Cldn17 (NM_181490) Mouse Tagged ORF Clone

CAT#: MR225211

Cldn17 (Myc-DDK-tagged) - Mouse claudin 17 (Cldn17)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Cldn17
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR225211 representing NM_181490
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTTTTTATCCCTTACAGATCGCTGGACTAGTTCTTGGATTCTTCGGTTTGGTTGGGACGATTGGGA
  CAACACTTCTGCCTCAATGGAGAGTGTCAGCTTTCATCGGCAGCAACATTATTATCTTTGAGAGGATCTG
  GGAAGGGCTTTGGATGAACTGCATCCAGCAAGCTATGGTCACCTTGCAGTGCAAATTCTATAACTCCATA
  TTGGCTCTCCCTCCGGTACTGGAAGCAGCGCGTGCCCTCATGTGTGTGGCTGTGGCTCTTGCCTTGGTTG
  CTCTCATTATTGGCATCTGCGGCATGAAACAGCTCCAGTGCACCGGCTCCAGCGAGAGGGTCAAAGCCTA
  CTTGCTTGGAACCTCAGGGGTGCTCTTTATTCTGACTGGTATCTTCGTTCTGATTCCAGTGTCCTGGACT
  GCTAATATCATCATCAGAGATTTCTACGACCCAACCGTTCATGCAGGGCAGAAGCGAGAACTTGGAGGAG
  CACTCTTCCTTGGCTGGGCAACCGCTGCTGTCCTCTTCATTGGAGGCGGGCTGCTCTGCGGATATTGCTG
  CTGCAACAGAAAGGAACGGTGGCACAGATACCCAGTCCCTGCATACCGCGTGCCACAGAAGGATAACCAA
  AGGAATGTTACTGTGCCTAGAAAATCTTCCACCAGCTACGTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR225211 representing NM_181490
  Red=Cloning site Green=Tags(s)
  
  MAFYPLQIAGLVLGFFGLVGTIGTTLLPQWRVSAFIGSNIIIFERIWEGLWMNCIQQAMVTLQCKFYNSI
  LALPPVLEAARALMCVAVALALVALIIGICGMKQLQCTGSSERVKAYLLGTSGVLFILTGIFVLIPVSWT
  ANIIIRDFYDPTVHAGQKRELGGALFLGWATAAVLFIGGGLLCGYCCCNRKERWHRYPVPAYRVPQKDNQ
  RNVTVPRKSSTSYV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_181490
• ORF Size: 672 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_181490.1, NM_181490.2, NM_181490.3, NP_852467.1
• RefSeq Size: 1172
• RefSeq ORF: 675
• Locus ID: 239931
• MW: 25.1 kDa
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with the Cldn8 gene on chromosome 16. [provided by RefSeq, Aug 2010]