Adam8 (NM_007403) Mouse Tagged ORF Clone

CAT#: MR210842

Adam8 (Myc-DDK-tagged) - Mouse a disintegrin and metallopeptidase domain 8 (Adam8)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adam8
• Synonyms: ADAM 8; CD156; CD156a; E430039A18Rik; MS2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR210842 representing NM_007403
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTTGGCCTCTGGCTGCTCAGCGTCTTATGGACACCAGCAGTAGCCCCTGGACCTCCTTTGCCCCATG
  TGAAACAGTATGAAGTGGTTTGGCCTCGGCGCCTAGCTGCATCCCGCTCCCGCAGAGCCCTGCCCTCCCA
  CTGGGGCCAGTACCCAGAGAGTCTGAGCTATGCTCTTGGGACCAGCGGGCACGTTTTCACCCTGCACCTT
  CGAAAGAACAGGGACCTGCTGGGCTCAAGCTACACAGAGACCTACTCAGCTGCCAATGGCTCTGAGGTGA
  CAGAGCAACTGCAGGAGCAGGACCATTGCCTCTACCAAGGCCATGTGGAAGGGTACGAGGGCTCAGCTGC
  CAGTATTAGCACCTGTGCTGGCCTCAGGGGCTTTTTCCGAGTTGGGTCCACTGTCCACTTGATTGAGCCT
  CTGGATGCTGATGAAGAGGGGCAACATGCGATGTATCAGGCAAAGCATCTGCAACAGAAGGCTGGGACCT
  GTGGGGTCAAAGATACCAACCTGAATGACCTAGGGCCTCGGGCATTAGAAATATACAGGGCTCAGCCACG
  GAACTGGCTGATACCCAGAGAAACCCGCTATGTGGAGTTGTATGTGGTTGCAGACAGCCAAGAGTTCCAG
  AAGTTGGGGAGCAGAGAGGCCGTGCGCCAGCGAGTGCTGGAGGTTGTAAACCACGTGGACAAGCTTTATC
  AGGAACTCAGTTTTCGAGTTGTCCTGGTGGGCCTGGAGATCTGGAACAAGGACAAATTCTACATCAGCCG
  CTATGCCAACGTGACACTGGAGAACTTCTTGTCCTGGAGGGAACAGAACTTGCAAGGGCAGCACCCACAT
  GACAACGTGCAACTTATCACGGGGGTTGATTTCATTGGGAGCACTGTTGGACTGGCTAAGGTGTCTGCCC
  TGTGTTCCCGTCACTCCGGAGCTGTGAATCAGGACCACTCCAAGAACTCCATTGGTGTAGCCTCCACCAT
  GGCCCATGAGCTGGGCCACAACCTGGGCATGAGCCATGATGAGGACATTCCAGGATGCTACTGTCCTGAA
  CCACGGGAGGGTGGTGGCTGCATCATGACCGAAAGCATCGGCTCCAAGTTCCCCAGGATATTCAGCAGGT
  GTAGCAAGATTGACCTAGAGTCATTCGTGACAAAACCCCAGACAGGCTGCCTGACCAATGTTCCAGATGT
  CAACCGGTTCGTGGGTGGCCCTGTGTGTGGAAACCTGTTTGTGGAGCATGGAGAGCAGTGTGACTGTGGC
  ACACCTCAGGACTGTCAAAACCCCTGCTGCAATGCCACCACTTGCCAGCTGGTCAAGGGGGCAGAGTGTG
  CCAGTGGTACCTGTTGTCATGAATGCAAGGTGAAGCCAGCTGGAGAGGTGTGTCGTCTCAGTAAGGACAA
  ATGTGACCTGGAGGAGTTCTGTGATGGCCGGAAGCCAACATGTCCCGAAGATGCCTTCCAACAGAATGGC
  ACTCCCTGCCCAGGGGGCTACTGCTTTGATGGGAGCTGTCCCACCCTGGCACAGCAGTGCCGGGATCTGT
  GGGGGCCAGGTGCTCGGGTAGCAGCCGACTCCTGCTATACCTTTAGCATCCCTCCGGGCTGCAATGGGAG
  GATGTACTCTGGCAGGATCAACCGGTGTGGAGCGCTGTACTGTGAGGGAGGCCAGAAGCCCCTTGAACGC
  TCCTTCTGCACTTTCTCCTCCAACCATGGAGTCTGCCATGCTCTTGGCACAGGCAGCAACATTGACACCT
  TTGAGCTGGTATTGCAGGGCACCAAGTGCGAGGAGGGAAAGGTTTGCATGGATGGAAGCTGCCAGGACCT
  CCGTGTATACAGATCTGAAAACTGCTCTGCTAAATGCAACAACCATGGGGTATGCAACCACAAGAGGGAG
  TGCCACTGTCACAAGGGCTGGGCACCACCCAACTGTGTACAGCGGCTGGCAGATGTATCAGATGAACAAG
  CAGCGTCTACGAGCCTCCCAGTCAGTGTGGTTGTGGTCTTGGTGATCCTGGTGGCTGCGATGGTCATCGT
  GGCAGGCATCGTCATCTACCGAAAGGCTCCGAGACAAATCCAGAGGAGGAGTGTGGCACCCAAGCCTATC
  TCGGGGCTCTCCAACCCCCTATTCTACACAAGGGACAGCAGCCTGCCAGCTAAGAACAGGCCTCCAGACC
  CTTCTGAGACAGTTTCTACCAACCAGCCCCCAAGACCCATAGTGAAACCAAAGAGGCCTCCCCCTGCACC
  TCCAGGTGCTGTGTCCAGTTCACCACTCCCAGTTCCTGTTTATGCCCCAAAGATACCAAATCAGTTTAGA
  CCTGATCCTCCCACCAAGCCCCTCCCAGAGCTGAAACCCAAGCAGGTCAAGCCAACCTTTGCACCCCCGA
  CACCACCAGTCAAGCCCGGGACTGGAGGGACGGTGCCTGGAGCAACTCAGGGAGCTGGTGAGCCAAAGGT
  TGCTCTGAAGGTCCCCATCCAGAAGAGG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR210842 representing NM_007403
  Red=Cloning site Green=Tags(s)
  
