Loxl1 (NM_010729) Mouse Tagged ORF Clone

CAT#: MG209361

Loxl1 (GFP-tagged) - Mouse lysyl oxidase-like 1 (Loxl1)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Loxl1
• Synonyms: Loxl
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG209361 representing NM_010729
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTCTGGCCGGAGCCGGCAGCCAGCTGAGGACCCTGGTGTGGAGTGCCTGCCTGTGCGTCCTGGTGC
  ACGGGCAGCAAGCGCAGCCAGGACAGGGCTCGGACCCAGGACGCTGGCGGCAGCTGATCCAGTGGGAGAA
  CAACGGGCAGGTGTACAGCTTGCTCAACTCGGGCTCTGAGTACGTGCCCGCGGGGCCCCAACGAGGGGAG
  ACTAGCTCCAGGGTTCTACTGGCAGGCGCGCCCCAAACGTCGCAGCGGCGCAGTCAGGGGGGACCCCGGC
  GTCGGCAGGCGCCGTCCCTGCCCCTGCCCGGACGCGTGGGTTCGGACACTGTGCGCGGCCAAACGCGGCA
  CCCGTTCGGCTTCGGCCAGGTGCCCGACAACTGGAGAGAGGTGGCCGTCGGGGACAGTACCGGCATGGCT
  CGGGCCCGCACCTCCGTCTCCCAGCAACGGCACGGGGGCTCCGCCTCCTCCTCGGTTTCGGCCTCGGCCT
  TCGCCACCACCTATCGCCAGCCATCCTCCTACCCGCAGCAGTTCCCCTATCCGCAGGCGCCCTTCGTAAA
  CCAGTATGAGAACTACGATCCCGCGTCACGGACCTACGAACAGGGCTACGTGTACTACCGTGGTGCGGGC
  GGCGGCATGGGCGCGGGGGCAGCGGCTGTAGCCTCGGCTGGGGTCATCTATCCCTTCCAGCCCCGGGCGC
  GTTACGAGGACTACGGAGGTGGAGGAGGCGAGGAGCAGCCCGAGTACCCGGCCCAGGGCTTTTACCCAGC
  CCCAGAGAGGCCCTATGTGCCCCAGCCCCAACCCCAGCCCCAGCCCCAGCCGCAGCCTCAGCCCCAACCT
  TCCGACGGCCTTGACCGTCGTTACTCGCACAGCCTGTACAATGAAGGCACCCCGGGATTCGAGCAGGCCT
  ACCCTGATCCCAGCACCGACGTGTCGCAGGCCCCCGCGGGGGCCGGTGGCACCTACGGTGGCGCTGGCGA
  TCCTCGCCTCGGCTGGTACCCGCCCTATGCAGCCAATGTGCCACCGGAGGCCTACGTCCCTCCGCGTGCG
  GTGGAGCCACAGCCCCCATTCCGCGTGCTGGAGCCACCTTACTTGCCCGTGCGAAGCTCTGATGCGCCCT
  CCCAGGGTGGGGAGCGGAACGGCGCCCAGCAGGGCCGTCTCAGCGTGGGTAGTGTGTACCGACCCAACCA
  GAATGGTCGCGGCCTCCCTGACTTAGTCCCGGACCCTAACTACGTGCAGGCATCCACATACGTGCAGAGA
  GCCCATCTGTACTCCTTGCGATGCGCAGCAGAGGAGAAGTGCCTGGCCAGCACAGCCTATGCCCCTGAGG
  CTACCGACTATGACCTCCGAGTGCTATTGCGCTTCCCCCAGCGAGTGAAAAACCAAGGCACAGCGGACTT
  TCTCCCCAACCGGCCACGCCACACCTGGGAGTGGCATAGCTGTCACCAACATTACCACAGCATGGACGAG
  TTCAGCCACTACGACCTGCTTGATGCATCCACGGGCAAGAAGGTAGCCGAGGGACACAAGGCCAGCTTCT
  GCCTGGAGGACAGCACCTGTGACTTCGGCAACCTCAAGCGCTATGCCTGCACCTCTCACACGCAGGGCCT
  GAGTCCAGGCTGCTATGACACATACAATGCGGACATTGACTGCCAGTGGATCGACATAACTGATGTGCAG
  CCTGGGAACTACATCCTCAAGGTGCACGTGAACCCCAAGTACATTGTTCTGGAGTCTGACTTCACCAACA
  ACGTGGTGAGATGCAACATCCACTACACAGGTCGCTACGTTTCTACAACAAACTGCAAAATCGTCCAGTC
  C
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG209361 representing NM_010729
  Red=Cloning site Green=Tags(s)
  
  MALAGAGSQLRTLVWSACLCVLVHGQQAQPGQGSDPGRWRQLIQWENNGQVYSLLNSGSEYVPAGPQRGE
  TSSRVLLAGAPQTSQRRSQGGPRRRQAPSLPLPGRVGSDTVRGQTRHPFGFGQVPDNWREVAVGDSTGMA
  RARTSVSQQRHGGSASSSVSASAFATTYRQPSSYPQQFPYPQAPFVNQYENYDPASRTYEQGYVYYRGAG
  GGMGAGAAAVASAGVIYPFQPRARYEDYGGGGGEEQPEYPAQGFYPAPERPYVPQPQPQPQPQPQPQPQP
  SDGLDRRYSHSLYNEGTPGFEQAYPDPSTDVSQAPAGAGGTYGGAGDPRLGWYPPYAANVPPEAYVPPRA
  VEPQPPFRVLEPPYLPVRSSDAPSQGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQR
  AHLYSLRCAAEEKCLASTAYAPEATDYDLRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDE
  FSHYDLLDASTGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQ
  PGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSTTNCKIVQS
  
  SGPTRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene Plasmid Map
• ACCN: NM_010729
• ORF Size: 1821 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010729.2, NP_034859.2
• RefSeq Size: 2460
• RefSeq ORF: 1824
• Locus ID: 16949
• Gene Summary: This gene encodes a member of the lysyl oxidase family of copper-dependent enzymes that catalyze the formation of lysine-derived crosslinks in proteins such as collagen and elastin. The encoded preproprotein undergoes proteolytic processing to generate the mature, functional enzyme. Mice lacking the encoded protein fail to deposit normal elastic fibers in the uterine tract post partum and develop pelvic organ prolapse, enlarged airspaces of the lung, loose skin and vascular abnormalities with concomitant tropoelastin accumulation. [provided by RefSeq, Sep 2016]