Plk3 (NM_013807) Mouse Tagged ORF Clone
CAT#: MR209747
- TrueORF®
Plk3 (Myc-DDK-tagged) - Mouse polo-like kinase 3 (Drosophila) (Plk3)
"NM_013807" in other vectors (4)
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Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Plk3 |
Synonyms | Cnk; Fnk; PLK-3; PRK |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR209747 representing NM_013807
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCCCGCCGCCGGCTTCTTGTCTCCGCGCCCCTTCCCGCGCGCGGCTGCCCCGTCCGCGCCCCCCG CCGGCCCGGGGCCGCCTGCCAATGCCTCCCCGCGATCGGAACCTGAGGTGCTGGCCGGGCCACGGGCGCC GGATCCTCCTGGTCGCCTCATCACCGACCCTCTCAGCGGCCGTACCTACACCAAGGGTCGCTTGTTGGGC AAGGGGGGCTTCGCACGCTGCTATGAAGCCACTGACACCGAGTCTGGTATAGCCTACGCGGTCAAAGTCA TCCCACAGAGTCGCGTCGCCAAGCCGCATCAGCGCGAGAAGATCCTAAATGAGATAGAGTTGCACCGAGA CCTACAGCACCGCCATATCGTTCGCTTTTCACATCATTTCGAGGATGCTGACAACATATACATTTTCCTG GAGCTCTGTAGCCGAAAGTCCCTGGCCCACATCTGGAAGGCCCGACACACCCTGTTGGAACCAGAGGTTC GCTACTACCTGCGCCAGATCCTTTCTGGCCTCAAGTACTTGCACCAGAGGGGTATCTTACACAGAGATCT CAAGCTGGGAAATTTTTTCATCACGGATAACATGGAACTGAAGGTGGGGGATTTTGGGCTGGCAGCTCGA TTAGAGCCCCCAGAGCAGAGGAAAAAGACCATCTGTGGCACTCCCAACTACGTGGCTCCAGAAGTGCTGC TGAGACAGGGCCATGGCCCCGAGGCAGATGTGTGGTCGCTTGGTTGTGTCATGTACACGCTCCTGTGTGG GAGCCCCCCATTTGAGACTGCTGACCTGAAGGAGACATACCGCTGCATCAAGCAGGTTCATTACACGCTA CCTGCCAGCCTCTCCCTGCCTGCCCGGCAGCTCCTGGCTGCCATCCTCCGAGCTTCACCCAGAGACCGCC CTTCCATTGAACAGATTTTACGCCATGACTTCTTTACGAAGGGCTACACCCCTGATCGGCTCCCGGTCAG CAGCTGTGTGACAGTCCCAGATCTGACACCCCCCAACCCTGCGAGGAGTCTGTTTGCCAAAGTTACCAAG AGCCTGTTTGGCAGGAAAAAGAACAAGAATAAGAACCATTCTGAGGACCAGGATAATGTCTCCTGCTTGG TGAGTGGCCTCATGCGCACATCCATCGGTCATCCAGATGTCAGGCCGGAGGCTCCTGTAGTTTCAGGCCA GGCCCCTGCCAGCTTGGTAGAGACAGCTGCCGAGGACAGCTCGCCCCGTGGGACACTGGCCAGCAGTGGA GATGGGTTTGAAGAAGGTTTGACTGTGGCCACAGTGGTAGAGTCTGCCCTCTGTGCACTGAGAAACTGTG TGGCCTTCATGCCCCCAGCCGAACAGAACCCAGCCCCGCTGGCACAGCCAGAGCCTCTGGTGTGGGTCAG CAAGTGGGTTGACTACTCCAACAAGTTTGGCTTTGGCTATCAGCTGTCCAGCCGCCGTGTAGCCGTGCTC TTCAATGATGGCACACACATGGCCCTGTCAGCCAATAGGAAGACGGTGCACTACAACCCCACCAGCACGA AGCACTTCTCCTTCTCCATGGGTTCTGTGCCCCGAGCTCTGCAGCCTCAGCTGGGCATCCTGCGGTATTT TGCGTCCTACATGGAACAGCACCTCATGAAGGGTGGAGATCTGCCCAGTGTGGAAGAGGCGGAGGTGCCT GCCCCACCCTTGCTGCTGCAGTGGGTCAAGACTGACCAGGCCCTCCTCATGCTGTTCAGTGATGGCACTG TCCAGGTGAACTTCTACGGGGACCACACGAAGCTGATCCTCAGTGGCTGGGAGCCTCTCCTTGTGACCTT CGTGGCCCGCAATCGCAGTGCTTGTACTTACCTCGCTTCCCACCTCCGGCAGCTGGGCTGCTCCCCAGAC TTGCGGCAGCGACTGCGCTACGCTCTGCGCCTGCTCAGGGACCAAAGCCCTGCT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR209747 representing NM_013807
Red=Cloning site Green=Tags(s) MEPAAGFLSPRPFPRAAAPSAPPAGPGPPANASPRSEPEVLAGPRAPDPPGRLITDPLSGRTYTKGRLLG KGGFARCYEATDTESGIAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFL ELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITDNMELKVGDFGLAAR LEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTL PASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTPDRLPVSSCVTVPDLTPPNPARSLFAKVTK SLFGRKKNKNKNHSEDQDNVSCLVSGLMRTSIGHPDVRPEAPVVSGQAPASLVETAAEDSSPRGTLASSG DGFEEGLTVATVVESALCALRNCVAFMPPAEQNPAPLAQPEPLVWVSKWVDYSNKFGFGYQLSSRRVAVL FNDGTHMALSANRKTVHYNPTSTKHFSFSMGSVPRALQPQLGILRYFASYMEQHLMKGGDLPSVEEAEVP APPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLLVTFVARNRSACTYLASHLRQLGCSPD LRQRLRYALRLLRDQSPA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_013807 |
ORF Size | 1944 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_013807.2, NM_013807.3, NP_038835.2 |
RefSeq Size | 2474 |
RefSeq ORF | 1947 |
Locus ID | 12795 |
MW | 72.3 kDa |
Gene Summary | This gene encodes a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal catalytic domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases have primarily been implicated in cell cycle regulation. In mouse, this protein that has been reported to localize to the nucleolus during interphase but is undetectable during mitosis, following nucleolus dissociation during prophase. The protein relocalizes to the nucleolus just prior to cytokinesis and peak levels are detected during G1 of interphase. This gene has been implicated in regulation of entry into S phase, with RNAi-induced depletion resulting in failure to re-enter the cell cycle. Mice deficient for this gene exhibit increased weight and tumor development at advanced age. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC205095 | Plk3 (untagged) - Mouse polo-like kinase 3 (Drosophila) (Plk3), (10ug) |
USD 210.00 |
|
MG209747 | Plk3 (GFP-tagged) - Mouse polo-like kinase 3 (Drosophila) (Plk3) |
USD 750.00 |
|
MR209747L3 | Lenti ORF clone of Plk3 (Myc-DDK-tagged) - Mouse polo-like kinase 3 (Drosophila) (Plk3) |
USD 880.00 |
|
MR209747L4 | Lenti ORF clone of Plk3 (mGFP-tagged) - Mouse polo-like kinase 3 (Drosophila) (Plk3) |
USD 880.00 |
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