Htr2c (NM_008312) Mouse Tagged ORF Clone
CAT#: MR226671L4
- LentiORF®
Lenti ORF clone of Htr2c (mGFP-tagged) - Mouse 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c)
"NM_008312" in other vectors (4)
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Product Images
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Htr2c |
Synonyms | 5-HT2C; 5-HT2cR; 5-HTR2C; 5HT1c; Htr1c; SR1 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226671).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_008312 |
ORF Size | 1377 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008312.4, NP_032338.3 |
RefSeq Size | 4765 |
RefSeq ORF | 1380 |
Locus ID | 15560 |
Gene Summary | Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in rodents show altered patterns of RNA editing in response to drug treatments and stressful situations. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC216115 | Htr2c (untagged) - Mouse 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c), (10ug) |
USD 630.00 |
|
MR226671 | Htr2c (Myc-DDK-tagged) - Mouse 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c) |
USD 480.00 |
|
MG226671 | Htr2c (GFP-tagged) - Mouse 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c), (10ug) |
USD 530.00 |
|
MR226671L3 | Lenti ORF clone of Htr2c (Myc-DDK-tagged) - Mouse 5-hydroxytryptamine (serotonin) receptor 2C (Htr2c) |
USD 680.00 |
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