Cdh3 (NM_007665) Mouse Tagged ORF Clone

CAT#: MR227345

Cdh3 (Myc-DDK-tagged) - Mouse cadherin 3 (Cdh3), transcript variant 2

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Cdh3
• Synonyms: AI385538; Cadp; Cdhp; P-cadherin; Pcad
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR227345 representing NM_007665
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCTTCTTAGTGGGCCTCACGCCTTCCTGCTCCTCCTGCTCCAGGTTTGCTGGCTACGCAGCGTGG
  TCTCCGAGCCCTACCGAGCGGGCTTCATCGGGGAGGCTGGAGTGACCTTGGAGGTGGAAGGAACTGACCT
  GGAGCCGAGCCAAGTTCTGGGGAAAGCCTTGGCTGGACAGGGCATGCACCATGCAGACAATGGAGACATC
  ATTATGCTGACTAGGGGGACAGTTCAGGGAGGGAAGGATGCGATGCACTCCCCACCCACCCGCATCTTAA
  GGAGACGAAAGAGAGAGTGGGTGATGCCACCAATATTCGTCCCCGAGAATGGCAAGGGTCCCTTCCCTCA
  GAGGCTGAATCAGCTCAAATCTAATAAGGACAGAGGCACCAAGATTTTCTACAGCATCACAGGGCCTGGC
  GCAGACAGTCCCCCCGAAGGAGTCTTCACCATAGAGAAGGAGTCGGGCTGGCTGTTGTTGCATATGCCAC
  TGGACAGGGAGAAGATTGTCAAGTACGAGCTTTATGGCCACGCTGTATCTGAGAATGGTGCCTCTGTAGA
  GGAGCCCATGAACATATCCATCATTGTGACAGACCAGAATGACAACAAGCCCAAGTTCACTCAAGACACC
  TTCAGAGGGAGTGTTCTGGAGGGAGTAATGCCTGGCACTTCTGTGATGCAGGTGACAGCCACAGATGAGG
  ACGATGCTGTCAACACTTACAATGGGGTGGTGGCTTACTCCATCCATAGCCAAGAGCCGAAGGAGCCACA
  CGACCTCATGTTCACCATCCATAAAAGCACGGGAACCATTAGCGTCATATCCAGTGGCCTGGACCGAGAG
  AAAGTCCCTGAGTACAGACTGACCGTCCAGGCCACAGACATGGATGGAGAGGGCTCTACCACGACGGCAG
  AGGCCGTTGTGCAAATCCTTGATGCCAACGATAACGCTCCGGAGTTTGAGCCGCAGAAGTATGAGGCTTG
  GGTGCCTGAGAACGAAGTGGGCCATGAGGTACAGAGGCTGACAGTGACTGATCTCGATGTCCCCAACTCG
  CCAGCGTGGCGTGCCACCTACCACATCGTGGGAGGTGATGATGGGGACCATTTCACCATCACCACTCACC
  CAGAGACCAACCAAGGCGTCCTGACAACCAAGAAGGGTTTGGATTTTGAGGCTCAGGACCAACACACCCT
  GTATGTAGAAGTGACCAACGAGGCTCCCTTTGCAGTGAAGCTCCCGACAGCCACTGCCACCGTGGTGGTC
  CATGTGAAAGATGTCAACGAAGCCCCTGTGTTTGTTCCACCTTCCAAGGTCATTGAGGCCCAGGAAGGCA
  TCTCTATTGGGGAACTGGTCTGCATCTATACCGCACAGGACCCAGACAAGGAGGACCAGAAGATCAGCTA
  CACCATCTCGAGAGATCCAGCCAACTGGCTTGCTGTGGACCCAGACAGTGGTCAGATAACTGCCGCAGGC
  ATCTTGGATCGTGAGGACGAGCAGTTTGTGAAAAACAATGTCTACGAAGTCATGGTTTTGGCCACAGACA
  GTGGAAACCCTCCCACCACCGGCACTGGGACCCTCCTGCTTACACTTACTGACATCAACGACCATGGCCC
  GATCCCTGAACCCAGGCAGATCATCATCTGTAACCAAAGCCCTGTGCCTCAAGTGCTGAACATCACTGAC
  AAGGACCTGTCCCCCAACTCCTCCCCTTTCCAGGCCCAGCTAACACATGACTCAGATATCTACTGGATGG
  CAGAAGTCAGCGAGAAAGGAGACACCGTGGCCTTGTCCCTGAAGAAGTTCCTGAAACAAGACACGTATGA
  CTTGCATCTTTCTTTGTCTGACCATGGCAACAGGGAACAGCTAACCATGATCAGGGCCACTGTGTGTGAC
  TGCCATGGCCAAGTGTTCAATGACTGCCCCAGACCCTGGAAGGGTGGTTTCATCCTCCCCATCCTGGGTG
  CTGTCCTGGCACTGCTGACCCTTCTACTGGCACTCCTCCTGTTGGTGAGGAAGAAGAGGAAGGTCAAAGA
  GCCCCTTCTGCTCCCAGAAGATGACACGCGAGACAATGTCTTCTATTATGGAGAAGAGGGTGGTGGTGAA
  GAGGACCAGGACTATGACATCACCCAACTCCACCGGGGACTGGAGGCCAGGCCTGAGGTGGTTCTCCGAA
  ACGATGTAGTGCCAACCTTCATCCCCACCCCCATGTACCGACCCCGGCCCGCCAACCCAGATGAAATCGG
  GAACTTCATCATCGAGAACCTGAAGGCTGCCAACACTGACCCTACTGCCCCGCCCTACGACTCCCTGCTG
  GTTTTTGACTACGAGGGCAGCGGCTCTGATGCCGCCTCCCTGAGCTCCCTCACCACCTCCGCCTCCGACC
  AGGATCAGGACTACAACTACCTTAACGAGTGGGGAAGTCGATTCAAGAAACTGGCGGACATGTATGGTGG
  CGGTGAGGATGAC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR227345 representing NM_007665
  Red=Cloning site Green=Tags(s)
  
