Dsc2 (NM_013505) Mouse Tagged ORF Clone

CAT#: MR210942

Dsc2 (Myc-DDK-tagged) - Mouse desmocollin 2 (Dsc2)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Dsc2
• Synonyms: AW228162
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR210942 representing NM_013505
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGGCTGTGGGATCTATGCGCTCCGGGAGCCCTGCCTTCGGCCTGGGACACCTGTTGACCCTTGCGA
  TCCTTGCACTTGCCTCTGATGCCTGTAAAGAAGTCGTCCTCCAGGTCCCCTCTGAACTACCTGCCGAGAA
  ATTTGTTGGCAGAGTGAACCTGATGGACTGCCTTAAATCAGCAGACATAGTTCATCTGAGTGATCCTGAC
  TTCCAAGTCTTAGAAGATGGTTCTGTGTACACAACCAGTTCTGTTGTTTTGTCCTCGGGGCAAAGAAGCT
  TTACTATATGGCTTTTTAGCACAGACAGCCAAGAAGAAAGGGAGATATCTGTCCATTTAGAGGGCCCAGT
  AGAGGTACTAAATAAAAGACCGCATACAGAGAAGGTTCTCAGCCGTGCCAAGAGAAGATGGGCTCCTATC
  CCTTGTTCCATGCTAGAGAATTCATTGGGTCCCTTCCCACTTTTCCTTCAACAGATCCAGTCTGACACAG
  CTCAAAACTATACCATATACTATTCCATCAGAGGTCCAGGAGTTGATAAAGAACCTCTAAACTTATTTTA
  TGTGGAAAGAGATACTGGAAACCTGTATTGCACTGGTCGTGTAGATCGTGAGCAGTATGAGTCCTTTGAG
  CTGACTGCATTTGCAACAACTCCAGATGGGTATACGCCAGAGTACCCACTGCCGCTCCTCATTAAAATAG
  AGGACGAGAACGATAATTACCCGATCTTTACACAGAAACTGTACAGCTTCACAGTTCAGGAAAATAGTCG
  CATTGGTTCTATTGTGGGGGAGGTCTGTGCAACCGACCTGGATGAGCCAGACACAATGCACACTCGCCTG
  AGGTACTCCATCCTGGAGCAGTCGCCTTCTCCACCCATGCTATTTACTATGCATCCCAGCACTGGTGTGA
  TCACTACCACGTCGGCTCAGCTGGACAGAGAGTTAATTGACAAGTACCAGTTGCTAATAAAAGTCCAGGA
  TATGGATGGCCAGTATTTTGGTTTGCACACAACAGCAAAGTGCATCATTACTATTGAAGATGTGAATGAC
  AACCTGCCCACGTTCACTCGCACTACGTATGTGACATCAGTGGAAGAAAATACAGTTAATGTGGAAATCT
  TGCGACTTACTGTTCAGGATAAAGATTTAGTTAACTCACCTAATTGGAGAGCTAATTACACCATTTTGAA
  GGGCAATGAAAATGGAAATTTTAAAATCGTAACAGATCCTAAAACCAATGAAGGCATTCTGTGTGTGATT
  AAGCCTCTGGACTATGAAGAACGGCAACAGGTGACCCTGCAAATTGGAGTAGTTAATGAAGCTCCATACA
  CTAGAGAGGCTAGCTCAAAGTCACCCATGAGCACAGCCACAGTGACTGTCACCGTGACAAATCAGGATGA
  GGGCCCCGAGTGTATCCCTCCAATGCAAACTGTGAGGATTCAAGAAAATGTACCAGTTGGGACTAGAAAT
  GATGGATATAAGGCATATGACCCAGAGACCAGAAGCAGCAGTGGCATAAGGTACAGAAAGTTAAGTGACC
  CAAGAGGGTGGGTCACTGTTAATGAAGATTCAGGATCGATCACTATTTTCCGAGCGTTGGATCGAGAGGC
  TGAGACTGTCAGAAATGGCATTTACAATATTACAGTCCTTGCGTTAGATGCAGATGGGAGAAGCTGTACT
  GGAACTCTGGGAATCATACTTGAAGATGTGAATGATAATGGCCCATTCATACCCAAGCAGACAGTGGTGA
  TATGCAAGGCTACCATGTCCTCTGCTGAAATTGTTGCAGTTGATCTCGATGATCCAGTGAATGGCCCACC
  ATTTGATTTCAGTTTGGAGAGCTCTGATTCGGAAGTTCAGAGGATGTGGAGGCTAACAAGAATCAATGAT
  ACAGCAGCTCGTCTTTCCTATCAGAACGACCCTTCATTTGGATCCTATGCAGTTCCCATTCGAGTTACAG
  ACAGACTTGGTCTGTCCTCAGTAACCACATTGAATGTCCTTGTATGTGACTGCATTACTGAAAGTGACTG
  CACACTCCGCTCTGGAGAAAGGACTGGCTATGCTGATGTGAGACTTGGACCATGGGCCATCCTTGCTATA
  CTGTTGGGCATAGCCTTGCTATTTTGTATCCTGTTTACATTAGTCTGTAGTGTTTCCCGGGCATCAAAAC
  AACAGAAAATTCTTCCTGATGACTTAGCTCAACAGAACCTAATTGTATCAAACACCGAGGCTCCTGGAGA
  TGACAAAGTTTATTCCACAAACGGCTTGACAACTCAAACTATGGGAGCTTCTGGGCAGACAGCTTTCACC
  ACCATGGGAACTGGAGTCAAAAGTGGAGGGCAAGAGACCATTGAGATGGTAAAAGGAGGGCAGCAGACTT
  TGGACTCACGCAGAGGGGCTGGCTATCATCACCATACCCTGGATCCTTGCAGGGGAGGACATGTGGAGGT
  GGACAACTACAGACACACTTACTCAGAGTGGTACAATTTCATTCAGCCCCGACTTGGTGATGAAACCATT
  AGAGGACACACTCTGATTAAAAAT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR210942 representing NM_013505
  Red=Cloning site Green=Tags(s)
  
