Cldn1 (NM_016674) Mouse Tagged ORF Clone
CAT#: MR225404
- TrueORF®
Cldn1 (Myc-DDK-tagged) - Mouse claudin 1 (Cldn1)
"NM_016674" in other vectors (3)
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Cldn1 |
Synonyms | AI596271 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR225404 representing NM_016674
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCAACGCGGGGCTGCAGCTGCTGGGTTTCATCCTGGCTTCTCTGGGATGGATCGGCTCCATCGTCA GCACTGCCCTGCCCCAGTGGAAGATTTACTCCTATGCTGGGGACAACATCGTGACCGCTCAGGCCATCTA CGAGGGACTGTGGATGTCCTGCGTTTCGCAAAGCACCGGGCAGATACAGTGCAAAGTCTTCGATTCCTTG CTGAATCTGAACAGTACTTTGCAGGCAACCCGAGCCTTGATGGTAATTGGCATCCTGCTGGGGCTGATCG CAATCTTTGTGTCCACCATTGGCATGAAGTGCATGAGGTGCCTGGAAGATGATGAGGTGCAGAAGATGTG GATGGCTGTCATTGGGGGCATAATATTTTTAATTTCAGGTCTGGCGACATTAGTGGCCACAGCATGGTAT GGAAACAGAATTGTTCAAGAATTCTATGACCCCTTGACCCCCATCAATGCCAGGTATGAATTTGGCCAGG CCCTCTTTACTGGCTGGGCCGCTGCCTCCCTCTGCCTTCTGGGAGGTGTCCTACTTTCCTGCTCCTGTCC CCGGAAAACAACCTCTTACCCAACACCACGGCCTTATCCCAAGCCAACACCTTCTAGTGGGAAAGACTAT GTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR225404 representing NM_016674
Red=Cloning site Green=Tags(s) MANAGLQLLGFILASLGWIGSIVSTALPQWKIYSYAGDNIVTAQAIYEGLWMSCVSQSTGQIQCKVFDSL LNLNSTLQATRALMVIGILLGLIAIFVSTIGMKCMRCLEDDEVQKMWMAVIGGIIFLISGLATLVATAWY GNRIVQEFYDPLTPINARYEFGQALFTGWAAASLCLLGGVLLSCSCPRKTTSYPTPRPYPKPTPSSGKDY V TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_016674 |
ORF Size | 633 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_016674.1, NM_016674.2, NM_016674.3, NM_016674.4, NP_057883.1 |
RefSeq Size | 3263 |
RefSeq ORF | 636 |
Locus ID | 12737 |
MW | 23.3 kDa |
Gene Summary | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The knockout mice lacking this gene die soon after birth as a consequence of dehydration from trandermal water loss, indicating that this gene is indispensable for creating and maintaining the epidermal barrier. The protein encoded by this gene also has gastric tumor suppressive activity, and is a key factor for hepatitis C virus (HCV) entry. [provided by RefSeq, Aug 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG225404 | Cldn1 (GFP-tagged) - Mouse claudin 1 (Cldn1), (10ug) |
USD 460.00 |
|
MR225404L3 | Lenti ORF clone of Cldn1 (Myc-DDK-tagged) - Mouse claudin 1 (Cldn1) |
USD 620.00 |
|
MR225404L4 | Lenti ORF clone of Cldn1 (mGFP-tagged) - Mouse claudin 1 (Cldn1) |
USD 620.00 |
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