Lmna (NM_001111102) Mouse Tagged ORF Clone
CAT#: MR227597
- TrueORF®
Lmna (Myc-DDK-tagged) - Mouse lamin A (Lmna), transcript variant 3
"NM_001111102" in other vectors (3)
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Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Lmna |
Synonyms | Dhe |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR227597 representing NM_001111102
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGACCCCGTCACAGCGGCGCGCCACCCGCAGTGGGGCGCAGGCCAGCTCTACCCCACTGTCGCCCA CTCGGATCACCCGGCTGCAGGAGAAGGAGGACCTGCAGGAGCTCAATGACCGCCTGGCCGTGTACATCGA TCGCGTGCGTTCCCTGGAGACCGAGAACGCGGGGCTGCGCCTTCGCATCACTGAGTCTGAAGAGGTGGTC AGCCGAGAGGTGTCCGGCATCAAGGCGGCCTACGAGGCCGAGCTGGGGGATGCCCGCAAGACCCTTGATT CTGTGGCCAAGGAGCGCGCCCGCCTCCAGCTAGAGCTGAGCAAAGTGCGTGAGGAGTTCAAGGAGCTGAA GGCTCGCAACACCAAGAAGGAGGGGGACTTGTTGGCTGCGCAGGCCCGGCTCAAGGACCTCGAGGCTCTT CTCAACTCCAAGGAAGCTGCCCTGAGCACTGCTCTCAGTGAGAAGCGCACATTGGAGGGCGAGCTCCATG ACCTGCGGGGGCAGGTAGCCAAGCTTGAGGCGGCCCTGGGAGAGGCTAAGAAGCAGCTTCAGGATGAGAT GCTGAGGCGAGTGGATGCTGAGAACAGGCTACAGACGCTGAAGGAGGAGCTTGACTTCCAGAAGAACATT TACAGCGAGGAACTGCGTGAGACCAAGCGCCGGCATGAGACGCGGCTTGTGGAGATCGATAACGGGAAGC AGCGAGAGTTTGAGAGCCGGCTGGCAGATGCCCTGCAGGAGCTGCGGGCTCAGCATGAGGACCAGGTGGA ACAGTATAAGAAGGAGCTAGAAAAGACATACTCCGCCAAGCTGGATAATGCCAGGCAGTCTGCTGAGAGG AACAGCAACCTCGTGGGGGCTGCCCATGAGGAACTGCAGCAGTCTCGAATCCGCATTGACAGCCTCTCGG CCCAGCTCAGCCAGCTCCAAAAGCAGTTGGCAGCCAAGGAGGCAAAGCTGCGTGACCTGGAGGACTCGCT GGCCCGTGAGCGCGATACCAGCCGGCGCCTGCTGGCTGAGAAAGAGCGAGAGATGGCGGAGATGCGGGCG AGGATGCAGCAGCAGCTGGACGAGTACCAGGAGCTGCTGGACATCAAGCTGGCCCTGGACATGGAGATCC ATGCCTATCGAAAGCTGCTGGAGGGCGAGGAGGAGAGGCTGCGCCTGTCCCCCAGCCCTACCTCGCAGCG CAGCCGTGGCCGCGCCTCCTCCCACTCATCCCAGTCTCAGGGTGGAGGCAGCGTCACCAAAAAGCGCAAG CTGGAGTCTTCCGAGAGCCGGAGCAGCTTCTCGCAGCATGCTCGCACTAGCGGGCGTGTGGCGGTAGAGG AAGTCGATGAAGAGGGAAAGTTCGTGCGGCTGCGCAACAAGTCCAACGAGGACCAGTCCATGGGCAACTG GCAGATCAGGCGTCAGAATGGTGACGATCCTTTGATGACCTATCGCTTCCCACCGAAGTTCACCCTAAAG GCTGGGCAGGTGGTGACGATCTGGGCTTCAGGAGCTGGGGCCACCCATAGCCCCCCTACTGACTTGGTGT GGAAGGCGCAGAACACCTGGGGCTGTGGGAGCAGCCTTCGCACCGCTCTCATCAACTCCACTGGAGAAGA AGTGGCCATGCGCAAGCTGGTGCGCTCACTGACCATGGTTGAGGACAATGAGGATGACGACGAGGATGGA GAAGAGCTCCTCCATCACCACCGTGTGAGTGGCAGCCGCCGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR227597 representing NM_001111102
Red=Cloning site Green=Tags(s) METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVV SREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEAL LNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNI YSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAER NSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRA RMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRK LESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLK AGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLTMVEDNEDDDEDG EELLHHHRVSGSRR TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001111102 |
ORF Size | 1722 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001111102.1, NM_001111102.2, NP_001104572.1 |
RefSeq Size | 2045 |
RefSeq ORF | 1725 |
Locus ID | 16905 |
MW | 65.9 kDa |
Gene Summary | This gene encodes a protein that is a member of the lamin family. Nuclear lamins, intermediate filament-like proteins, are the major components of the nuclear lamina, a protein meshwork associated with the inner nuclear membrane. This meshwork is thought to maintain the integrity of the nuclear envelope, participate in chromatin organization, and regulate gene transcription. Vertebrate lamins consist of two types, A and B. This protein is an A-type and is proposed to be developmentally regulated. In mouse deficiency of this gene is associated with muscular dystrophy. Mouse lines with different mutations in this gene serve as pathophysiological models for several human laminopathies. In humans, mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG227597 | Lmna (GFP-tagged) - Mouse lamin A (Lmna) transcript variant 3, (10ug) |
USD 660.00 |
|
MR227597L3 | Lenti ORF clone of Lmna (Myc-DDK-tagged) - Mouse lamin A (Lmna), transcript variant 3 |
USD 800.00 |
|
MR227597L4 | Lenti ORF clone of Lmna (mGFP-tagged) - Mouse lamin A (Lmna), transcript variant 3 |
USD 800.00 |
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