Abcc6 (NM_018795) Mouse Tagged ORF Clone

CAT#: MR221951

Abcc6 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Abcc6
• Synonyms: Abcc1b; DCC; dyscalc; Dyscalc1; Mrp6
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR221951 representing NM_018795
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAACAGAGGGCGCTCCATGGCCACGCCTGGAGAGCAGTGCGCCGGCCTGAGGGTCTGGAACCAGACAG
  AGCAGGAGCCTGCGGCCTATCACTTGCTCAGCCTGTGCTTTGTGAGAGCCGCCAGCAGCTGGGTGCCCCC
  CATGTACCTCTGGGTCCTCGGCCCCATCTACCTTCTCTACATCCATCGCCATGGCCGGTGCTACCTCCGG
  ATGTCCCACCTCTTCAAAACCAAAATGGTGCTGGGCTTGGCCCTCATCCTTCTGTATACCTTCAACGTGG
  CCGTGCCTCTGTGGAGGATCCACCAGGGCGTGCCCCAGGCCCCAGAGCTTCTAATTCACCCTACTGTGTG
  GCTCACCACCATGAGCTTTGCCACCTTTCTGATCCACATGGAGAGAAGGAAGGGAGTCCGGTCATCCGGG
  GTGTTGTTCGGGTACTGGCTGCTCTGCTGCATCTTGCCAGGAATCAACACTGTGCAGCAGGCCTCTGCAG
  GGAACTTCCGTCAGGAGCCCCTCCACCACCTGGCCACCTACCTGTGCTTGTCCCTGGTGGTGGCTGAGCT
  GGTGCTGTCCTGTCTGGTGGACCAGCCACCCTTCTTCTCGGAAGACTCCCAGCCATTGAATCCGTGTCCA
  GAGGCTGAGGCCTCCTTTCCCTCCAAGGCCATGTTCTGGTGGGCCTCTGGACTGCTATGGAGGGGCTACA
  AAAAGCTGCTGGGACCAAAAGACCTCTGGTCACTTGGGAGAGAAAACTCTTCAGAAGAACTCGTTTCCCA
  GCTGGAAAGAGAATGGAGGAGAAGCTGCAATGGGCTGCCAGGGCACAAAGGGCACAGTAGTGTGGGGGCC
  CCTGAGACAGAGGCCTTCCTGCAGCCAGAGAGGAGTCAGAGGGGCCCACTACTCAGGGCTATCTGGCGCG
  TGTTCCGGTCCACCTTCCTGCTGGGGACCCTCAGCCTGGTCATTAGCGATGCCTTCAGGTTTGCTGTTCC
  CAAGCTCCTCAGTCTGTTTCTGGAGTTCATGGGTGACCGCAACTCCTCGGCGTGGACAGGCTGGCTCCTA
  GCTGTGCTGATGTTCGCGGCAGCCTGCCTACAGACGTTGTTTGAACAGCAGCACATGTACAGAGCCAAGG
  TCCTGCAGATGAGGCTGCGAACAGCCATCACTGGCCTGGTGTACAGAAAGGTCCTGGTCCTGTCCAGTGG
  TTCCAGAAAGTCCAGCGCAGCAGGGGACGTGGTCAACCTGGTGTCGGTGGACATCCAGCGGCTGGCCGAG
  AGCATCATCTACCTCAACGGGCTGTGGCTGCTCTTCCTGTGGATCTTTGTGTGCTTTGTCTACCTGTGGC
  AGCTCCTTGGACCCTCTGCTCTCACAGCCGTTGCTGTCTTCCTGAGCCTCCTCCCTCTGAACTTCTTCAT
  CACCAAGAAGAGGGGCTTCCATCAGGAAGAACAGATGAGGCAGAAGGCCTCCAGAGCACGGCTCACCAGC
  TCCATGCTCAGAACTGTGAGAACCATCAAGTCCCACGGCTGGGAGCATGCCTTCCTGGAGCGACTCCTTC
  ACATCCGGGGCCAGGAGCTCAGCGCCCTGAAGACCTCCACCCTCCTCTTCTCTGTGTCTCTCGTGTCCTT
  CCAAGTGTCTACATTTCTGGTGGCGCTGGTCGTGTTTGCTGTCCACACCCTGGTGGCAGAGGACAATGCC
  ATGGATGCAGAGAAGGCCTTTGTGACGCTCACAGTGCTCAGCATCCTTAACAAAGCCCAGGCCTTCCTCC
  CCTTCTCTGTGCACTGCATCGTTCAGGCTCGAGTGTCCTTTGACCGGCTGGCTGCCTTCCTGTGCCTGGA
  AGAAGTAGACCCCAATGGCATGATCGCGAGTAACTCCAGGCGCTCCTCGAAGGATCGAATTTCTGTACAC
  AATGGCACCTTCGCTTGGTCCCAGGAGAGCCCACCCTGCCTGCACGGGATCAACCTCACCGTGCCCCAGG
  GCTGTCTGCTGGCTGTTGTGGGTCCAGTGGGGGCTGGGAAGTCCTCCCTGCTGTCTGCCCTGCTTGGGGA
