Gdf6 (NM_013526) Mouse Tagged ORF Clone

CAT#: MR226291

Gdf6 (Myc-DDK-tagged) - Mouse growth differentiation factor 6 (Gdf6)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Gdf6
• Synonyms: BMP-13; BMP13; GDF16
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR226291 representing NM_013526
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACACTCCTAGGGTCCTTCTCTGGGCGATCTTCCTCATTAGCTTCCTCTGGGATTTGCCGGGTTTCC
  AGCAGGCTTCCATCTCCTCGTCCTCCTCCTCCTCCACCGAATTGGACTCCACCAAAGACGTGGGGAACCG
  CAAAGAAGGGAAGATGCAGCGAACTCCACAAGAGAGTGCCGAGGGCCGGACGCCCCCGGAGCACGGGCTG
  CGGCAGAAGGACCTCCGGCGGCGGCCGCCCGGACAACATCAGGGGCAGGAGCCGCCGGGCAGGGGGCTGC
  GCGTGGTGCCTCACGAGTACATGCTGTCAATCTACAAGACTTACTCCATTGCCGAGAAGCTGGGCATCAA
  TGCCAGCTTTTTCCAGTCTTCCAAGTCAGCTAATACGATCACTAGCTTTGTAGACAGAGGACTGGACGAT
  CTCTCGCACACTCCTCTCCGGAGACAGAAGTATTTGTTTGATGTGTCCACACTCTCAGACAAAGAAGAGC
  TGGTGGGCGCAGAGCTAAGGCTTTATCGCCAGGCGCCCCCAACGCCCTGGGGGCTACCGGCCCGACCGCT
  GCACTTGCAGCTCTTCCCTTGTTTATCCCCATTGCTACTGGACGCCAGGACCCTGGATCCTCAGGGACCA
  ACCCAGGCCGGCTGGGAAGTCTTCGACGTGTGGCAGGGCCTGCGCCCTCAGCCTTGGAAGCAGCTGTGCC
  TGGAGTTGCGGGCAGCCTGGGGTGAGCTGGACGCCGGGGATACGGGGGCGCGCGCGAGGGGTCCCCAGCA
  GCCACCGCCTCTGGACCTGCGGAGTCTGGGCTTCGGTCGGAGGGTGAGGCCGCCCCAGGAGCGCGCCCTG
  CTTGTAGTGTTCACCAGATCGCAGCGCAAGAACCTGTTCACTGAGATGCATGAGCAGCTGGGCTCTGCAG
  AGGCTGCGGGAGCCGAGGGGTCATGGCCAGCGCCGTCGGGCTCCCCAGACGCCGGGTCTTGGCTGCCCTC
  GCCCGGCCGCCGGCGGCGACGCACCGCCTTCGCCAGCCGTCACGGCAAGCGACATGGCAAGAAGTCCAGG
  CTGCGCTGCAGCAGAAAGCCTCTGCACGTGAATTTTAAGGAGTTAGGCTGGGACGACTGGATTATCGCGC
  CCCTAGAGTACGAGGCCTATCACTGCGAGGGCGTGTGCGACTTTCCGCTGCGCTCGCACCTTGAGCCCAC
  TAACCATGCCATCATTCAGACGCTGATGAACTCCATGGACCCGGGCTCCACCCCGCCTAGCTGCTGCGTT
  CCCACCAAACTGACTCCCATTAGCATCCTGTACATCGACGCGGGCAATAATGTAGTCTACAAGCAGTATG
  AGGACATGGTGGTGGAGTCCTGCGGCTGTAGG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR226291 representing NM_013526
  Red=Cloning site Green=Tags(s)
  
  MDTPRVLLWAIFLISFLWDLPGFQQASISSSSSSSTELDSTKDVGNRKEGKMQRTPQESAEGRTPPEHGL
  RQKDLRRRPPGQHQGQEPPGRGLRVVPHEYMLSIYKTYSIAEKLGINASFFQSSKSANTITSFVDRGLDD
  LSHTPLRRQKYLFDVSTLSDKEELVGAELRLYRQAPPTPWGLPARPLHLQLFPCLSPLLLDARTLDPQGP
  TQAGWEVFDVWQGLRPQPWKQLCLELRAAWGELDAGDTGARARGPQQPPPLDLRSLGFGRRVRPPQERAL
  LVVFTRSQRKNLFTEMHEQLGSAEAAGAEGSWPAPSGSPDAGSWLPSPGRRRRRTAFASRHGKRHGKKSR
  LRCSRKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPGSTPPSCCV
  PTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_013526
• ORF Size: 1362 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013526.1, NP_038554.1
• RefSeq Size: 3532
• RefSeq ORF: 1365
• Locus ID: 242316
• MW: 51.4 kDa
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mice lacking a functional copy of this gene exhibit joint and skeletal defects. [provided by RefSeq, Sep 2016]