Mb21d1 (NM_173386) Mouse Tagged ORF Clone

CAT#: MG213022

MB21D1 (GFP-tagged) - Mouse Mab-21 domain containing 1 (Mb21d1), (10ug)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Mb21d1
• Synonyms: E330016A19Rik; Mb21d1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG213022 representing NM_173386
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAAGATCCGCGTAGAAGGACGACGGCGCCACGCGCTAAGAAGCCGTCCGCGAAGCGCGCCCCGACGC
  AGCCCAGCAGGACCAGGGCCCACGCGGAAAGCTGCGGCCCGCAAAGGGGGGCTCGATCGCGGCGGGCGGA
  GCGTGACGGGGACACCACGGAGAAGCCACGTGCCCCAGGGCCCCGAGTGCATCCAGCAAGGGCCACTGAG
  CTCACCAAAGATGCACAGCCCTCGGCCATGGACGCGGCAGGAGCCACCGCGCGGCCTGCCGTCCGGGTGC
  CCCAGCAGCAGGCCATCCTGGATCCGGAGCTGCCCGCCGTACGGGAGCCCCAGCCGCCCGCGGATCCCGA
  GGCGCGGAAAGTCGTAAGGGGACCTAGCCACAGAAGGGGCGCGCGCTCCACCGGGCAGCCCAGAGCGCCG
  CGAGGGTCCAGGAAGGAACCGGACAAGCTAAAGAAGGTGCTGGACAAATTGAGATTGAAACGCAAAGATA
  TCTCGGAGGCGGCCGAGACGGTGAATAAAGTTGTGGAACGCCTGCTGCGCAGAATGCAGAAACGGGAGTC
  GGAGTTCAAAGGTGTGGAGCAGCTGAACACTGGCAGCTACTATGAACATGTGAAGATTTCTGCTCCTAAT
  GAATTTGATGTTATGTTTAAACTGGAAGTCCCCAGGATTGAGCTACAAGAATATTATGAAACAGGTGCTT
  TTTATCTTGTGAAATTCAAAAGAATTCCACGAGGAAATCCGCTGAGTCATTTCTTAGAAGGGGAAGTATT
  ATCAGCTACCAAGATGCTGTCAAAGTTTAGGAAAATCATTAAAGAAGAAGTTAAAGAAATCAAAGATATA
  GATGTCAGTGTGGAGAAGGAAAAACCAGGAAGCCCTGCTGTAACACTTCTTATCAGGAACCCTGAAGAAA
  TCTCTGTGGATATAATTCTGGCTTTGGAGTCAAAAGGCAGCTGGCCTATTAGTACCAAAGAAGGACTACC
  TATTCAAGGCTGGCTGGGCACAAAAGTGAGGACCAATCTAAGACGAGAGCCGTTTTATCTCGTACCCAAG
  AATGCAAAGGATGGAAATAGTTTTCAAGGAGAGACCTGGCGCCTCTCTTTCTCTCACACTGAAAAGTACA
  TTTTGAATAATCACGGGATAGAGAAAACATGCTGTGAATCTTCCGGAGCAAAATGCTGCAGAAAAGAATG
  TTTAAAATTAATGAAATACCTTTTGGAACAGTTGAAAAAAGAGTTTCAAGAGCTGGATGCATTCTGTTCC
  TACCATGTGAAAACTGCCATCTTTCACATGTGGACCCAGGACCCGCAGGACAGTCAGTGGGACCCCAGGA
  ACCTCAGCTCCTGCTTCGATAAGTTGTTAGCATTCTTTCTTGAGTGCCTCAGGACAGAGAAACTGGATCA
  TTATTTTATTCCAAAGTTCAATCTATTCTCTCAAGAACTAATTGACCGAAAAAGTAAAGAATTTCTATCG
  AAGAAAATTGAATATGAAAGAAATAATGGGTTTCCAATTTTTGACAAGCTT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG213022 representing NM_173386
  Red=Cloning site Green=Tags(s)
  
  MEDPRRRTTAPRAKKPSAKRAPTQPSRTRAHAESCGPQRGARSRRAERDGDTTEKPRAPGPRVHPARATE
  LTKDAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQPPADPEARKVVRGPSHRRGARSTGQPRAP
  RGSRKEPDKLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTGSYYEHVKISAPN
  EFDVMFKLEVPRIELQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDI
  DVSVEKEKPGSPAVTLLIRNPEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPK
  NAKDGNSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCS
  YHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLS
  KKIEYERNNGFPIFDKL
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_173386
• ORF Size: 1521 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_173386.4, NP_775562.2
• RefSeq Size: 4000
• RefSeq ORF: 1524
• Locus ID: 214763
• Gene Summary: The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]