Clca2 (NM_178697) Mouse Tagged ORF Clone

CAT#: MR211262

Clca5 (Myc-DDK-tagged) - Mouse chloride channel calcium activated 5 (Clca5)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Clca2
• Synonyms: 4732440A06; AI586120; Clca5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR211262 representing NM_178697
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCCACAGGGACAGCACAGGACCTGTCATCGGGCTGAAACTTGTGACCCTTCTGTTCACCCTAAGTC
  CAGAACTTCTGTTCCTGGGAGCTGGATTGAAGCTGAAAGAGAATGGCTATGATGGATTGCTTGTTGCCAT
  CAATCCCCGGGTACCCGAGGATCTGAAGCTGATTACAAACATTAAGGAAATGATAACCGAAGCTTCCTTT
  TACCTGTTCAATGCGACCAAGAGGAGGGTGTTTTTCAGAAATGTACAGATTTTAGTACCTGCCACTTGGA
  CGGATCATAATTACAGTAGAGTAAGACAAGAATCCTATGACAAGGCAAATGTCATAGTGGCTGAGCAGAG
  TGAGGAACACGGAGATGATCCCTACACCCTACAGCACAGAGGGTGTGGGCAAGAGGGGAGATACATCCAC
  TTCACCCCCAGCTTCCTACTCAACGATGAGTTAGCCGCAGGCTATGGTGCGCGAGGCAGAGTGTTTGTCC
  ACGAGTGGGCCCATCTCCGCTGGGGTGTGTTCGATGAATATAACAACGACAAACCGTTCTACGTGAATGG
  ACGGAATGAGATTCAAGTCACCAGGTGTTCATCTGACATTACAGGCGTTTTTGTGTGTGAAAAGGGCCTC
  TGCCCCCATGAAGACTGCATTATTAGCAAGATTTTTAGGGAAGGATGCACATTCCTCTACAACAGCACCC
  AGAATGCAACTGGATCAATAATGTTCATGCCAAGTTTACCTTCTGTGGTTGAATTCTGTAACGAAAGTAC
  ACACAACCAAGAAGCTCCAAACCTCCAGAACCAAGTGTGCAGCCTCAGAAGCACTTGGGACGTGATCACA
  GCCTCCTCCGACCTGAACCATAGCCTCCCCGTGCATGGGGTTGGACTTCCAGCCCCTCCCACGTTCTCCC
  TCTTGCAGGCTGGTGACCGAGTGGTCTGCTTAGTGATTGATGTGTCCAGGAAGATGGCAGAGGGAGACAG
  ACTGCTCCGACTTCAACAAGCAGCCGAACTGTACTTGATGCAGGTTGTCGAAGCTCACACTTTCGTGGGC
  ATTGTCACTTTTGATAGCAAAGGAGAAATCCGAGCCTCGCTGCAGCAAATTTACAGTGACGATGACCGGA
  AGCTGCTGGTTTCATACCTGCCGACCGCCGTGTCCACTGACGCAGAAACGAACATCTGTGCAGGGGTTAA
  GAAAGGCTTTGAGGTGGTTGAGGAGCGGAATGGAAGAGCTGACGGCTCTGTCCTGATATTAGTGACCAGT
  GGAGCAGATGAACACATTGCCAACTGCCTGCTCACCTCGATGAACAGTGGATCCACCATTCACTCCATGG
  CCCTGGGTTCCTCTGCAGCCAGAAAAGTGGGGGAATTATCACGTCTTACAGGAGGTCTAAAGTTCTTCAT
  TCCAGATAAATTTACTTCTAATGGAATGACTGAAGCTTTCGTTCGAATCTCTTCTGGAACAGGAGACATT
  TTCCAGCAAAGCTTACAGGTTGAGAGCGTGTGCGAAACTGTGCAACCCCAGCACCAGCTGGCGGATACTA
  TGACTGTGGATAGCGCCGTGGGCAATGACACACTTTTTCTAGTCACGTGGCAGACTGGTGGCCCCCCTGA
  GATTGCATTATTGGATCCTAGCGGAAGAAAATACAACACTGGTGACTTTATCATCAACCTGGCCTTTCGG
  ACAGCCAGCCTTAAGATTCCAGGGACAGCTAAGCATGGGCACTGGACTTACACGCTGAACAACACCCACC
  ATTCTCCCCAAGCTCTGAAAGTGACAGTGGCCTCTCGTGCCTCCAGCCTGGCCATGTCCCCAGCCACTCT
  GGAAGCCTTTGTGGAAAGAGACAGCACCTATTTTCCTCAGCCAGTGATCATTTATGCGAATGTGAGGAAA
  GGTCTGCATCCCATTCTCAATGCCACCGTGGTGGCGACAGTGGAACCAGAGGCTGGAGATCCCGTTGTAC
  TGCAACTTTTGGATGGCGGAGCAGGTGCAGATGTTATAAGAAATGATGGGATTTACTCCAGGTATTTTTC
  CTCCTTTGCTGTAAGTGGTAGCTATAGCCTGACAGTGCATGTCCGTCACTCTCCCAGCACAAGCACACTA
  GCCCTCCCTGTCCCAGGAAACCATGCTATGTATGTACCAGGTTACATAACAAACGATAATATTCAAATGA
  ATGCTCCCAAAAACTTGGGCCACAGACCTGTGAAGGAGAGGTGGGGCTTCAGTCGAGTGAGCTCGGGAGG
  CTCCTTCTCCGTGCTGGGAGTCCCAGACGGCCCCCACCCTGACATGTTTCCACCGTGCAAAATTACTGAC
  CTGGAAGCCATGAAAGTGGAAGACGACGTCGTCCTCTCTTGGACGGCACCTGGGGAAGACTTCGATCAGG
  GGCAAACTACAAGCTATGAAATAAGAATGAGCAGAAGCCTATGGAACATTCGGGATGACTTTGACAATGC
  CATCTTGGTGAATTCGTCAGAGCTAGTTCCTCAGCATGCTGGCACCAGGGAGACATTTACATTCTCACCC
  AAGCTTGTCACCCATGAACTTGATCATGAACTTGCTGAAGATGCACAAGAACCCTACATAGTGTATGTGG
  CCCTGAGAGCCATGGATAGAAGCTCCCTCAGGTCAGCTGTGTCAAACATTGCCCTGGTATCAATGTCTCT
  TCCTCCAAACTCTTCTCCTGTAGTGAGCAGAGATGATCTGATCCTGAAAGGAGTTTTAACAACAGTAGGT
  TTGATAGCAATCCTTTGCCTTATTATGGTTGTAGCACACTGTATTTTTAACAGGAAAAAGAGACCATCAA
  GAAAAGAGAATGAGACAAAATTTCTA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR211262 representing NM_178697
  Red=Cloning site Green=Tags(s)
  