  GCTGTTGAAGGTAGAAGGGTCTGTGAGCATTGAGGGTTCCGTGGCTTACGTGCCTCAGGAGGCCTGGGTC
  CAGAATACCTCTGTGGTGGAGAATGTGTGCTTCAGGCAAGAGCTGGACCTGCCCTGGTTGCAGAAAGTTC
  TAGATGCCTGTGCCTTGGGGTCTGATGTGGCCAGCTTCCCTGCAGGAGTTCACACCCCAATAGGGGAGCA
  GGGCATGAATCTTTCTGGGGGCCAGAAGCAGCGGCTGAGCTTGGCTCGGGCTGTGTACAAAAAGGCTGCC
  ATCTACTTGCTGGATGACCCCCTGGCAGCGCTGGATGCCCACGTCAGCCAGCAGGTCTTCAAACAGGTCA
  TCGGGCCCAGTGGATTGCTCCAGGGTACGACTCGGATCCTTGTAACACACACGCTGCACGTCCTGCCCCA
  GGCTGACCGGATCCTGGTGCTGGCCAATGGGACCATCGCAGAGATGGGCTCCTACCAGGACCTTCTGCAA
  AGGAACGGAGCCCTGGTGGGTCTTCTGGATGGAGCCAGACAGCCTGCAGGAACACACGATGCAGCTACCA
  GTGACGACCTCGGAGGCTTTCCTGGAGGTGGGAGGCCCACATGCAGACCAGACAGGCCCAGGCCCACGGA
  GGCAGCCCCTGTGAAGGGCAGGAGCACATCTGAGGTACAGATGGAGGCTTCTCTGGATGACCCTGAGGCC
  ACAGGATTGACAGCAGAAGAGGATAGTGTGCGATATGGCCGGGTGAAGACCACCATATACCTGAGCTACC
  TGCGGGCGGTGGGCACACCCCTCTGTACCTACACCCTGTTCCTCTTCCTCTGCCAGCAAGTGGCATCCTT
  CTCCCAAGGCTACTGGCTGAGCCTTTGGGCCGATGACCCGGTTGTGGATGGGCGGCAGATGCATGCAGCC
  CTGCGTGGCTGGGTCTTTGGGCTCCTTGGCTGTCTGCAAGCCATCGGACTGTTTGCCTCCATGGCTGCGG
  TGTTCCTGGGTGGAGCCCGGGCCTCAGGCCTCCTTTTCCGGAGTCTCCTGTGGGACGTGGCTCGCTCTCC
  CATCGGCTTCTTTGAGCGCACGCCAGTCGGGAACCTGCTGAACCGCTTTTCCAAGGAGACAGACACAGTG
  GATGTGGACATCCCGGACAAGCTGAGGTCCCTTCTGACCTACGCCTTTGGGCTCCTGGAGGTCGGCCTGG
  CAGTGACGATGGCCACGCCTCTGGCCATTGTGGCCATCCTACCTCTCATGGTCCTCTATGCTGGGTTTCA
  GAGCCTCTATGTGGCCACATCTTGCCAGCTGAGACGTCTAGAGTCGGCCCGCTACTCATCTGTGTGTTCC
  CATATGGCTGAGACCTTCCAGGGAAGTCTGGTGGTCAGGGCCTTCCGGGCCCAGGCATCCTTCACGGCTC
  AGCACGATGCTCTCATGGATGAGAACCAGAGGGTCAGTTTCCCGAAACTGGTGGCTGACAGGTGGCTGGC
  TACTAACCTGGAGCTTCTAGGGAATGGCTTGGTATTCGTGGCTGCTACATGTGCTGTGCTGAGCAAGGCT
  CACCTAAGTGCTGGCCTCGTGGGCTTCTCGGTCTCCGCTGCCCTCCAGGTGACACAGACTCTGCAGTGGG
  TGGTCCGCAGCTGGACAGATCTGGAGAACAGCATGGTAGCCGTGGAGCGCGTGCAGGACTACGCTCGCAT
  CCCCAAAGAGGCTCCCTGGAGGCTGCCCACCTGCGCAGCCCAGCCTCTCTGGCCTTGTGGGGGACAGATT
  GAGTTCCGGGACTTTGGGCTCAGACACCGACCAGAGCTGCCCTTGGCTGTGCAGGGAGTGTCCCTGAAGA
  TCCATGCAGGAGAGAAGGTGGGCATCGTGGGCAGAACAGGGGCCGGGAAGTCCTCCCTGGCTTGGGGCCT
  GCTGCGGCTTCAGGAGGCTGCCGAGGGTAATATCTGGATCGATGGGGTCCCTATCACCCATGTGGGGCTG
  CACACACTGAGGTCCCGAATCACCATCATCCCTCAGGACCCTGTCCTGTTCCCAGGCTCTCTGCGGATGA
  ACCTGGACCTGCTTCAGGAGCACACAGATGAAGGCATCTGGGCAGCGCTGGAGACAGTGCAGCTCAAGGC
  CTTCGTGACCAGCCTGCCTGGCCAGCTGCAATATGAGTGTGCAGGCCAGGGAGATGACCTGAGCGTGGGT
  CAGAAACAGCTCCTGTGCCTGGCACGAGCCCTTCTCCGGAAAACCCAGATCCTCATCCTGGACGAGGCGA
  CTGCCTCTGTGGACCCAGGGACGGAGATGCAGATGCAGGCGGCCCTGGAGCGCTGGTTTACACAGTGTAC
