Mpl (NM_010823) Mouse Tagged ORF Clone

CAT#: MR212144

Mpl (Myc-DDK-tagged) - Mouse myeloproliferative leukemia virus oncogene (Mpl), transcript variant 2

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Mpl
• Synonyms: c-mpl; CD110; hlb219; TPO-R
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR212144 representing NM_010823
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCTCTTGGGCCCTCTTCATGGTCACCTCCTGCCTCCTCTTGGCCCTTCCAAACCAGGCACAAGTCA
  CCAGCCAAGATGTCTTCTTGCTGGCCTTGGGCACAGAGCCCCTGAACTGCTTCTCCCAAACATTTGAGGA
  CCTCACCTGCTTCTGGGATGAGGAAGAGGCAGCACCCAGTGGGACATACCAGCTGCTGTATGCCTACCGA
  GGAGAGAAGCCCCGTGCATGCCCCCTGTATTCCCAGAGTGTGCCCACCTTTGGAACCCGGTATGTGTGCC
  AGTTTCCAGCCCAGGATGAAGTGCGCCTCTTCTTTCCGCTGCACCTCTGGGTGAAGAATGTGTCCCTCAA
  CCAGACTTTGATCCAGCGGGTGCTGTTTGTGGATAGTGTGGGCCTGCCAGCTCCCCCCAGGGTCATCAAG
  GCCAGGGGTGGGAGCCAACCAGGGGAACTTCAGATCCACTGGGAGGCCCCTGCTCCTGAAATCAGTGACT
  TCCTGAGGCATGAACTCCGCTATGGCCCCACGGACTCCAGCAACGCCACTGCCCCCTCCGTCATTCAGCT
  GCTCTCCACAGAAACCTGCTGCCCCACTTTGTGGATGCCGAACCCAGTCCCTGTTCTTGACCAGCCTCCG
  TGTGTTCATCCGACAGCATCCCAACCGCATGGACCAGCTCCATTTCTGACAGTGAAGGGTGGAAGCTGTC
  TCGTCTCAGGCCTCCAGGCTGGCAAATCCTACTGGCTCCAGCTACGCAGCCAACCCGACGGGGTCTCCCT
  TCGTGGCTCCTGGGGACCCTGGTCCTTCCCTGTGACTGTGGATCTTCCAGGAGATGCAGTGACAATTGGA
  CTTCAGTGCTTTACCTTGGATCTGAAGATGGTCACCTGCCAGTGGCAGCAACAAGACCGCACTAGCTCCC
  AAGGCTTCTTCCGCCACAGCAGGACGAGGTGCTGCCCCACAGACAGGGACCCCACCTGGGAGAAATGTGA
  AGAGGAGGAACCGCGTCCAGGATCACAGCCCGCTCTCGTCTCCCGCTGCCACTTCAAGTCACGAAATGAC
  AGTGTTATTCACATCCTTGTAGAGGTGACCACAGCGCAAGGTGCCGTTCACAGCTACCTGGGCTCCCCTT
  TTTGGATCCACCAGGCTGTGCTCCTTCCCACCCCGAGCCTGCACTGGAGGGAGGTCTCAAGTGGAAGGCT
  GGAGTTGGAGTGGCAGCACCAGTCATCTTGGGCAGCTCAAGAGACCTGCTACCAGCTCCGGTACACGGGA
  GAAGGCCGTGAGGACTGGAAGGTGCTGGAGCCATCTCTCGGTGCCCGGGGAGGGACCCTAGAGCTGCGCC
  CCCGAGCTCGCTACAGCTTGCAGCTGCGTGCCAGGCTCAACGGCCCCACCTACCAAGGTCCCTGGAGCGC
  CTGGTCTCCCCCAGCTAGGGTGTCCACGGGCTCCGAGACTGCTTGGATCACCTTGGTGACTGCTCTGCTC
  CTGGTGCTGAGCCTCAGTGCCCTTCTGGGCCTACTGCTGCTAAAGTGGCAATTTCCTGCGCACTACAGGA
  GACTGAGGCATGCTTTGTGGCCCTCGCTTCCAGACCTACACCGGGTCCTAGGCCAGTACCTCAGAGACAC
  TGCAGCCCTAAGTCCTTCTAAGGCCACGGTTACCGATAGCTGTGAAGAAGTGGAACCCAGCCTCCTGGAA
  ATCCTCCCTAAGTCCTCAGAGAGCACTCCTTTACCTCTGTGTCCCTCCCAACCTCAGATGGACTACAGAG
  GACTGCAACCTTGCCTGCGGACCATGCCCCTGTCTGTGTGTCCACCCATGGCTGAGACGGGGTCCTGCTG
  CACCACACACATTGCCAACCACTCCTACCTACCACTAAGCTATTGGCAGCAGCCC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR212144 representing NM_010823
  Red=Cloning site Green=Tags(s)
  
  MPSWALFMVTSCLLLALPNQAQVTSQDVFLLALGTEPLNCFSQTFEDLTCFWDEEEAAPSGTYQLLYAYR
  GEKPRACPLYSQSVPTFGTRYVCQFPAQDEVRLFFPLHLWVKNVSLNQTLIQRVLFVDSVGLPAPPRVIK
  ARGGSQPGELQIHWEAPAPEISDFLRHELRYGPTDSSNATAPSVIQLLSTETCCPTLWMPNPVPVLDQPP
  CVHPTASQPHGPAPFLTVKGGSCLVSGLQAGKSYWLQLRSQPDGVSLRGSWGPWSFPVTVDLPGDAVTIG
  LQCFTLDLKMVTCQWQQQDRTSSQGFFRHSRTRCCPTDRDPTWEKCEEEEPRPGSQPALVSRCHFKSRND
  SVIHILVEVTTAQGAVHSYLGSPFWIHQAVLLPTPSLHWREVSSGRLELEWQHQSSWAAQETCYQLRYTG
  EGREDWKVLEPSLGARGGTLELRPRARYSLQLRARLNGPTYQGPWSAWSPPARVSTGSETAWITLVTALL
  LVLSLSALLGLLLLKWQFPAHYRRLRHALWPSLPDLHRVLGQYLRDTAALSPSKATVTDSCEEVEPSLLE
  ILPKSSESTPLPLCPSQPQMDYRGLQPCLRTMPLSVCPPMAETGSCCTTHIANHSYLPLSYWQQP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_010823
• ORF Size: 1875 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010823.1, NM_010823.2, NM_010823.3, NP_034953.2
• RefSeq Size: 2914
• RefSeq ORF: 1878
• Locus ID: 17480
• MW: 70.2 kDa
• Gene Summary: Receptor for thrombopoietin. May represent a regulatory molecule specific for TPO-R-dependent immune responses. [UniProtKB/Swiss-Prot Function]