Scnn1g (NM_011326) Mouse Tagged ORF Clone

CAT#: MG209793

Scnn1g (GFP-tagged) - Mouse sodium channel, nonvoltage-gated 1 gamma (Scnn1g)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Scnn1g
• Synonyms: SCNEG
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG209793 representing NM_011326
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCCTGGAGAGAAGATCAAAGCCAAAATCAAAAAGAATCTGCCAGTTCGAGGCCCCCAGGCACCGA
  CCATTAAGGACCTGATGCATTGGTACTGCCTGAACACCAACACCCACGGCTGCCGGCGCATCGTGGTGTC
  CCGAGGCCGCCTTCGGCGCCTGTTGTGGATTGCGTTCACGCTGACAGCAGTGGCCCTCATTATCTGGCAG
  TGCGCCCTCCTCGTCTTCTCTTTCTACACCGTCTCTGTCTCCATCAAAGTCCACTTCCAGAAACTGGATT
  TCCCCGCTGTCACTATCTGCAATATCAACCCCTACAAGTACAGTGCTGTGAGTGACCTCCTGACTGACTT
  GGACAGTGAGACAAAACAGGCCTTGCTGTCCTTGTATGGGGTCAAAGATGTTCTAGACAGTACACCTCGG
  AAACGCCGGGAAGCAGGATCCATGCGGTCCACGTGGGAAGGCACACCACCCAGATTTCTCAACCTGATCC
  CATTGTTGGTCTTCAATGAGAACGAGAAGGGAAAGGCCAGGGACTTCTTCACTGGTCGGAAGCGGAAAAT
  CAGTGGGAAAATCATACACAAGGCTTCTAATGTCATGCACGTTCATGAGTCGAAGAAACTGGTGGGATTT
  CAGTTGTGCTCAAATGACACCTCTGACTGTGCCACCTACACCTTCAGCTCAGGAATCAATGCCATCCAGG
  AGTGGTACAAACTTCACTACATGAATATCATGGCACAGGTGCCTCTAGAGAAGAAAATCAACATGAGCTA
  TTCTGCCGAAGAACTGCTGGTGACCTGCTTCTTCGATGGGATGTCCTGTGATGCCAGGAACTTCACTCTT
  TTCCACCATCCAATGTATGGGAACTGCTACACGTTCAACAACAGAGAAAACGCCACCATCCTCAGCACCT
  CCATGGGAGGCAGTGAGTATGGTCTGCAAGTCATCTTATACATAAACGAAGATGAGTACAACCCCTTCCT
  GGTGTCATCCACTGGAGCCAAGGTGCTTGTCCATCAGCAGAATGAATACCCTTTCATCGAAGACGTGGGG
  ACCGAGATCGAGACAGCAATGTCCACTTCCATAGGAATGCACCTGACAGAATCCTTCAAGCTGAGCGAAC
  CTTACAGCCAGTGCACAGAGGACGGCAGCGATGTGCCCGTCACAAACATCTACAATGCTGCCTATTCCCT
  CCAGATCTGCCTTTACTCATGCTTCCAAACGAAGATGGTGGAAAAATGTGGCTGTGCCCAGTACAGTCAG
  CCTCTACCTCCAGCAGCCAATTACTGCAACTACCAGCAACACCCCAACTGGATGTATTGCTACTACCAGC
  TGTACCAGGCCTTTGTCCGGGAAGAACTGGGCTGCCAATCAGTGTGCAAGCAATCCTGCAGCTTTAAGGA
  ATGGACACTGACCACCAGCTTGGCACAGTGGCCATCTGAGGCTTCTGAGAAATGGTTGCTGAATGTTCTC
  ACCTGGGACCAAAGCCAGCAAATAAACAAAAAGCTCAACAAGACTGACCTGGCCAAGCTCTTGATATTCT
  ACAAAGACCTGAACCAAAGATCCATCATGGAGAGCCCAGCCAACAGTATTGAGATGCTCCTGTCTAACTT
  TGGTGGACAGCTCGGCCTGTGGATGAGCTGCTCGGTCGTCTGTGTCATCGAAATCATCGAAGTCTTCTTC
  ATTGATTTCTTCTCTATTATTGCCCGCCGCCAGTGGCAGAAAGCCAAGGATTGGTGGGCCCGTAGGCGGA
  CACCACCCTCCACTGAGACTCCCTCCAGCCAGCAGGGTCAGGATAATCCAGCCCTGGATACGGACGATGA
  TCTGCCCACTTTTACCTCTGCTATGCGCCTGCCTCCAGCCCCGGAGGCTCCGGTGCCTGGCACACCACCC
  CCCAGATACAATACCTTGCGCTTGGACAGTGCCTTTTCCTCCCAGCTCACAGACACTCAGTTGACCAATG
  AGTTC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG209793 representing NM_011326
  Red=Cloning site Green=Tags(s)
  
  MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCLNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQ
  CALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPR
  KRREAGSMRSTWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGF
  QLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTL
  FHHPMYGNCYTFNNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVG
  TEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQ
  PLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVL
  TWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFF
  IDFFSIIARRQWQKAKDWWARRRTPPSTETPSSQQGQDNPALDTDDDLPTFTSAMRLPPAPEAPVPGTPP
  PRYNTLRLDSAFSSQLTDTQLTNEF
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_011326
• ORF Size: 1965 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011326.2, NP_035456.1
• RefSeq Size: 2965
• RefSeq ORF: 1968
• Locus ID: 20278
• Gene Summary: This gene encodes the gamma subunit of the epithelial sodium channel, a member of the amiloride-sensitive sodium channel family of proteins. This channel regulates sodium homeostasis and blood pressure, by controlling sodium transport in the kidney, colon and lung. Proteolytic processing of the encoded protein results in the release of an inhibitory peptide and channel activation. Homozygous knockout mice for this gene exhibit perinatal lethality, likely due to excess serum potassium. [provided by RefSeq, Oct 2015]