  CGTACTGCTTATCGCTCACCGCCTGCGCTCCGTGATGGACTGTGCCAGAGTCCTAGTCATGGATGAGGGG
  CAGGTGGCAGAAAGTGGCAGTCCTGCTCAGCTGCTGGCCCAGAAAGGCCTGTTTTACAGGCTAGCCCATG
  AGTCGGGCCTCGCT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR221951 representing NM_018795
  Red=Cloning site Green=Tags(s)
  
  MNRGRSMATPGEQCAGLRVWNQTEQEPAAYHLLSLCFVRAASSWVPPMYLWVLGPIYLLYIHRHGRCYLR
  MSHLFKTKMVLGLALILLYTFNVAVPLWRIHQGVPQAPELLIHPTVWLTTMSFATFLIHMERRKGVRSSG
  VLFGYWLLCCILPGINTVQQASAGNFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSQPLNPCP
  EAEASFPSKAMFWWASGLLWRGYKKLLGPKDLWSLGRENSSEELVSQLEREWRRSCNGLPGHKGHSSVGA
  PETEAFLQPERSQRGPLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDRNSSAWTGWLL
  AVLMFAAACLQTLFEQQHMYRAKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDIQRLAE
  SIIYLNGLWLLFLWIFVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRGFHQEEQMRQKASRARLTS
  SMLRTVRTIKSHGWEHAFLERLLHIRGQELSALKTSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNA
  MDAEKAFVTLTVLSILNKAQAFLPFSVHCIVQARVSFDRLAAFLCLEEVDPNGMIASNSRRSSKDRISVH
  NGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWV
  QNTSVVENVCFRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAA
  IYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQ
  RNGALVGLLDGARQPAGTHDAATSDDLGGFPGGGRPTCRPDRPRPTEAAPVKGRSTSEVQMEASLDDPEA
  TGLTAEEDSVRYGRVKTTIYLSYLRAVGTPLCTYTLFLFLCQQVASFSQGYWLSLWADDPVVDGRQMHAA
  LRGWVFGLLGCLQAIGLFASMAAVFLGGARASGLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDTV
  DVDIPDKLRSLLTYAFGLLEVGLAVTMATPLAIVAILPLMVLYAGFQSLYVATSCQLRRLESARYSSVCS
  HMAETFQGSLVVRAFRAQASFTAQHDALMDENQRVSFPKLVADRWLATNLELLGNGLVFVAATCAVLSKA
  HLSAGLVGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYARIPKEAPWRLPTCAAQPLWPCGGQI
  EFRDFGLRHRPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAWGLLRLQEAAEGNIWIDGVPITHVGL
  HTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAALETVQLKAFVTSLPGQLQYECAGQGDDLSVG
  QKQLLCLARALLRKTQILILDEATASVDPGTEMQMQAALERWFTQCTVLLIAHRLRSVMDCARVLVMDEG
  QVAESGSPAQLLAQKGLFYRLAHESGLA
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_018795
• ORF Size: 4494 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_018795.2, NP_061265.2
• RefSeq Size: 4958
• RefSeq ORF: 4497
• Locus ID: 27421
• MW: 165.3 kDa
• Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein is unknown; however, a similar rat protein has been identified as the major canalicular bile salt export pump of liver. [provided by RefSeq, Jul 2008]