Adamts4 (NM_172845) Mouse Tagged ORF Clone

CAT#: MR210929

Adamts4 (Myc-DDK-tagged) - Mouse a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Adamts4
• Synonyms: ADAM-TS4; ADAMTS-2; ADMP-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR210929 representing NM_172845
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCCCAGATGGGCTTGCATCCCAGGAGGGGCTTGACTGGGCACTGGCTGCGAAGATTCCAACCCTGCT
  TGCCGCTTCACACTGTGCAGTGGCGGAGGCTGCTGCTGCTGGCCTTCCTCCTGTCCTTAGCGTGGCCCGC
  CAGCCCCCTCCCCCGGGAGGAGGAGATCGTGTTTCCAGAGAAGCTCAATGGCAGTAGCATCCTACCTGGA
  TCAGGCGTTCCTGCCAGGCTGCTGTACCGATTGCCAGCCTTTGGGGAGATGTTGCTACTAGAACTAGAAC
  AGGACCCTGGGGTGCAGGTAGAGGGTTTGACTGTACAGTACCTGGGCCAGGCACCTGAGATGCTGGGTGG
  GGCAGAGCCAGGTACCTACCTGACTGGCACCATCAATGGAGATCCGGAGTCGGTGGCATCTCTGCACTGG
  GACGGGGGAGCCCTATTAGGGGTACTGCAGTACCGTGGGGCCGAACTCCACCTCCAGCCTCTGGAAGGAG
  GCGCCCTTAACTCTGCTGGGGGACCGGGGGCTCACATCCTACGCCGGAAGAGTCCTGCCAGCAGCCAAGG
  TCCCATGTGCACCGTCAAGGCTCCTTCTGGGAGCCCAAGTCCCATTTCCCGCAGAACCAAGCGCTTCGCT
  TCTCTGAGTAGATTCGTGGAGACACTGGTGGTAGCAGATGACAAGATGGCAGCATTCCATGGTACAGGGT
  TAAAGCGCTACCTGCTGACGGTTATGGCAGCCGCCGCTAAAGCCTTTAAACACCCAAGCATCCGAAACCC
  TGTCAACTTGGTGGTGACGCGCCTGGTGATCCTGGGGTCCGGCCAGGAAGGGCCCCAAGTGGGGCCAAGT
  GCCGCCCAGACCCTACGCAGCTTCTGCACCTGGCAGCGGGGCCTCAACACCCCTAACGACTCAGATCCTG
  ACCACTTTGACACAGCCATTCTGTTCACCCGGCAGGACCTGTGTGGGGTCTCCACTTGTGACACCCTGGG
  TATGGCTGATGTGGGCACAGTGTGTGATCCAGCTAGGAGCTGTGCTATTGTGGAAGATGATGGGCTCCAG
  TCAGCCTTCACTGCTGCTCATGAACTGGGCCATGTCTTCAACATGCTCCATGATAACTCCAAGCCATGCA
  CTAACTTGAATGGGCAGGGGGGTTCCTCTCGCCATGTCATGGCTCCTGTCATGGCCCATGTGGACCCTGA
  AGAGCCCTGGTCGCCCTGCAGTGCCCGATTCATCACTGACTTCCTGGACAATGGTTATGGGCACTGCCTC
  TTAGACAAACCGGAGGCTCCCCTCCATCTACCAGCGACTTTTCCTGGCAAGGACTATGACGCTGACCGCC
  AATGCCAACTGACCTTCGGTCCTGACTCAAGCCATTGTCCACAGCTGCCACCGCCCTGTGCTGCCCTCTG
  GTGCTCTGGCCACCTCAATGGCCATGCCATGTGCCAGACGAAGCACTCACCTTGGGCTGATGGCACTCCC
  TGCGGGTCTTCACAGGCCTGCATGGGTGGCCGCTGTCTGCACGTGGACCAGCTCAAGGACTTCAATGTTC
  CTCAGGCTGGCGGCTGGGGCCCCTGGGGACCATGGGGTGACTGCTCCAGGACTTGTGGGGGTGGTGTCCA
  GTTCTCCTCCCGGGATTGCACGAGGCCCGTCCCCCGGAACGGTGGCAAGTATTGTGAGGGCCGCCGGACT
  CGCTTCCGGTCCTGCAACACGGAGAACTGCCCACACGGCTCAGCATTGACCTTCCGTGAAGAGCAGTGTG
  CTGCCTACAACCACCGAACCGACCTCTTCAAGAGCTTTCCAGGGCCCATGGACTGGGTTCCGCGCTACAC
  AGGTGTGGCCCCTCGAGACCAATGCAAACTCACTTGCCAGGCCCGGGCACTGGGCTACTACTACGTACTG
  GAGCCCCGGGTGGCAGATGGGACTCCCTGCTCCCCAGACACCTCCTCTGTCTGTGTCCAGGGCCGCTGTA
  TCCATGCTGGCTGTGACCGGATCATTGGCTCCAAAAAGAAATTTGACAAGTGCATGGTGTGCGGCGGGGA
  TGGCTCTCGCTGCAGCAAGCAGTCGGGCTCCTTCAAAAAATTCAGGTATGGATACAGCGATGTGGTCACG
  ATCCCTGCGGGGGCCACCCATATCCTTGTACGGCAGCAGGGGGGGTCTGGTCTCAAGAGCATCTACCTGG
  CCCTGAAGCTTTCTGACGGTTCTTACGCCCTCAATGGTGAATACACGCTGATGCCCTCCCCAACAGATGT
  GGTTCTTCCTGGGGCAGTCAGCTTGCGCTACAGCGGAGCCACAGCAGCCTCAGAGACACTGTCTGGACAT
  GGGCCGCTGGCCCAGCCCTTGACGCTGCAAGTCCTGGTGGCTGGCAACCCACAGAATGCACGTCTGCGGT
  ACAGTTTCTTTGTCCCGCGGCCAGTCCCTTCAACACCACGCCCTCCTCCCCAAGACTGGCTGCAACGCAG
  GGCAGAGATACTGAAAATCCTTCGGAAGCGTCCCTGGGCAGGCCGGAAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR210929 representing NM_172845
  Red=Cloning site Green=Tags(s)
  