  MLGLWLLSVLWTPAVAPGPPLPHVKQYEVVWPRRLAASRSRRALPSHWGQYPESLSYALGTSGHVFTLHL
  RKNRDLLGSSYTETYSAANGSEVTEQLQEQDHCLYQGHVEGYEGSAASISTCAGLRGFFRVGSTVHLIEP
  LDADEEGQHAMYQAKHLQQKAGTCGVKDTNLNDLGPRALEIYRAQPRNWLIPRETRYVELYVVADSQEFQ
  KLGSREAVRQRVLEVVNHVDKLYQELSFRVVLVGLEIWNKDKFYISRYANVTLENFLSWREQNLQGQHPH
  DNVQLITGVDFIGSTVGLAKVSALCSRHSGAVNQDHSKNSIGVASTMAHELGHNLGMSHDEDIPGCYCPE
  PREGGGCIMTESIGSKFPRIFSRCSKIDLESFVTKPQTGCLTNVPDVNRFVGGPVCGNLFVEHGEQCDCG
  TPQDCQNPCCNATTCQLVKGAECASGTCCHECKVKPAGEVCRLSKDKCDLEEFCDGRKPTCPEDAFQQNG
  TPCPGGYCFDGSCPTLAQQCRDLWGPGARVAADSCYTFSIPPGCNGRMYSGRINRCGALYCEGGQKPLER
  SFCTFSSNHGVCHALGTGSNIDTFELVLQGTKCEEGKVCMDGSCQDLRVYRSENCSAKCNNHGVCNHKRE
  CHCHKGWAPPNCVQRLADVSDEQAASTSLPVSVVVVLVILVAAMVIVAGIVIYRKAPRQIQRRSVAPKPI
  SGLSNPLFYTRDSSLPAKNRPPDPSETVSTNQPPRPIVKPKRPPPAPPGAVSSSPLPVPVYAPKIPNQFR
  PDPPTKPLPELKPKQVKPTFAPPTPPVKPGTGGTVPGATQGAGEPKVALKVPIQKR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007403
• ORF Size: 2478 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007403.1, NM_007403.2, NM_007403.3, NP_031429.1
• RefSeq Size: 3034
• RefSeq ORF: 2481
• Locus ID: 11501
• MW: 90.5 kDa
• Gene Summary: This gene encodes a member of the Adam family of proteins that contain the disintegrin and metalloprotease domains. The encoded protein is localized to the cell surface, where it is involved in the remodeling of extracellular matrix and cell migration. Mice lacking the encoded protein display persistent inflammation upon treatment with allergens. Alternative splicing of this gene results in multiple variants. [provided by RefSeq, Mar 2015]