Prkar1a (NM_021880) Mouse Tagged ORF Clone

CAT#: MR205941L4

Lenti ORF clone of Prkar1a (mGFP-tagged) - Mouse protein kinase, cAMP dependent regulatory, type I, alpha (Prkar1a)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Prkar1a
• Synonyms: 1300018C22Rik; RIalpha; Tse-1; Tse1
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR205941).
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene
• ACCN: NM_021880
• ORF Size: 1143 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021880.1, NP_068680.1
• RefSeq Size: 3324
• RefSeq ORF: 1146
• Locus ID: 19084
• Gene Summary: The encoded protein is a regulatory subunit of the cAMP-dependent protein kinase (PKA) complex, which is responsible for transducing most of the cAMP signals in eukaryotic cells. The inactive PKA complex contains two regulatory and two catalytic subunits. Binding of cAMP dissociates the complex, allowing monomeric catalytic subunits to phosphorylate cytosolic proteins or induce gene expression in the nucleus. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2015]