Fgf23 (NM_022657) Mouse Tagged ORF Clone

CAT#: MR227482

Fgf23 (Myc-DDK-tagged) - Mouse fibroblast growth factor 23 (Fgf23)

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Fgf23
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR227482 ORF sequence
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTAGGGACCTGCCTTAGACTCCTGGTGGGCGCGCTCTGCACTGTCTGCAGCTTGGGCACTGCTAGAG
  CCTATCCAGACACTTCCCCATTGCTTGGCTCCAACTGGGGAAGCCTGACCCACCTGTACACGGCTACAGC
  CAGGACCAGCTATCACCTACAGATCCATAGGGATGGTCATGTAGATGGCACCCCCCATCAGACCATCTAC
  AGTGCCCTGATGATTACATCAGAGGACGCCGGCTCTGTGGTGATAACAGGAGCCATGACTCGAAGGTTCC
  TTTGTATGGATCTCCACGGCAACATTTTTGGATCGCTTCACTTCAGCCCAGAGAATTGCAAGTTCCGCCA
  GTGGACGCTGGAGAATGGCTATGACGTCTACTTGTCGCAGAAGCATCACTACCTGGTGAGCCTGGGCCGC
  GCCAAGCGCATCTTCCAGCCGGGCACCAACCCGCCGCCCTTCTCCCAGTTCCTGGCGCGCAGGAACGAGG
  TCCCGCTGCTGCACTTCTACACTGTTCGCCCACGGCGCCACACGCGCAGCGCCGAGGACCCACCCGAGCG
  CGACCCACTGAACGTGCTCAAGCCGCGGCCCCGCGCCACGCCTGTGCCTGTATCCTGCTCTCGCGAGCTG
  CCGAGCGCAGAGGAAGGTGGCCCCGCAGCCAGCGATCCTCTGGGGGTGCTGCGCAGAGGCCGTGGAGATG
  CTCGCGGGGGCGCGGGAGGCGCGGATAGGTGTCGCCCCTTTCCCAGGTTCGTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR227482 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MLGTCLRLLVGALCTVCSLGTARAYPDTSPLLGSNWGSLTHLYTATARTSYHLQIHRDGHVDGTPHQTIY
  SALMITSEDAGSVVITGAMTRRFLCMDLHGNIFGSLHFSPENCKFRQWTLENGYDVYLSQKHHYLVSLGR
  AKRIFQPGTNPPPFSQFLARRNEVPLLHFYTVRPRRHTRSAEDPPERDPLNVLKPRPRATPVPVSCSREL
  PSAEEGGPAASDPLGVLRRGRGDARGGAGGADRCRPFPRFV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_022657
• ORF Size: 756 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_022657.1, NM_022657.2, NM_022657.3, NM_022657.4, NP_073148.1
• RefSeq Size: 2702
• RefSeq ORF: 756
• Locus ID: 64654
• MW: 27.7 kDa
• Gene Summary: This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic rickets (ADHR). The secreted protein is further cleaved into N- and C-terminal chains, which results in loss of function. [provided by RefSeq, Mar 2013]