F13a1 (NM_001166391) Mouse Tagged ORF Clone
CAT#: MR220954
- TrueORF®
F13a1 (Myc-DDK-tagged) - Mouse coagulation factor XIII, A1 subunit (F13a1), transcript variant 2
"NM_001166391" in other vectors (4)
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Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | F13a1 |
Synonyms | 1200014I03Rik; AI462306; F13a |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR220954 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCAGATACTCCAGCAAGCACCTTTGGGGGGAGGCGAGCAGTCCCGCCCAATAACTCCAATGCTGCAG AAGTGGACCTCCCAACTGAGGAGCTACAAGGCCTGGTGCCAAGGGGTGTCAACCTGAAAGATTACCTGAA TGTCACAGCTGTTCACCTGTTCAAGGAGAGATGGGACAGTAACAAGATTGATCACCACACAGACAAATAT GACAACAATAAGTTGATTGTCCGCAGAGGGCAGACCTTCTACATCCAGATTGACTTCAACCGTCCCTATG ACCCCAGGAAGGATCTCTTCAGAGTGGAATATGTCATTGGTCGCTACCCTCAGGAGAACAAGGGCACCTA CATCCCTGTGCCTGTAGTGAAAGAGCTGCAAAGCGGAAAGTGGGGAGCCAAGGTTATCATGAATGAGGAC CGGTCGGTGCGACTTTCCGTTCAGTCTTCTCCGGAATGCATTGTGGGGAAATTCCGCATGTATGTTGCAG TCTGGACTCCCTATGGCATCCTGCGTACTCGAAGAGACCCAGAAACAGACACATATATTCTCTTCAACCC TTGGTGTGAAGAGGACGCTGTGTATCTGGATGATGAGAAGGAAAGAGAAGAGTACGTCCTGAATGACATT GGAGTGATATTTTATGGGGACTTCAAAGACATCAAGAGCAGAAGCTGGAGCTATGGCCAGTTCGAAGACG GCATCCTGGATACTTGCTTGTATGTGATGGACAAAGCTGAGATGGACCTTTCTGGCAGAGGCAACCCCAT CAAAGTCAGCCGAGTTGGATCAGCAATGGTGAATGCCAAGGATGATGAAGGTGTTCTTGTTGGATCATGG GACAATGTCTATGCCTACGGCATCCCTCCATCAGCCTGGACAGGAAGTGTTGACATTCTACTAGAATACA GAAGCTCGGAAACACCAGTCCGATATGGCCAGTGTTGGGTTTTTGCTGGTGTCTTTAACACATTTTTAAG ATGCCTTGGAATCCCTGCACGAGTCATTACCAATTACTTCTCGGCCCACGACAATGATGCCAATCTGCAA ATGGACATCTTCCTGGAAGAAGATGGGAATGTGAGCTCCAAACTCACCAAGGATTCGGTGTGGAACTACC ACTGCTGGAACGAAGCGTGGATGACAAGGCCTGATCTTCCTGTTGGATTTGGAGGCTGGCAAGCTGTGGA CAGCACACCCCAGGAAAACAGTGATGGCATGTACCGCTGTGGCCCTGCCTCTGTCCAAGCCGTTAAGCAT GGCCATGTCTGCTTCCAGTTTGATGCCCCGTTTGTTTTTGCAGAGGTCAACAGTGATCTTGTTTACATCA CAGCTAAGCAAGATGGCACTCACGTGGTGGAAGCCGTGGATGCCACCCATATCGGGAAGCTAATTGTGAC CAAGCAAATTGGAGGAGATGGCATGCAGGATATCACGGATACTTACAAATTTCAAGAAGGCCAAGAAGAA GAGAGACTAGCCCTTGAAACTGCTCTGATGTATGGAGCCAAGAAGACCCTCAACACTGAAGGTGTTGTCA AATCAAGGTCTGATGTGACCATGAACTTTGATGTGGAAAATGCTGTGCTGGGAAAGGACTTCAAAGTGAC TATCACCTTCCAGAACAATAGCTCCAATCTGTACACCATCCTGGCCTATCTTTCTGGCAACATCACCTTC TACACTGGGGTATCCAAGAAAGAGTTCAAGAAGGAGTCCTTTGAAGAGACGCTGGATCCCTTTTCCTCCA AGAAAAAGGAGGTGCTGGTCAGAGCGGGCGAGTACATGAGCCACCTTCTAGAACAGGGCTTCTTGCACTT CTTCGTCACGGCACGCATCAACGAGTCCAGGGATGTCCTGGCCAAACAAAAGTCCATAATACTGACTATC CCCAAGATCACCATCAAGGTCCGAGGTGCTGCCATGGTTGGCTCTGATATGGTTGTGACTGTTGAGTTCA CTAATCCTTTAAAAGAAACACTACAAAATGTCTGGATTCATTTGGATGGTCCTGGAGTGATGAGACCCAA GAGAAAGGTGTTCCGTGAAATCCGGCCCAACACCACGGTGCAGTGGGAAGAAGTCTGTCGGCCTTGGGTC TCTGGCCATCGGAAGCTGATTGCCAGCATGACCAGTGACTCCCTGAGACATGTGTATGGAGAGCTGGATC TTCAGATTCAAAGACGACCTACTATG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR220954 protein sequence