  MTHRDSTGPVIGLKLVTLLFTLSPELLFLGAGLKLKENGYDGLLVAINPRVPEDLKLITNIKEMITEASF
  YLFNATKRRVFFRNVQILVPATWTDHNYSRVRQESYDKANVIVAEQSEEHGDDPYTLQHRGCGQEGRYIH
  FTPSFLLNDELAAGYGARGRVFVHEWAHLRWGVFDEYNNDKPFYVNGRNEIQVTRCSSDITGVFVCEKGL
  CPHEDCIISKIFREGCTFLYNSTQNATGSIMFMPSLPSVVEFCNESTHNQEAPNLQNQVCSLRSTWDVIT
  ASSDLNHSLPVHGVGLPAPPTFSLLQAGDRVVCLVIDVSRKMAEGDRLLRLQQAAELYLMQVVEAHTFVG
  IVTFDSKGEIRASLQQIYSDDDRKLLVSYLPTAVSTDAETNICAGVKKGFEVVEERNGRADGSVLILVTS
  GADEHIANCLLTSMNSGSTIHSMALGSSAARKVGELSRLTGGLKFFIPDKFTSNGMTEAFVRISSGTGDI
  FQQSLQVESVCETVQPQHQLADTMTVDSAVGNDTLFLVTWQTGGPPEIALLDPSGRKYNTGDFIINLAFR
  TASLKIPGTAKHGHWTYTLNNTHHSPQALKVTVASRASSLAMSPATLEAFVERDSTYFPQPVIIYANVRK
  GLHPILNATVVATVEPEAGDPVVLQLLDGGAGADVIRNDGIYSRYFSSFAVSGSYSLTVHVRHSPSTSTL
  ALPVPGNHAMYVPGYITNDNIQMNAPKNLGHRPVKERWGFSRVSSGGSFSVLGVPDGPHPDMFPPCKITD
  LEAMKVEDDVVLSWTAPGEDFDQGQTTSYEIRMSRSLWNIRDDFDNAILVNSSELVPQHAGTRETFTFSP
  KLVTHELDHELAEDAQEPYIVYVALRAMDRSSLRSAVSNIALVSMSLPPNSSPVVSRDDLILKGVLTTVG
  LIAILCLIMVVAHCIFNRKKRPSRKENETKFL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_178697
• ORF Size: 2826 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_178697.1, NM_178697.2, NM_178697.3, NM_178697.4, NM_178697.5, NP_848812.1
• RefSeq Size: 3921
• RefSeq ORF: 2829
• Locus ID: 229933
• MW: 104.1 kDa
• Gene Summary: This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. Mice lacking a functional copy of this gene exhibit increased liver weight and hepatocyte hypertrophy. [provided by RefSeq, Sep 2016]