Bmpr1b (NM_007560) Mouse Tagged ORF Clone

CAT#: MR208067

Bmpr1b (Myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1B (Bmpr1b)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Bmpr1b
• Synonyms: Acvrlk6; AI385617; ALK-6; Alk6; AV355320; BMPR-1B; BMPR-IB; CFK-43a; SKR6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR208067 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTCTTACGAAGCTCTGGAAAATTAAATGTGGGCACCAAGAAGGAGGATGGAGAGAGTACAGCCCCCA
  CCCCTCGGCCCAAGATCCTACGTTGTAAATGCCACCACCACTGTCCGGAAGACTCAGTCAACAATATCTG
  CAGCACAGATGGGTACTGCTTCACGATGATAGAAGAAGATGACTCTGGAATGCCTGTTGTCACCTCTGGA
  TGTCTAGGACTAGAAGGGTCAGATTTTCAATGTCGTGACACTCCCATTCCTCATCAAAGAAGATCAATTG
  AATGCTGCACAGAAAGGAATGAGTGTAATAAAGACCTCCACCCCACTCTGCCTCCTCTCAAGGACAGAGA
  TTTTGTTGATGGGCCCATACACCACAAGGCCTTGCTTATCTCTGTGACTGTCTGTAGTTTACTCTTGGTC
  CTCATTATTTTATTCTGTTACTTCAGGTATAAAAGACAAGAAGCCCGACCTCGGTACAGCATTGGGCTGG
  AGCAGGACGAGACATACATTCCTCCTGGAGAGTCCCTGAGAGACTTGATCGAGCAGTCTCAGAGCTCGGG
  AAGTGGATCAGGCCTCCCTCTGCTGGTCCAAAGGACAATAGCTAAGCAAATTCAGATGGTGAAGCAGATT
  GGAAAAGGCCGCTATGGCGAGGTGTGGATGGGAAAGTGGCGTGGAGAAAAGGTGGCTGTGAAAGTGTTCT
  TCACCACGGAGGAAGCCAGCTGGTTCCGAGAGACTGAGATATATCAGACGGTCCTGATGCGGCATGAGAA
  TATTCTGGGGTTCATTGCTGCAGATATCAAAGGGACTGGGTCCTGGACTCAGTTGTACCTCATCACAGAC
  TATCATGAAAACGGCTCCCTTTATGACTATCTGAAATCCACCACCTTAGACGCAAAGTCCATGCTGAAGC
  TAGCCTACTCCTCTGTCAGCGGCCTATGCCATTTACACACGGAAATCTTTAGCACTCAAGGCAAGCCAGC
  AATCGCCCATCGAGACTTGAAAAGTAAAAACATCCTGGTGAAGAAAAATGGAACTTGCTGCATAGCAGAC
  CTGGGCTTGGCTGTCAAGTTCATTAGTGACACAAATGAGGTTGACATCCCACCCAACACCCGGGTTGGCA
  CCAAGCGCTATATGCCTCCAGAAGTGCTGGACGAGAGCTTGAATAGAAACCATTTCCAGTCCTACATTAT
  GGCTGACATGTACAGCTTTGGACTCATCCTCTGGGAGATTGCAAGGAGATGTGTTTCTGGAGGTATAGTG
  GAAGAATACCAGCTTCCCTATCACGACCTGGTGCCCAGTGACCCTTCTTATGAGGACATGAGAGAAATTG
  TGTGCATGAAGAAGTTACGGCCTTCATTCCCCAATCGATGGAGCAGTGATGAGTGTCTCAGGCAGATGGG
  GAAGCTTATGACAGAGTGCTGGGCGCAGAATCCTGCCTCCAGGCTGACGGCCCTGAGAGTTAAGAAAACC
  CTTGCCAAAATGTCAGAGTCCCAGGACATTAAACTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR208067 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MLLRSSGKLNVGTKKEDGESTAPTPRPKILRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGMPVVTSG
  CLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKDRDFVDGPIHHKALLISVTVCSLLLV
  LIILFCYFRYKRQEARPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQI
  GKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITD
  YHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIAD
  LGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEIARRCVSGGIV
  EEYQLPYHDLVPSDPSYEDMREIVCMKKLRPSFPNRWSSDECLRQMGKLMTECWAQNPASRLTALRVKKT
  LAKMSESQDIKL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007560
• ORF Size: 1509 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007560.1, NM_007560.2, NM_007560.3, NM_007560.4, NP_031586.1
• RefSeq Size: 5376
• RefSeq ORF: 1509
• Locus ID: 12167
• MW: 56.9 kDa
• Gene Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]