Cdkn1c (NM_001161624) Mouse Tagged ORF Clone

CAT#: MR227583

Cdkn1c (Myc-DDK-tagged) - Mouse cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c), transcript variant 1

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Cdkn1c
• Synonyms: AL024410; CDKI; Kip2; p57(kip2); p57Kip2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR227583 representing NM_001161624
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCATGTCCGACGTGTACCTCCGCAGCAGAACAGCGATGGAACGCTTGGCCTCCAGCGATACCTTCC
  CAGTGATAGCGCGTAGCAGCGCCTGCCGCAGCCTCTTCGGGCCTGTAGACCACGAGGAGCTGGGCCGCGA
  GCTGCGGATGCGCCTGGCCGAGCTGAACGCCGAGGACCAGAACCGCTGGGACTTCAACTTCCAGCAGGAT
  GTGCCTCTTCGAGGCCCTGGTCGTCTGCAGTGGATGGAGGTGGACAGCGAGTCTGTGCCCGCCTTCTACC
  GCGAGACGGTGCAGGTGGGGCGCTGTCGCCTGCAGCTGGGGCCCCGGCCACCCCCGGTGGCCGTGGCTGT
  CATCCCGCGTTCTGGGCCGCCGGCTGGCGAGGCCCCCGACGGCCTAGAGGAGGCGCCTGAGCAGCCGCCC
  AGCGCCCCAGCCTCGGCCGTGGTCGCGGAGCCCACCCCACCCGCGACCCCGGCCCCGGCTTCAGATCTGA
  CCTCAGACCCAATTCCGGAGGTGACCCTGGTCGCGACCTCCGACCCGACTCCGGACCCGATCCCGGACGC
  GAACCCGGACGTGGCGACTCGGGACGGCGAGGAACAGGTCCCTGAGCAGGTCTCTGAGCAGGGCGAGGAG
  TCGGGTGCTGAGCCGGGTGATGAGCTGGGAACTGAGCCGGTCTCTGAGCAGGGCGAGGAGCAGGGCGCAG
  AGCCGGTCGAGGAGAAGGACGAGGAGCCGGAGGAGGAGCAGGGCGCGGAGCCGGTCGAGGAGCAGGGTGC
  GGAGCCGGTCGAGGAGCAGAATGGGGAGCCGGTCGAGGAGCAGGACGAGAATCAAGAGCAGCGCGGCCAG
  GAGCTGAAGGACCAGCCTCTCTCGGGGATTCCAGGACGTCCTGCACCCGGGACTGCTGCGGCCAATGCGA
  ACGACTTCTTCGCCAAGCGCAAGAGAACTGCGCAGGAGAACAAGGCGTCGAACGACGTCCCTCCAGGGTG
  TCCCTCTCCAAACGTGGCTCCTGGGGTGGGCGCGGTGGAGCAGACCCCGCGCAAACGTCTGAGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR227583 representing NM_001161624
  Red=Cloning site Green=Tags(s)
  
  MGMSDVYLRSRTAMERLASSDTFPVIARSSACRSLFGPVDHEELGRELRMRLAELNAEDQNRWDFNFQQD
  VPLRGPGRLQWMEVDSESVPAFYRETVQVGRCRLQLGPRPPPVAVAVIPRSGPPAGEAPDGLEEAPEQPP
  SAPASAVVAEPTPPATPAPASDLTSDPIPEVTLVATSDPTPDPIPDANPDVATRDGEEQVPEQVSEQGEE
  SGAEPGDELGTEPVSEQGEEQGAEPVEEKDEEPEEEQGAEPVEEQGAEPVEEQNGEPVEEQDENQEQRGQ
  ELKDQPLSGIPGRPAPGTAAANANDFFAKRKRTAQENKASNDVPPGCPSPNVAPGVGAVEQTPRKRLR
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001161624
• ORF Size: 1044 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001161624.1, NP_001155096.1
• RefSeq Size: 1952
• RefSeq ORF: 1047
• Locus ID: 12577
• MW: 37.4 kDa
• Gene Summary: Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. [UniProtKB/Swiss-Prot Function]