Bmp1 (NM_009755) Mouse Tagged ORF Clone

CAT#: MG211396

Bmp1 (GFP-tagged) - Mouse bone morphogenetic protein 1 (Bmp1)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Bmp1
• Synonyms: Pcp; Tld
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG211396 representing NM_009755
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCGGCGTGGCCCGCCCGCCGCTGCCGCTGCTGTCGCTGCCGCTGCTACTGCTGCTGCTGCTGCTCC
  CGCGCGCCGGCCGGCCGCTGGACTTGGCCGACTACACCTACGACCTGGGCGAGGAGGACGCCCCGGAGCT
  CCTCAACTACAAAGACCCTTGCAAGGCGGCTGCCTTCCTTGGGGACATTGCCCTGGATGAGGAGGACTTG
  AGGGCCTTCCAGGTGCAGCAGGCTGCAGTTCTCAGACAGCAAACAGCCCGAAGGCCATCCATCAAAGCTG
  CAGGAAACTCTTCTGCCCTGGGTGGTCAGGGCACTAGTGGACAGCCGCAGAGGGAAAGCAGGGGCAGATG
  GAGAGGCAGGCCTCGGAGCAGGCGGGCAGCGACGTCCAGACCGGAGCGGGTGTGGCCCGATGGGGTCATC
  CCGTTTGTGATTGGAGGGAATTTCACCGGCAGCCAGAGGGCAGTCTTCCGGCAGGCCATGAGACACTGGG
  AGAAGCATACCTGTGTCACCTTCTTGGAGCGCACAGATGAGGACAGCTATATTGTATTCACCTACCGACC
  CTGCGGGTGCTGCTCCTACGTGGGTCGCCGAGGTGGGGGCCCCCAGGCCATCTCCATCGGCAAGAACTGT
  GACAAGTTTGGCATCGTGGTCCATGAGCTGGGCCATGTCATTGGCTTCTGGCACGAGCACACGCGGCCCG
  ACCGGGACCGCCATGTCTCTATTGTACGCGAGAACATACAGCCAGGGCAGGAGTATAACTTCTTGAAGAT
  GGAGGTTCAAGAAGTGGAGTCCTTGGGAGAGACCTATGACTTTGACAGTATCATGCACTATGCCCGGAAC
  ACATTCTCCAGGGGCATCTTCTTGGACACCATTGTTCCCAAGTATGAGGTGAATGGGGTGAAGCCTTCCA
  TTGGCCAAAGGACCCGACTCAGCAAGGGGGACATCGCTCAGGCCCGGAAGCTCTACAAATGCCCAGCCTG
  TGGCGAGACCCTCCAAGACAGCACTGGCAACTTCTCCTCCCCTGAGTATCCCAATGGCTACTCTGCCCAC
  ATGCACTGTGTATGGCGCATCTCTGTCACACCTGGGGAGAAGATTATTCTAAACTTCACATCCATGGACC
  TGTACCGTAGCCGCCTGTGCTGGTATGACTATGTGGAGGTGCGGGATGGCTTCTGGAGAAAGGCGCCCCT
  CCGAGGCCGGTTCTGTGGGGGCAAACTCCCCGAGCCCATCGTCTCCACCGACAGCCGCCTCTGGGTGGAA
  TTCCGAAGCAGCAGCAACTGGGTTGGAAAGGGCTTCTTTGCTGTCTATGAAGCCATTTGCGGTGGCGATG
  TGAAAAAGGATAATGGCCATATCCAGTCTCCCAATTACCCAGACGATTATCGGCCCAGCAAAGTCTGCAT
  CTGGCGGATCCAGGTGTCTGAGGGTTTCCACGTGGGCCTCACGTTCCAGTCCTTTGAGATTGAGCGTCAC
  GACAGTTGTGCCTACGACTACCTGGAAGTCCGTGATGGGCACAGCGAGAGCAGCAACCTCATTGGGCGCT
  ACTGTGGCTATGAGAAGCCTGATGACATCAAAAGCACATCCAGTCGGCTCTGGCTCAAGTTCGTCTCTGA
  CGGGTCCATTAACAAAGCTGGCTTCGCAGTCAACTTTTTCAAAGAGGTGGATGAGTGTTCAAGGCCCAAC
  CGCGGGGGCTGTGAGCAGCGGTGCCTGAACACCCTGGGCAGCTACAAGTGCAGCTGTGACCCTGGCTATG
  AGCTGGCCCCAGACAAGCGTCGGTGTGAGGCTGCCTGTGGTGGATTCCTCACCAAGCTCAATGGCTCCAT
  CACCAGCCCCGGTTGGCCCAAAGAGTACCCTCCCAACAAAAACTGCATCTGGCAGTTGGTGGCCCCCACC
  CAGTACCGTATCTCCCTGCAATTTGACTTCTTCGAGACTGAGGGCAATGATGTGTGCAAGTACGACTTTG
  TGGAGGTGCGCAGCGGACTCACGGCGGACTCTAAGCTGCATGGCAAGTTCTGCGGCTCCGAGAAGCCAGA
  GGTCATCACTTCCCAGTACAACAATATGCGTGTGGAGTTCAAGTCTGACAATACTGTGTCCAAAAAGGGC
  TTCAAGGCCCACTTCTTCTCAGATAAGGATGAATGTTCCAAGGACAATGGTGGATGCCAGCAAGACTGTG
