C1qtnf5 (NM_001190319) Mouse Tagged ORF Clone

CAT#: MR203025

C1qtnf5 (Myc-DDK-tagged) - Mouse C1q and tumor necrosis factor related protein 5 (C1qtnf5), transcript variant 5

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: C1qtnf5
• Synonyms: Adie; Ctrp5; Mfrp
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR203025 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGGCCACTTCTTGCCCTTCTGCTTCTGGGTCTGGTGTCAGGCTCTCCTCCTCTGGACGACAACAAGA
  TCCCCAGCCTGTGTCCCGGGCAGCCCGGCCTTCCAGGCACACCAGGTCACCATGGCAGCCAAGGCCTGCC
  TGGCCGTGACGGCCGTGATGGCCGCGACGGTGCACCCGGAGCCCCGGGAGAGAAAGGCGAGGGCGGGAGA
  CCGGGACTACCTGGGCCACGTGGGGAGCCCGGGCCGCGTGGAGAGGCAGGGCCCATGGGGGCTATCGGGC
  CTGCGGGGGAGTGCTCGGTACCCCCACGATCAGCCTTCAGTGCCAAGCGATCCGAGAGCCGGGTACCTCC
  GCCAGCCGACACACCCCTACCTTTCGACCGTGTGCTGCTAAATGAGCAGGGCCATTTCGACCCCACTACT
  GGCAAGTTCACCTGCCAAGTGCCTGGCGTCTACTACTTTGCTGTGCACGCCACTGTCTACCGGGCCAGCT
  TGCAGTTTGATCTTGTCAAAAACGGGCAGTCCATCGCCTCTTTCTTCCAGTATTTTGGGGGGTGGCCCAA
  GCCAGCCTCGCTCTCAGGGGGTGCGATGGTAAGGCTAGAACCTGAGGACCAGGTGTGGGTGCAGGTGGGC
  GTGGGTGATTACATTGGCATCTATGCCAGCATCAAGACAGACAGTACCTTCTCTGGATTTCTCGTCTATT
  CTGACTGGCACAGCTCCCCAGTCTTCGCT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR203025 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MRPLLALLLLGLVSGSPPLDDNKIPSLCPGQPGLPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGR
  PGLPGPRGEPGPRGEAGPMGAIGPAGECSVPPRSAFSAKRSESRVPPPADTPLPFDRVLLNEQGHFDPTT
  GKFTCQVPGVYYFAVHATVYRASLQFDLVKNGQSIASFFQYFGGWPKPASLSGGAMVRLEPEDQVWVQVG
  VGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001190319
• ORF Size: 732 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001190319.1, NP_001177248.1
• RefSeq Size: 1350
• RefSeq ORF: 732
• Locus ID: 235312
• MW: 25.4 kDa
• Gene Summary: The protein encoded by this gene is a member of the C1q/tumor necrosis factor superfamily. This family member is a secretory protein that functions in eye development. Mutations in this gene are thought to underlie the pathophysiology of late-onset retinal degeneration (L-ORD) and early-onset long anterior zonules (LAZ). Bicistronic transcripts composed of the coding sequences for this gene (C1qtnf5) and the membrane-type frizzled-related protein gene (Mfrp) have been identified, and the resulting products can interact with each other. Co-transcription of C1qtnf5 and Mfrp has been observed in both human and mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]