Papss2 (NM_011864) Mouse Tagged ORF Clone

CAT#: MR225151L3

Lenti ORF clone of Papss2 (Myc-DDK-tagged) - Mouse 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2), transcript variant 1

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Papss2
• Synonyms: 1810018P12Rik; AI159688; Atpsk2; AtpsU2; bm; Sk2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR225151).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_011864
• ORF Size: 1866 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_011864.3, NP_035994.2
• RefSeq Size: 3635
• RefSeq ORF: 1866
• Locus ID: 23972
• Gene Summary: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have a important role in skeletogenesis during postnatal growth. [UniProtKB/Swiss-Prot Function]