Parp2 (NM_009632) Mouse Tagged ORF Clone

CAT#: MR208862L4

Lenti ORF clone of Parp2 (mGFP-tagged) - Mouse poly (ADP-ribose) polymerase family, member 2 (Parp2)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Parp2
• Synonyms: ADPRT-2; Adprt2; Adprtl2; ARTD2; Aspartl2; C78626; mPARP-2; pADPRT-2; PARP-2
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR208862).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_009632
• ORF Size: 1677 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009632.2, NP_033762.1
• RefSeq Size: 1834
• RefSeq ORF: 1680
• Locus ID: 11546
• Gene Summary: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. [UniProtKB/Swiss-Prot Function]