Cln3 (NM_009907) Mouse Tagged ORF Clone

CAT#: MR227238

Cln3 (Myc-DDK-tagged) - Mouse ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) (Cln3), transcript variant 2

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Cln3
• Synonyms: AI323623
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR227238 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGAAGTTCTGCGGGCTCGTGGAGGCGCCTTGAGGATTCTGAGAGGGAGGAGACCGACTCAGAGCCCC
  AGGCCCCTCGGTTGGATAGTCGGAGTGTCCTTTGGAAGAATGCAGTGGGTTTCTGGATCTTGGGTCTTTG
  CAACAATTTCTCATATGTGGTGATGCTGAGCGCTGCCCATGACATCCTCAAGCAGGAGCAGGCGTCTGGA
  AACCAGAGCCATGTAGAACCAGGCCCAACACCCACACCCCACAACAGCTCATCTCGATTTGACTGCAACT
  CCATCTCCACAGCTGCGGTGCTCCTAGCAGACATCCTTCCCACCCTTGTCATCAAACTCCTGGCGCCTCT
  TGGCCTTCACTTGCTGCCTTACAGCCCCCGGGTGCTCGTCAGTGGAGTTTGTTCTGCTGGGAGCTTTGTT
  CTGGTTGCCTTCTCTCAGTCAGTGGGGTTAAGCCTGTGTGGAGTGGTTTTGGCCAGCATCTCCTCAGGGC
  TAGGGGAGGTCACCTTCCTCTCACTGACTGCCTTCTACCCCAGTGCTGTGATCTCATGGTGGTCTTCGGG
  TACCGGGGGTGCAGGGCTTCTTGGATCGCTGTCTTACCTGGGACTCACCCAGGCTGGCCTCTCCCCGCAG
  CACACCCTACTTTCTATGTTGGGGATCCCTGTTCTGCTGCTAGCCAGCTATTTCTTGTTGCTCACGTCTC
  CTGAACCCCTGGACCCTGGAGGGGAAAACGAGGCAGAGACTGCTGCCCGGCAGCCTCTCATAGGCACCGA
  GACCCCAGAGTCAAAGCCAGGTGCCAGCTGGGACCTCTCCCTCCAGGAAAGGTGGACAGTGTTCAAGGGT
  CTCTTGTGGTACATCATCCCTCTGGTGCTGGTCTACTTTGCAGAATACTTTATCAACCAGGGACTTTTCG
  AGCTCCTGTTTTTCCGGAACACTTCCCTAAGCCATGCTCAGCAGTACCGATGGTACCAGATGCTATACCA
  GGCTGGTGTGTTCGCCTCCCGCTCTTCTCTCCAATGTTGCCGAATACGGTTCACCTGGGTCCTAGCCCTG
  CTCCAGTGCCTCAACCTGGCCCTCCTGCTGGCAGATGTCTGCTTGAACTTCTTGCCCAGCATCTACCTCA
  TCTTCATCATCATTCTGTACGAAGGGCTCCTGGGTGGGGCCGCTTACGTGAATACCTTCCACAACATTGC
  TCTGGAGACCAGTGACAAGCACCGAGAGTTTGCCATGGAAGCTGCCTGTATCTCTGACACCTTGGGAATC
  TCCCTGTCGGGGGTCCTGGCCCTGCCTCTGCATGACTTCCTCTGTCACCTCCCT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR227238 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MGSSAGSWRRLEDSEREETDSEPQAPRLDSRSVLWKNAVGFWILGLCNNFSYVVMLSAAHDILKQEQASG
  NQSHVEPGPTPTPHNSSSRFDCNSISTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGVCSAGSFV
  LVAFSQSVGLSLCGVVLASISSGLGEVTFLSLTAFYPSAVISWWSSGTGGAGLLGSLSYLGLTQAGLSPQ
  HTLLSMLGIPVLLLASYFLLLTSPEPLDPGGENEAETAARQPLIGTETPESKPGASWDLSLQERWTVFKG
  LLWYIIPLVLVYFAEYFINQGLFELLFFRNTSLSHAQQYRWYQMLYQAGVFASRSSLQCCRIRFTWVLAL
  LQCLNLALLLADVCLNFLPSIYLIFIIILYEGLLGGAAYVNTFHNIALETSDKHREFAMEAACISDTLGI
  SLSGVLALPLHDFLCHLP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_009907
• ORF Size: 1317 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_009907.1, NM_009907.2, NM_009907.3, NM_009907.4, NP_034037.3
• RefSeq Size: 2375
• RefSeq ORF: 1317
• Locus ID: 12752
• MW: 47.7 kDa
• Gene Summary: This gene encodes a transmembrane protein called battenin that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis genes, cause a number of neurodegenerative diseases collectively known as neuronal ceroid lipofuscinoses, the most common of which is juvenile neuronal ceroid-lipofuscinosis (Batten disease). Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]