Red=Cloning site Green=Tags(s) MSDTPASTFGGRRAVPPNNSNAAEVDLPTEELQGLVPRGVNLKDYLNVTAVHLFKERWDSNKIDHHTDKY DNNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVKELQSGKWGAKVIMNED RSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTRRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDI GVIFYGDFKDIKSRSWSYGQFEDGILDTCLYVMDKAEMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSW DNVYAYGIPPSAWTGSVDILLEYRSSETPVRYGQCWVFAGVFNTFLRCLGIPARVITNYFSAHDNDANLQ MDIFLEEDGNVSSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAVKH GHVCFQFDAPFVFAEVNSDLVYITAKQDGTHVVEAVDATHIGKLIVTKQIGGDGMQDITDTYKFQEGQEE ERLALETALMYGAKKTLNTEGVVKSRSDVTMNFDVENAVLGKDFKVTITFQNNSSNLYTILAYLSGNITF YTGVSKKEFKKESFEETLDPFSSKKKEVLVRAGEYMSHLLEQGFLHFFVTARINESRDVLAKQKSIILTI PKITIKVRGAAMVGSDMVVTVEFTNPLKETLQNVWIHLDGPGVMRPKRKVFREIRPNTTVQWEEVCRPWV SGHRKLIASMTSDSLRHVYGELDLQIQRRPTM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001166391 |
ORF Size | 2199 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001166391.1, NP_001159863.1 |
RefSeq Size | 3854 |
RefSeq ORF | 2199 |
Locus ID | 74145 |
MW | 83.2 kDa |
Gene Summary | This gene encodes subunit A of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit B to form a heterotetrameric proenzyme that undergoes thrombin-mediated proteolysis to generate active factor XIIIa. The transglutaminase activity of factor XIIIa is required for the calcium-dependent crosslinking of fibrin, leading to the formation of a clot. Mice lacking the encoded protein display impaired reproduction and reduced survival due to bleeding episodes, hematothorax, hematoperitoneum and subcutaneous hemorrhage. Additionally, mice lacking the encoded protein exhibit impaired wound healing and inadequate healing of myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC221177 | F13a1 (untagged) - Mouse coagulation factor XIII, A1 subunit (F13a1), transcript variant 2, (10ug) |
USD 1,000.00 |
|
MG220954 | F13a1 (GFP-tagged) - Mouse coagulation factor XIII A1 subunit (F13a1) transcript variant 2, (10ug) |
USD 750.00 |
|
MR220954L3 | Lenti ORF clone of F13a1 (Myc-DDK-tagged) - Mouse coagulation factor XIII, A1 subunit (F13a1), transcript variant 2 |
USD 1,092.00 |
|
MR220954L4 | Lenti ORF clone of F13a1 (mGFP-tagged) - Mouse coagulation factor XIII, A1 subunit (F13a1), transcript variant 2 |
USD 880.00 |
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