Sfrp2 (NM_009144) Mouse Tagged ORF Clone

CAT#: MR204070

Sfrp2 (Myc-DDK-tagged) - Mouse secreted frizzled-related protein 2 (Sfrp2)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Sfrp2
• Synonyms: AI851596; Sdf5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR204070 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCGCGGGGCCCTGCCTCGCTGCTGCTGCTAGTCCTCGCCTCGCACTGCTGCCTGGGCTCGGCGCGTG
  GGCTCTTCCTCTTCGGCCAGCCCGACTTCTCCTACAAGCGCAGCAACTGCAAGCCCATCCCCGCCAACCT
  GCAGCTGTGCCACGGCATCGAGTACCAGAACATGCGGCTGCCCAACCTGCTGGGCCACGAGACCATGAAG
  GAGGTGCTGGAGCAGGCGGGCGCCTGGATTCCGCTGGTCATGAAGCAGTGCCACCCGGACACCAAGAAGT
  TCCTGTGCTCGCTCTTCGCCCCTGTCTGTCTCGACGACCTAGATGAGACCATCCAGCCGTGTCACTCGCT
  CTGCGTGCAGGTGAAGGACCGCTGCGCCCCGGTCATGTCCGCCTTCGGCTTCCCCTGGCCAGACATGCTG
  GAGTGCGACCGTTTCCCGCAGGACAACGACCTCTGCATCCCCCTCGCTAGTAGCGACCACCTCCTGCCGG
  CCACAGAGGAAGCTCCCAAGGTGTGTGAAGCCTGCAAAACCAAGAATGAGGACGACAACGACATCATGGA
  AACCCTTTGTAAAAATGACTTCGCACTGAAAATCAAAGTGAAGGAGATAACGTACATCAACAGAGACACC
  AAGATCATCCTGGAGACAAAGAGCAAGACCATTTACAAGCTGAACGGCGTGTCCGAAAGGGACCTGAAGA
  AATCCGTGCTGTGGCTCAAAGACAGCCTGCAGTGCACCTGTGAGGAGATGAACGACATCAACGCTCCGTA
  TCTGGTCATGGGACAGAAGCAGGGCGGCGAGCTGGTGATCACCTCCGTGAAACGGTGGCAGAAGGGCCAG
  AGAGAGTTCAAGCGCATCTCCCGCAGCATCCGCAAGCTGCAATGC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR204070 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MPRGPASLLLLVLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMK
  EVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDML
  ECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKTKNEDDNDIMETLCKNDFALKIKVKEITYINRDT
  KIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKRWQKGQ
  REFKRISRSIRKLQC
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009144
• ORF Size: 888 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009144.1, NM_009144.2, NP_033170.1
• RefSeq Size: 2001
• RefSeq ORF: 888
• Locus ID: 20319
• MW: 33.5 kDa
• Gene Summary: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. [UniProtKB/Swiss-Prot Function]