Meis2 (NM_001159570) Mouse Tagged ORF Clone

CAT#: MR226573

Meis2 (Myc-DDK-tagged) - Mouse Meis homeobox 2 (Meis2), transcript variant 6

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Meis2
• Synonyms: A430109D20Rik; Mrg1; Stra10
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR226573 representing NM_001159570
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTTCTGTACGATGAGCTGCCCCATTACGGCGGGATGGACGGAGTAGGGGTTCCCGCTTCCATGTACG
  GAGACCCTCACGCGCCGCGGCCGATCCCCCCGGTTCACCACCTAAACCACGGGCCGCCGCTCCACGCCAC
  GCAGCACTACGGCGCGCACGCCCCGCACCCCAATGTCATGCCAGCCAGCATGGGATCTGCTGTCAACGAC
  GCCTTGAAAAGAGACAAGGACGCAATCTATGGGCACCCGTTGTTTCCTCTGTTAGCTCTGGTTTTTGAGA
  AGTGCGAGCTGGCGACCTGCACTCCCCGGGAACCCGGAGTGGCCGGCGGAGACGTCTGTTCCTCTGACTC
  CTTCAACGAGGACATCGCGGTCTTCGCCAAGCAGGTTCGCGCCGAAAAGCCTCTTTTTTCCTCAAACCCA
  GAGCTGGATAATTTGATGATACAAGCAATTCAAGTACTAAGGTTTCATCTTCTGGAGTTAGAAAAGGTCC
  ACGAACTATGTGATAACTTCTGCCACCGGTACATTAGCTGTTTGAAGGGAAAAATGCCCATTGACCTCGT
  GATTGATGAGAGAGATGGAAGCTCCAAGTCAGATCATGAAGAACTTTCAGGCTCCTCCACAAATCTCGCC
  GACCACAACCCTTCATCCTGGCGAGACCACGATGACGCAACCTCAACGCACTCCGCAGGCACCCCAGGAC
  CCTCCAGTGGGGGCCATGCTTCCCAGAGTGGAGACAACAGCAGTGAGCAAGGCGATGGGTTAGACAACAG
  CGTAGCTTCACCTGGCACAGGTGATGACGACGATCCAGACAAGGACAAAAAACGCCAGAAGAAAAGAGGC
  ATATTCCCCAAAGTCGCGACAAATATCATGAGAGCGTGGCTCTTCCAGCATCTCACACACCCGTACCCTT
  CAGAAGAACAGAAGAAACAGTTAGCGCAAGACACGGGACTGACAATTCTGCAAGTGAACAACTGGTTTAT
  CAATGCCAGAAGAAGAATAGTGCAGCCCATGATTGACCAGTCAAATCGAGCAGTGAGCCAAGGAGCAGCG
  TATAGTCCAGAGGGTCAGCCCATGGGGAGCTTTGTGTTGGATGGTCAGCAACACATGGGGATCCGGCCTG
  CAGGACCCATGAGTGGAATGGGCATGAATATGGGCATGGATGGGCAGTGGCACTATATG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR226573 representing NM_001159570
  Red=Cloning site Green=Tags(s)
  
  MFLYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVND
  ALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNP
  ELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLA
  DHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRG
  IFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
  YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001159570
• ORF Size: 1179 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001159570.1, NM_001159570.2, NP_001153042.1
• RefSeq Size: 4989
• RefSeq ORF: 1182
• Locus ID: 17536
• MW: 43.4 kDa
• Gene Summary: This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcriptional regulators and several members have been shown to be essential contributors to developmental programs. In mice, a knock-out of this gene leads to lethality at embryonic day 14, accompanied with hemorrhaging. Embryos lacking this gene show defects in tissues derived from the neural crest, suggesting a critical role of this gene during cranial and cardiac neural crest cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]