Akap8 (NM_019774) Mouse Tagged ORF Clone

CAT#: MR215718L4

Lenti ORF clone of Akap8 (mGFP-tagged) - Mouse A kinase (PRKA) anchor protein 8 (Akap8)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Akap8
• Synonyms: 1200016A02Rik; AA673585; AKAP-8; AKAP95; AU015639
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR215718).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_019774
• ORF Size: 2064 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_019774.4, NP_062748.2
• RefSeq Size: 3695
• RefSeq ORF: 2064
• Locus ID: 56399
• Gene Summary: This gene encodes a member of the A-kinase anchoring protein (AKAP) family. These proteins are characterized by their ability to bind to the R subunit of protein kinase A (PKA) and anchor the protein at different subcellular locations. This protein has been shown to regulate apoptosis and to be involved in palatogenesis. Knockdown of this gene has been associated with altered histone modifications and reduced expression of developmental genes in mouse embryonic stem cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]