Tshr (NM_011648) Mouse Tagged ORF Clone

CAT#: MR210536

Tshr (Myc-DDK-tagged) - Mouse thyroid stimulating hormone receptor (Tshr), transcript variant 1

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Tshr
• Synonyms: AI481368; hypothroid; hyt; pet
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR210536 representing NM_011648
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC
  GCCC
  
  ATGAGGCCAGGGTCCCTGCTGCTGCTTGTTCTGCTGCTCGCCCTGTCCAGGAGCCTGCGGGGCAAAGAGT
  GTGCGTCTCCACCCTGTGAGTGTCACCAGGAGGACGACTTCAGAGTCACCTGCAAGGAGCTCCACCGAAT
  CCCCAGCCTGCCGCCCAGCACCCAGACTCTGAAGCTCATCGAGACTCATCTGAAGACCATACCCAGTCTT
  GCATTTTCGAGTCTGCCCAATATTTCCAGGATCTATTTATCTATAGATGCAACTCTGCAGCGGCTGGAAC
  CACATTCTTTCTACAATTTGAGTAAAATGACTCACATAGAAATCCGGAACACCAGAAGCTTAACCTATAT
  AGACCCTGATGCCTTGACAGAGCTCCCCTTGCTCAAGTTTCTTGGCATTTTCAATACTGGACTTAGAATA
  TTCCCTGACTTGACCAAAATTTATTCCACGGACATATTCTTTATACTTGAAATCACAGACAACCCTTACA
  TGACTTCGGTCCCTGAAAACGCATTCCAGGGCCTATGCAATGAAACCTTGACCCTGAAACTGTACAACAA
  TGGATTTACTTCAGTCCAAGGACATGCTTTCAATGGAACAAAGCTGGATGCTGTTTACCTAAACAAGAAT
  AAATACCTGACAGCTATAGACAACGATGCCTTTGGAGGAGTATACAGTGGACCAACTTTGCTAGATGTGT
  CTTCCACCAGCGTCACTGCCCTTCCTTCCAAAGGCCTGGAGCACCTCAAAGAACTGATCGCAAAAGACAC
  CTGGACTCTCAAAAAGCTCCCGCTGTCGTTGAGTTTCCTCCACCTCACTCGGGCTGACCTCTCTTACCCG
  AGCCACTGCTGCGCTTTTAAGAACCAGAAGAAAATCAGGGGAATCCTGGAGTCTTTGATGTGTAATGAGA
  GCAGTATCCGGAACCTTCGTCAAAGGAAATCAGTGAACATCTTGAGGGGTCCCATCTACCAGGAATATGA
  AGAAGATCCGGGTGACAACAGTGTTGGGTACAAACAAAACTCCAAGTTCCAGGAGAGCCCAAGCAACTCT
  CACTATTACGTCTTCTTTGAAGAACAAGAGGATGAGGTCGTTGGTTTCGGCCAAGAGCTCAAAAATCCTC
  AGGAAGAGACTCTCCAAGCCTTCGAGAGCCACTATGACTACACGGTGTGTGGGGACAACGAGGACATGGT
  GTGTACCCCCAAGTCGGACGAGTTTAACCCCTGTGAAGATATCATGGGCTACAGGTTCCTGAGAATCGTG
  GTGTGGTTTGTCAGTCTGCTGGCTCTCCTGGGCAATATCTTCGTCCTGCTCATTCTGCTAACCAGCCACT
  ACAAATTGACCGTGCCGCGGTTCCTCATGTGCAACTTGGCCTTTGCAGATTTCTGCATGGGGGTATACCT
  GCTTCTCATTGCCTCTGTAGACCTGTACACACACTCTGAGTACTACAACCACGCCATCGACTGGCAGACG
  GGCCCTGGGTGCAACACGGCTGGCTTCTTCACTGTTTTCGCCAGTGAGTTATCAGTGTACACACTGACGG
  TCATCACCCTGGAGCGATGGTACGCCATCACCTTCGCCATGCGCCTGGATAGGAAGATCCGCCTCAGGCA
  CGCGTACACCATCATGGCTGGGGGCTGGGTTTCCTGCTTCCTTCTCGCCCTGCTCCCGATGGTGGGAATC
  AGCAGCTATGCCAAGGTCAGCATCTGCCTGCCAATGGACACCGACACCCCTCTTGCACTCGCATACATTG
  TCCTCGTTCTGCTGCTCAATGTTGTTGCCTTTGTTGTCGTCTGTTCCTGCTATGTGAAGATCTACATCAC
  GG[AT]CCGAAATCCCCAGTACAACCCTCGAGATAAAGACACCAAGATTGCCAAGAGGATGGCTGTGTTG
  ATCTTCACTGACTTCATGTGCATGGCGCCCATCTCCTTCTATGCGCTGTCGGCACTTATGAACAAGCCTC
  TAATCACTGTTACTAACTCCAAAATCTTGTTGGTTCTCTTCTACCCCCTCAACTCCTGTGCCAATCCGTT
  TCTCTATGCTATTTTCACCAAGGCCTTCCAGAGGGACGTGTTCATCCTGCTCAGCAAGTTTGGCATCTGC
  AAACGCCAGGCCCAGGCCTATCAGGGTCAGAGAGTCTGTCCCAACAATAGCACTGGTATTCAGATCCAAA
  AGATTCCCCAGGACACGAGGCAGAGTCTCCCCAACATGCAAGATACCTATGAACTGCTTGGAAACTCCCA
  GCTAGCTCCAAAACTGCAGGGACAAATCTCAGAAGAGTATAAGCAAACAGCCTTG
  
  ACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGA
  TTACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR210536 representing NM_011648
  Red=Cloning site Green=Tags(s)
  
  MRPGSLLLLVLLLALSRSLRGKECASPPCECHQEDDFRVTCKELHRIPSLPPSTQTLKLIETHLKTIPSL
  AFSSLPNISRIYLSIDATLQRLEPHSFYNLSKMTHIEIRNTRSLTYIDPDALTELPLLKFLGIFNTGLRI
  FPDLTKIYSTDIFFILEITDNPYMTSVPENAFQGLCNETLTLKLYNNGFTSVQGHAFNGTKLDAVYLNKN
  KYLTAIDNDAFGGVYSGPTLLDVSSTSVTALPSKGLEHLKELIAKDTWTLKKLPLSLSFLHLTRADLSYP
  SHCCAFKNQKKIRGILESLMCNESSIRNLRQRKSVNILRGPIYQEYEEDPGDNSVGYKQNSKFQESPSNS
  HYYVFFEEQEDEVVGFGQELKNPQEETLQAFESHYDYTVCGDNEDMVCTPKSDEFNPCEDIMGYRFLRIV
  VWFVSLLALLGNIFVLLILLTSHYKLTVPRFLMCNLAFADFCMGVYLLLIASVDLYTHSEYYNHAIDWQT
  GPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHAYTIMAGGWVSCFLLALLPMVGI
  SSYAKVSICLPMDTDTPLALAYIVLVLLLNVVAFVVVCSCYVKIYITXXRNPQYNPRDKDTKIAKRMAVL
  IFTDFMCMAPISFYALSALMNKPLITVTNSKILLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGIC
  KRQAQAYQGQRVCPNNSTGIQIQKIPQDTRQSLPNMQDTYELLGNSQLAPKLQGQISEEYKQTAL
  
  TRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: AscI-NotI Cloning Scheme for this gene
• ACCN: NM_011648
• ORF Size: 2295 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011648.1, NM_011648.2, NM_011648.3, NM_011648.4, NM_011648.5, NP_035778.3
• RefSeq Size: 4332
• RefSeq ORF: 2295
• Locus ID: 22095
• MW: 87 kDa
• Gene Summary: Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5). [UniProtKB/Swiss-Prot Function]