Ctsc (NM_009982) Mouse Tagged ORF Clone

CAT#: MG207379

Ctsc (GFP-tagged) - Mouse cathepsin C (Ctsc)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Ctsc
• Synonyms: AI047818; CatC; DPP1; DPPI
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG207379 representing NM_009982
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGTCCCTGGACCCACTCCTTGCGCGCCGTCCTGCTGCTGGTGCTTTTGGGAGTCTGCACCGTGCGCT
  CCGACACTCCTGCCAACTGCACCTACCCTGATCTGCTGGGCACCTGGGTGTTCCAGGTGGGCCCTAGAAG
  TTCCCGAAGCGACATTAACTGCTCGGTGATGGAAGCAACAGAAGAAAAGGTAGTGGTACACCTTAAGAAG
  TTGGATACTGCCTACGACGAGCTGGGCAATTCCGGGCATTTTACCCTCATTTACAACCAAGGCTTCGAGA
  TTGTGTTGAATGACTACAAATGGTTTGCGTTTTTCAAGTATGAAGTCAGAGGCCACACAGCTATCAGTTA
  CTGCCATGAGACCATGACTGGGTGGGTCCATGATGTGCTGGGCCGGAACTGGGCTTGCTTTGTTGGCAAG
  AAGGTGGAAAGTCACATTGAGAAGGTTAATATGAATGCAGCACATCTTGGAGGTCTCCAGGAAAGATATT
  CTGAAAGACTCTACACTCACAACCACAACTTTGTGAAGGCCATCAATACCGTTCAGAAGTCTTGGACTGC
  AACTGCATATAAGGAATATGAGAAAATGAGCCTGCGAGATCTGATAAGGAGAAGTGGCCACAGCCAAAGG
  ATCCCAAGGCCCAAACCTGCCCCGATGACTGATGAAATACAGCAACAAATTTTAAATTTGCCAGAATCTT
  GGGACTGGAGAAACGTCCAAGGCGTCAATTATGTTAGCCCTGTTCGAAACCAAGAATCTTGTGGAAGCTG
  CTACTCATTTGCCTCTATGGGTATGCTAGAAGCAAGAATTCGTATATTAACCAACAATTCTCAGACACCA
  ATCCTGAGTCCTCAGGAGGTTGTATCTTGCAGCCCCTATGCCCAAGGTTGTGATGGTGGATTCCCATACC
  TCATTGCAGGGAAGTATGCCCAAGATTTTGGGGTGGTGGAAGAAAGCTGCTTTCCCTACACAGCCAAAGA
  TTCTCCATGCAAACCAAGGGAGAATTGCCTCCGTTACTATTCTTCTGACTACTACTATGTGGGTGGTTTC
  TATGGTGGCTGCAATGAAGCCCTGATGAAGCTTGAGCTGGTCAAACATGGACCCATGGCAGTTGCCTTTG
  AAGTCCACGATGACTTCCTACACTACCACAGTGGAATCTATCACCACACTGGGCTGAGTGACCCTTTCAA
  CCCCTTCGAGCTGACAAATCATGCTGTTTTGCTTGTGGGCTATGGAAGAGATCCAGTTACTGGGATAGAA
  TACTGGATTATAAAGAACAGCTGGGGCTCTAACTGGGGGGAGAGTGGCTACTTCCGTATCCGCAGAGGAA
  CTGATGAATGTGCAATTGAGAGTATAGCCGTGGCGGCCATACCGATTCCTAAATTA
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG207379 representing NM_009982
  Red=Cloning site Green=Tags(s)
  
  MGPWTHSLRAVLLLVLLGVCTVRSDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKK
  LDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHETMTGWVHDVLGRNWACFVGK
  KVESHIEKVNMNAAHLGGLQERYSERLYTHNHNFVKAINTVQKSWTATAYKEYEKMSLRDLIRRSGHSQR
  IPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTP
  ILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEESCFPYTAKDSPCKPRENCLRYYSSDYYYVGGF
  YGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVTGIE
  YWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPIPKL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009982
• ORF Size: 1386 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009982.2, NP_034112.2
• RefSeq Size: 2444
• RefSeq ORF: 1389
• Locus ID: 13032
• Gene Summary: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the dipeptidyl peptidase 1 light, heavy, and exclusion domain chains, which together comprise one subunit of the homotetrameric enzyme. This enzyme has amino dipeptidase activity and may play a role in the activation of granzymes during inflammation. Homozygous knockout mice for this gene exhibit impaired granzyme activation and enhanced survival in a sepsis model. [provided by RefSeq, Aug 2015]