Crem (NM_001271503) Mouse Tagged ORF Clone

CAT#: MR228979

Crem (myc-DDK-tagged) - Mouse cAMP responsive element modulator (Crem), transcript variant 12

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Crem
• Synonyms: ICER; ICERI
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR228979 representing NM_001271503
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGCAAATGTGGCAGGAAAAAGTATATGAGGACAAATGTAAGGCAAATGACCATGGAAACAGTTGAAT
  CACAGCAGGATCGAAGTGTAACACGTTCTGTGGCAGAGCATAGCTCTGCTCATATGCAGACTGGTCAAAT
  TTCTGTTCCTACTCTAGCTCAGGTTTCTGTAGCTGGATCAGGCACTGGAAGAGGCTCCCCAGCTGTGACT
  CTAGTACAGTTACCTTCAGGCCAAACTGTACAGGTCCAGGGAGTTATTCAGACACCACATCCATCGGTTA
  TTCAATCACCACAAATACAAACTGTTCAGGTAGCAACAATTGCAGAGACAGATGATTCTGCAGACTCAGA
  AGTAATTGATTCGCATAAACGTAGAGAAATTCTTTCACGAAGACCCTCATATAGAAAAATACTGAATGAA
  CTTTCCTCTGATGTGCCTGGTATTCCCAAGATTGAAGAAGAAAAATCAGAGGAAGAAGGGACACCACCTA
  ACATTGCTACCATGGCAGTACCAACTAGCATATATCAGACTAGCACGGGGCAATACACTGCCACAGGTGA
  CATGCCAACTTACCAGATCCGAGCTCCTACTACTGCTTTGCCACAAGGTGTGGTGATGGCTGCCTCACCA
  GGAAGCCTGCACAGTCCCCAGCAACTAGCAGAAGAAGCAACTCGCAAGCGGGAGCTGAGGCTGATGAAAA
  ACAGGGAAGCTGCTAAAGAATGTCGACGTCGAAAGAAAGAGTATGTGAAGTGTCTTGAGAGTCGAGTCGC
  AGTGCTGGAAGTTCAGAACAAGAAGCTTATAGAGGAGCTTGAAACTTTGAAAGACATTTGCTCTCCCAAA
  ACAGAT
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR228979 representing NM_001271503
  Red=Cloning site Green=Tags(s)
  
  MSKCGRKKYMRTNVRQMTMETVESQQDRSVTRSVAEHSSAHMQTGQISVPTLAQVSVAGSGTGRGSPAVT
  LVQLPSGQTVQVQGVIQTPHPSVIQSPQIQTVQVATIAETDDSADSEVIDSHKRREILSRRPSYRKILNE
  LSSDVPGIPKIEEEKSEEEGTPPNIATMAVPTSIYQTSTGQYTATGDMPTYQIRAPTTALPQGVVMAASP
  GSLHSPQQLAEEATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPK
  TD
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001271503
• ORF Size: 846 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001271503.1, NP_001258432.1
• RefSeq Size: 2137
• RefSeq ORF: 849
• Locus ID: 12916
• MW: 31.5 kDa
• Gene Summary: This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as either activators or repressors of transcription. Activity of this gene is important in multiple developmental processes, including spermatogenesis. Mutation of this gene causes male infertility. Alternative splicing and promoter usage result in multiple transcript variants for this gene. [provided by RefSeq, Oct 2012]