  MELLSGPHAFLLLLLQVCWLRSVVSEPYRAGFIGEAGVTLEVEGTDLEPSQVLGKALAGQGMHHADNGDI
  IMLTRGTVQGGKDAMHSPPTRILRRRKREWVMPPIFVPENGKGPFPQRLNQLKSNKDRGTKIFYSITGPG
  ADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDT
  FRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDRE
  KVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEFEPQKYEAWVPENEVGHEVQRLTVTDLDVPNS
  PAWRATYHIVGGDDGDHFTITTHPETNQGVLTTKKGLDFEAQDQHTLYVEVTNEAPFAVKLPTATATVVV
  HVKDVNEAPVFVPPSKVIEAQEGISIGELVCIYTAQDPDKEDQKISYTISRDPANWLAVDPDSGQITAAG
  ILDREDEQFVKNNVYEVMVLATDSGNPPTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITD
  KDLSPNSSPFQAQLTHDSDIYWMAEVSEKGDTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCD
  CHGQVFNDCPRPWKGGFILPILGAVLALLTLLLALLLLVRKKRKVKEPLLLPEDDTRDNVFYYGEEGGGE
  EDQDYDITQLHRGLEARPEVVLRNDVVPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLL
  VFDYEGSGSDAASLSSLTTSASDQDQDYNYLNEWGSRFKKLADMYGGGEDD
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_007665
• ORF Size: 2463 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007665.1, NM_007665.2, NM_007665.3, NP_031691.1
• RefSeq Size: 4034
• RefSeq ORF: 2466
• Locus ID: 12560
• MW: 91 kDa
• Gene Summary: This gene encodes a calcium-dependent cell-cell adhesion protein containing five cadherin domains. The encoded protein plays a role in epithelial outgrowth, such as that which occurs during the development of hair follicles and limb buds. Loss of function of the related gene in humans results in ectodermal dysplasia, ectrodactyly, and macular dystrophy and congential hypotrichosis with juvenile macular dystrophy. This gene is located in the vicinity of similar cadherin genes on chromosome 8. The proprotein is further cleaved into a functional chain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]