGAATCCAGGTGGGAGACACTGTGATGTTCTGCTCCGAAGGCTGCCAGGCCATA
  GTGGACACAGGGACCTCTCTCATCACTGGCCCCCCCGACAAGATCAAACAGCTTCAAGAGGCCATTGGGG
  CCACACCCATTGATGGAGAATATGCAGTGGATTGTGCCACTCTCGACACGATGCCAAACGTTACCTTCCT
  CATCAACGAGGTTTCATATACCCTCAACCCAACTGACTACATCCTGCCGGACTTGGTGGAAGGAATGCAG
  TTCTGTGGCAGTGGCTTTCAAGGACTTGACATTCCACCTCCAGCTGGGCCCCTCTGGATCCTGGGGGATG
  TCTTCATCCGACAGTTCTACTCAGTCTTTGACCGTGGAAATAACCAAGTGGGATTGGCCCCCGCAGTTCC
  C
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG206223 representing NM_007799
  Red=Cloning site Green=Tags(s)
  
  MKPLLVLLLLLLLDLAQAQGALHRVPLRRHQSLRKKLRAQGQLSEFWRSHNLDMTRLSESCNVYSSVNEP
  LINYLDMEYFGTISIGTPPQNFTVIFDTGSSNLWVPSVYCTSPACKAHPVFHPSQSDTYTEVGNHFSIQY
  GTGSLTGIIGADQVSVEGLTVDGQQFGESVKEPGQTFVNAEFDGILGLGYPSLAAGGVTPVFDNMMAQNL
  VALPMFSVYLSSDPQGGSGSELTFGGYDPSHFSGSLNWIPVTKQAYWQIALDGIQVGDTVMFCSEGCQAI
  VDTGTSLITGPPDKIKQLQEAIGATPIDGEYAVDCATLDTMPNVTFLINEVSYTLNPTDYILPDLVEGMQ
  FCGSGFQGLDIPPPAGPLWILGDVFIRQFYSVFDRGNNQVGLAPAVP
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007799
• ORF Size: 1191 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007799.3, NP_031825.2
• RefSeq Size: 2120
• RefSeq ORF: 1194
• Locus ID: 13034
• MW: 42.9 kDa
• Gene Summary: This gene encodes a member of the peptidase A1 family of aspartate proteases and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration. Homozygous knockout mice for this gene exhibit lysosomal storage disorder, impaired autophagy, mitochondrial abnormalities, dermatitis, and reduced weight gain in an obesity model. [provided by RefSeq, Aug 2015]