  MSQMGLHPRRGLTGHWLRRFQPCLPLHTVQWRRLLLLAFLLSLAWPASPLPREEEIVFPEKLNGSSILPG
  SGVPARLLYRLPAFGEMLLLELEQDPGVQVEGLTVQYLGQAPEMLGGAEPGTYLTGTINGDPESVASLHW
  DGGALLGVLQYRGAELHLQPLEGGALNSAGGPGAHILRRKSPASSQGPMCTVKAPSGSPSPISRRTKRFA
  SLSRFVETLVVADDKMAAFHGTGLKRYLLTVMAAAAKAFKHPSIRNPVNLVVTRLVILGSGQEGPQVGPS
  AAQTLRSFCTWQRGLNTPNDSDPDHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQ
  SAFTAAHELGHVFNMLHDNSKPCTNLNGQGGSSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCL
  LDKPEAPLHLPATFPGKDYDADRQCQLTFGPDSSHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTP
  CGSSQACMGGRCLHVDQLKDFNVPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRT
  RFRSCNTENCPHGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPRDQCKLTCQARALGYYYVL
  EPRVADGTPCSPDTSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSRCSKQSGSFKKFRYGYSDVVT
  IPAGATHILVRQQGGSGLKSIYLALKLSDGSYALNGEYTLMPSPTDVVLPGAVSLRYSGATAASETLSGH
  GPLAQPLTLQVLVAGNPQNARLRYSFFVPRPVPSTPRPPPQDWLQRRAEILKILRKRPWAGRK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_172845
• ORF Size: 2499 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_172845.3
• RefSeq Size: 3673
• RefSeq ORF: 2502
• Locus ID: 240913
• MW: 91.7 kDa
• Gene Summary: This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active zinc-dependent aggrecanase enzyme that degrades cartilage. [provided by RefSeq, Jul 2016]