  TGAACACGTTCGGCAGCTACGAGTGTCAGTGCCGCAGTGGCTTCGTCCTTCACGACAACAAACATGACTG
  TAAAGAAGCTGGCTGTGAACACAAGGTGACATCCACCAGTGGCACCATCACCAGCCCCAACTGGCCTGAC
  AAGTACCCCAGCAAGAAGGAGTGTACGTGGGCTATCTCCAGCACCCCTGGGCACCGGGTAAAGCTGACTT
  TCGTGGAGATGGATATTGAGTCTCAGCCCGAGTGTGCTTATGACCACCTGGAGGTGTTCGATGGACGTGA
  TGCCAAGGCACCAGTCCTTGGACGATTCTGTGGCAGTAAGAAGCCTGAGCCAGTCCTGGCTACAGGCAAC
  CGCATGTTCTTGCGCTTCTACTCAGACAACTCGGTACAGAGGAAAGGTTTCCAGGCATCCCACTCCACAG
  AGTGTGGGGGCCAAGTGCGGGCAGATGTGAAGACCAAAGACCTTTATTCCCATGCCCAGTTCGGCGATAA
  CAACTACCCTGGAGGGGTGGACTGCGAGTGGGTCATCGTGGCCGAGGAAGGCTATGGCGTGGAGCTGGTG
  TTCCAGACCTTCGAGGTGGAGGAGGAGACTGACTGTGGCTATGACTACATAGAGCTCTTTGATGGCTACG
  ACAGCACAGCTCCCAGACTGGGGCGCTACTGTGGTTCTGGGCCTCCCGAGGAAGTGTACTCGGCTGGAGA
  TTCTGTCCTGGTGAAGTTCCACTCTGACGACACCATCTCCAAGAAAGGCTTCCACCTGCGGTACACAAGC
  ACCAAGTTCCAGGACACACTCCACAGCAGGAAG
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG211396 representing NM_009755
  Red=Cloning site Green=Tags(s)
  
  MPGVARPPLPLLSLPLLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDL
  RAFQVQQAAVLRQQTARRPSIKAAGNSSALGGQGTSGQPQRESRGRWRGRPRSRRAATSRPERVWPDGVI
  PFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNC
  DKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARN
  TFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAH
  MHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVE
  FRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERH
  DSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN
  RGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPT
  QYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKG
  FKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPD
  KYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGN
  RMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELV
  FQTFEVEEETDCGYDYIELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTS
  TKFQDTLHSRK
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009755
• ORF Size: 2973 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009755.3, NP_033885.2
• RefSeq Size: 3769
• RefSeq ORF: 2976
• Locus ID: 12153
• Gene Summary: This gene encodes a metalloproteinase that plays an essential role in the formation of the extracellular matrix and is also able to induce ectopic bone formation. Unlike other bone morphogenetic proteins, the protein encoded by this gene is not closely related to transforming growth factor-beta. This protein plays in role several developmental processes. In humans, mutations in this gene are associated with osteogenesis imperfecta and with increased bone mineral density and multiple recurrent fractures. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]