Gdf11 (NM_010272) Mouse Tagged ORF Clone

CAT#: MG223819

Gdf11 (GFP-tagged) - Mouse growth differentiation factor 11 (Gdf11), (10ug)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Gdf11
• Synonyms: BMP-11; Bmp11
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG223819 representing NM_010272
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGCTCGCGGCCCCGCTGCTGCTGGGCTTCCTGCTCCTCGCCCTGGAGCTGCGGCCCCGGGGGGAGG
  CGGCCGAGGGCCCCGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCCGGGGTCGGGGGGGAGCGCTCGAG
  CCGGCCGGCCCCGTCCGCTCCGCCGGAGCCGGACGGCTGCCCCGTGTGCGTGTGGCGGCAGCACAGCCGC
  GAGCTGCGCCTAGAGAGCATCAAGTCGCAGATCCTGAGCAAACTGCGGCTCAAGGAGGCGCCCAACATCA
  GCCGGGAGGTAGTGAAGCAGCTGCTGCCCAAGGCGCCGCCGCTGCAGCAGATCCTGGATCTGCACGACTT
  CCAAGGCGACGCGCTGCAGCCTGAGGACTTCTTGGAAGAGGACGAGTACCACGCTACCACCGAGACGGTC
  ATAAGCATGGCCCAGGAGACGGACCCTGCAGTGCAGACAGATGGCAGCCCTCTCTGCTGTCATTTCCACT
  TCAGCCCCAAGGTGATGTTCACCAAGGTACTGAAGGCCCAACTGTGGGTGTACCTTCGGCCTGTGCCCCG
  CCCAGCCACAGTCTACCTGCAGATCTTACGACTGAAACCCCTAACTGGGGAAGGGACCGCAGGGGGAGGG
  GGTGGAGGCCGGCGTCACATCCGTATCCGTTCACTAAAGATTGAGCTACACTCACGTTCCGGCCACTGGC
  AGAGCATCGACTTCAAGCAAGTGCTACACAGCTGGTTTCGCCAGCCACAGAGCAACTGGGGAATCGAGAT
  CAACGCCTTTGATCCCAGCGGCACAGACCTGGCTGTCACCTCCCTGGGGCCAGGAGCTGAGGGGCTGCAT
  CCTTTCATGGAGCTTCGAGTCCTAGAGAACACGAAAAGGTCCCGGCGGAACCTAGGCCTGGACTGCGATG
  AACACTCGAGTGAGTCCCGCTGCTGCCGATATCCTCTCACAGTGGACTTTGAGGCTTTTGGCTGGGACTG
  GATCATCGCACCTAAGCGCTACAAGGCCAACTACTGCTCCGGCCAGTGCGAATACATGTTCATGCAAAAG
  TATCCACACACCCACTTGGTGCAACAGGCCAACCCAAGAGGCTCTGCTGGGCCCTGCTGCACCCCTACCA
  AGATGTCCCCAATCAACATGCTCTACTTCAATGACAAGCAGCAGATTATCTACGGCAAGATCCCTGGCAT
  GGTGGTGGATCGATGTGGCTGCTCC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG223819 representing NM_010272
  Red=Cloning site Green=Tags(s)
  
  MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAGVGGERSSRPAPSAPPEPDGCPVCVWRQHSR
  ELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQGDALQPEDFLEEDEYHATTETV
  ISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQLWVYLRPVPRPATVYLQILRLKPLTGEGTAGGG
  GGGRRHIRIRSLKIELHSRSGHWQSIDFKQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLH
  PFMELRVLENTKRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQK
  YPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_010272
• ORF Size: 1215 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010272.1, NP_034402.1
• RefSeq Size: 1811
• RefSeq ORF: 1218
• Locus ID: 14561
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. Mice lacking a functional copy of this gene exhibit impaired anteroposterior patterning and other developmental defects. [provided by RefSeq, Aug 2016]