  MAAVGSMRSGSPAFGLGHLLTLAILALASDACKEVVLQVPSELPAEKFVGRVNLMDCLKSADIVHLSDPD
  FQVLEDGSVYTTSSVVLSSGQRSFTIWLFSTDSQEEREISVHLEGPVEVLNKRPHTEKVLSRAKRRWAPI
  PCSMLENSLGPFPLFLQQIQSDTAQNYTIYYSIRGPGVDKEPLNLFYVERDTGNLYCTGRVDREQYESFE
  LTAFATTPDGYTPEYPLPLLIKIEDENDNYPIFTQKLYSFTVQENSRIGSIVGEVCATDLDEPDTMHTRL
  RYSILEQSPSPPMLFTMHPSTGVITTTSAQLDRELIDKYQLLIKVQDMDGQYFGLHTTAKCIITIEDVND
  NLPTFTRTTYVTSVEENTVNVEILRLTVQDKDLVNSPNWRANYTILKGNENGNFKIVTDPKTNEGILCVI
  KPLDYEERQQVTLQIGVVNEAPYTREASSKSPMSTATVTVTVTNQDEGPECIPPMQTVRIQENVPVGTRN
  DGYKAYDPETRSSSGIRYRKLSDPRGWVTVNEDSGSITIFRALDREAETVRNGIYNITVLALDADGRSCT
  GTLGIILEDVNDNGPFIPKQTVVICKATMSSAEIVAVDLDDPVNGPPFDFSLESSDSEVQRMWRLTRIND
  TAARLSYQNDPSFGSYAVPIRVTDRLGLSSVTTLNVLVCDCITESDCTLRSGERTGYADVRLGPWAILAI
  LLGIALLFCILFTLVCSVSRASKQQKILPDDLAQQNLIVSNTEAPGDDKVYSTNGLTTQTMGASGQTAFT
  TMGTGVKSGGQETIEMVKGGQQTLDSRRGAGYHHHTLDPCRGGHVEVDNYRHTYSEWYNFIQPRLGDETI
  RGHTLIKN
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_013505
• ORF Size: 2544 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013505.1, NM_013505.2, NM_013505.3, NM_013505.4, NP_038533.1
• RefSeq Size: 4416
• RefSeq ORF: 2547
• Locus ID: 13506
• MW: 94.4 kDa
• Gene Summary: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]