Bmp5 (NM_007555) Mouse Tagged ORF Clone

CAT#: MG222932

Bmp5 (GFP-tagged) - Mouse bone morphogenetic protein 5 (Bmp5), (10ug)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Bmp5
• Synonyms: AU023399; se
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG222932 representing NM_007555
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCATTGGACTGTATTTTTACTTAGGGGTATTGTGGGCTTCCTCTGGAGCGGCTGGGTTCAAGTGGGTT
  ATGCAAAAGGAGGCTTGGGAGACAATCACGTTCACTCCAGTTTTATTTATAGAAGGCTACGGAACCATGA
  GAGACGGGAAATACAGAGGGAAATTCTGTCTATTTTGGGTTTGCCTCACAGACCCAGGCCCTTTTCACCA
  GGGAAACAAGCATCTTCTGCCCCCCTCTTTATGCTGGATCTCTACAATGCCATGGCTAGCGAAGACAACC
  CTGAGGAGTATTTGGTGAGGGTGTCCCTGGCTGGAGAGGCCAAAGAGACAAGAAAGGGATACCCAGCCTC
  TCCCAATGGGTATGCGCATCGTCTGCACTTACCACCAAGGACTCCTCTGACTACCCAGAGCCCACCTCTT
  GCCAGCCTACATGATACCAACTTTCTGAATGATGCTGACATGGTCATGAGCTTTGTCAACTTAGTTGAAA
  GAGACAAGGACTTTTCTCATCAGAGGAGGCATTACAAAGAGTTTCGGTTTGATCTGACCCAGATTCCACA
  TGGAGAAGCAGTGACAGCAGCAGAATTCCGGATTTATAAGGACAAGGGAAACCATCGATTTGAAAATGAA
  ACAATTAAGATCAGCATATATCAGATCATCAAGGAATACACAAACAGGGATGCAGATCTTTTTCTGCTAG
  ATACGAGGAAGACACAAGCTTTAGATGTGGGCTGGCTTGTCTTTGATATCACTGTGACCAGCAACCACTG
  GGTGATTAATCCACAGAACAATTTGGGCTTACAGCTCTGTGCAGAGACGGGGGATGGCCGCAGCATCAAT
  GTAAAATCTGCTGGTCTTGTGGGAAGACATGGGCCTCAGTCAAAACAGCCATTCATGGTGGCCTTCTTCA
  AGGCAAGCGAGGTACTTCTTCGATCCGTGAGAGCAGCCAGCAAACGGAAAAATCAAAACCGCAATAAATC
  CAACTCTCATCAGGACCCCTCCAGGATGCCCAGTGCTGGAGATTATAATACCAGTGAACAAAAACAAGCC
  TGCAAGAAGCACGAACTCTATGTGAGTTTCCGAGATCTGGGATGGCAGGACTGGATCATAGCACCAGAAG
  GGTATGCTGCATTTTATTGTGACGGGGAATGTTCTTTTCCACTTAATGCCCATATGAATGCCACCAACCA
  TGCCATAGTCCAGACCCTGGTACACCTGATGTTTCCAGACCATGTTCCCAAGCCTTGCTGTGCTCCAACC
  AAACTAAATGCCATCTCGGTCCTGTATTTTGATGACAGCTCCAATGTCATTTTGAAAAAGTACAGAAATA
  TGGTAGTACGTTCGTGTGGCTGCCAC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG222932 representing NM_007555
  Red=Cloning site Green=Tags(s)
  
  MHWTVFLLRGIVGFLWSGWVQVGYAKGGLGDNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSP
  GKQASSAPLFMLDLYNAMASEDNPEEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRTPLTTQSPPL
  ASLHDTNFLNDADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDKGNHRFENE
  TIKISIYQIIKEYTNRDADLFLLDTRKTQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGDGRSIN
  VKSAGLVGRHGPQSKQPFMVAFFKASEVLLRSVRAASKRKNQNRNKSNSHQDPSRMPSAGDYNTSEQKQA
  CKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPT
  KLNAISVLYFDDSSNVILKKYRNMVVRSCGCH
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007555
• ORF Size: 1362 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007555.3, NP_031581.2
• RefSeq Size: 2528
• RefSeq ORF: 1365
• Locus ID: 12160
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Mice with null mutations in this gene exhibit a short ear phenotype, which is characterized by reduced size of the external ear, altered size and shape of the sternum, and other skeletal and soft-tissue abnormalities. [provided by RefSeq, Jul 2016]