Crem (NM_001110853) Mouse Tagged ORF Clone

CAT#: MG224736

Crem (GFP-tagged) - Mouse cAMP responsive element modulator (Crem) transcript variant 9, (10ug)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: TurboGFP
• Symbol: Crem
• Synonyms: ICER; ICERI
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MG224736 representing NM_001110853
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTTTCTGTAGCTGGATCAGGCACTGGAAGAGGCTCCCCAGCTGTGACTCTAGTACAGTTACCTTCAG
  GCCAAACTGTACAGGTCCAGGGAGTTATTCAGACACCACATCCATCGGTTATTCAATCACCACAAATACA
  AACTGTTCAGGTAGCAACAATTGCAGAGACAGATGATTCTGCAGACTCAGAAGTAATTGATTCGCATAAA
  CGTAGAGAAATTCTTTCACGAAGACCCTCATATAGAAAAATACTGAATGAACTTTCCTCTGATGTGCCTG
  GTATTCCCAAGATTGAAGAAGAAAAATCAGAGGAAGAAGGGACACCACCTAACATTGCTACCATGGCAGT
  ACCAACTAGCATATATCAGACTAGCACGGGGCAATACATTGCTATAGCTCAAGGTGGAACAATCCAGATT
  TCTAACCCAGGATCTGATGGTGTTCAGGGACTCCAGGCATTAACAATGACAAATTCAGGAGCTCCTCCGC
  CAGGTGCTACAATTGTACAGTATGCAGCACAATCAGCCGATGGTACACAGCAGTTCTTTGTCCCAGGCAG
  CCAGGTTGTTGTTCAAGATGAGGAGACTGACCTTGCCCCAAGTCACATGGCTGCTGCCACAGGTGACATG
  CCAACTTACCAGATCCGAGCTCCTACTACTGCTTTGCCACAAGGTGTGGTGATGGCTGCCTCACCAGGAA
  GCCTGCACAGTCCCCAGCAACTAGCAGAAGAAGCAACTCGCAAGCGGGAGCTGAGGCTGATGAAAAACAG
  GGAAGCTGCTAAAGAATGTCGACGTCGAAAGAAAGAGTATGTGAAGTGTCTTGAGAGTCGAGTCGCAGTG
  CTGGAAGTTCAGAACAAGAAGCTTATAGAGGAGCTTGAAACTTTGAAAGACATTTGCTCTCCCAAAACAG
  AT
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >MG224736 representing NM_001110853
  Red=Cloning site Green=Tags(s)
  
  MVSVAGSGTGRGSPAVTLVQLPSGQTVQVQGVIQTPHPSVIQSPQIQTVQVATIAETDDSADSEVIDSHK
  RREILSRRPSYRKILNELSSDVPGIPKIEEEKSEEEGTPPNIATMAVPTSIYQTSTGQYIAIAQGGTIQI
  SNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFVPGSQVVVQDEETDLAPSHMAAATGDM
  PTYQIRAPTTALPQGVVMAASPGSLHSPQQLAEEATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAV
  LEVQNKKLIEELETLKDICSPKTD
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001110853
• ORF Size: 912 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001110853.2, NP_001104323.1
• RefSeq Size: 2192
• RefSeq ORF: 915
• Locus ID: 12916
• Gene Summary: This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as either activators or repressors of transcription. Activity of this gene is important in multiple developmental processes, including spermatogenesis. Mutation of this gene causes male infertility. Alternative splicing and promoter usage result in multiple transcript variants for this gene. [provided by RefSeq, Oct 2012]