M6pr (NM_010749) Mouse Tagged ORF Clone

CAT#: MR203749L4

Lenti ORF clone of M6pr (mGFP-tagged) - Mouse mannose-6-phosphate receptor, cation dependent (M6pr)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: M6pr
• Synonyms: CD-MPR; Mpr46
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR203749).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_010749
• ORF Size: 837 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010749.6, NP_034879.2
• RefSeq Size: 2258
• RefSeq ORF: 837
• Locus ID: 17113
• Gene Summary: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. [UniProtKB/Swiss-Prot Function]