Arntl2 (NM_001289681) Mouse Tagged ORF Clone

CAT#: MR229456

Arntl2 (myc-DDK-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator-like 2 (Arntl2), transcript variant 4

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Arntl2
• Synonyms: 4632430A05Rik; bHLHe6; BMAL2; CLIF; MOP9
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >MR229456 representing NM_001289681
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGAGCTGTACCGTCCCTGTCAAAGAAGAGCAGCCATGCTCGTCCTGCTCAAAGAAGAAAGACCATA
  GAAAATTCCACACCGTCCATTGCACTGGATACTTGAGAAGCTGGCCTCTGAATGTTGTTGGCATGGAGAA
  AGAGTCGGGTGGTGGGAAGGACAGCGGTCCTCTTACCTGCCTTGTGGCTATGGGACGGTTGCATCCATAC
  ATTGTCCCTCAAAAGAGTGGCAAGATCAACGTGAGACCGGCTGAGTTCATAACTCGCTTCGCAATGAACG
  GGAAATTCGTCTATGTTGACCAAAGGGCAACGGCAATTTTAGGATACCTGCCTCAGGAACTTTTGGGAAC
  TTCATGTTATGAATATTTTCATCAGGATGACCACAGTAGTTTGACTGACAAGCACAAAGCAGTTCTGCAG
  AGTAAGGAGAAAATACTTACAGACTCATACAAATTCAGAGTGAAGGATGGTGCCTTCGTGACTCTGAAGA
  GTGAGTGGTTCAGCTTCACAAACCCTTGGACCAAAGAGCTGGAGTACATTGTGTCTGTCAACACATTGGT
  TTTGGGGCGCAGTGAGACCAGGCTGTCTTTGCTTCATTGCGGCGGCAGCAGCCAGTCCTCCGAAGACTCA
  TTTAGACAATCCTGCATCAATGTGCCCGGTGTATCCACGGGGACCGTCCTTGGTGCTGGGAGTATTGGAA
  CAGATATTGCAAATGAGGTTCTGAGTTTACAGAGATTACACTCTTCATCCCCAGAAGATGCAAGCCCTTC
  AGAAGAAGTGAGAGATGACTGCAGTGTAAATGGTGGGAATGCCTATGGGCCTGCATCCACTAGGGAGCCT
  TTTGCAGTGAGCCCTTCTGAAACAGAGGTCCTGGAGGCTGCCAGGCAACACCAGAGCACTGAACCCGCCC
  ACCCTCACGGACCACTTCCCGGTGACAGTGCCCAGCTGGGTTTTGATGTCCTGTGTGACAGTGACAGCAT
  AGACATGGCTGCATTCATGAATTACCTCGAAGCAGAGGGGGGCCTGGGTGACCCTGGGGACTTCAGTGAC
  ATCCAGTGGGCACTC
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >MR229456 representing NM_001289681
  Red=Cloning site Green=Tags(s)
  
  MKSCTVPVKEEQPCSSCSKKKDHRKFHTVHCTGYLRSWPLNVVGMEKESGGGKDSGPLTCLVAMGRLHPY
  IVPQKSGKINVRPAEFITRFAMNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHSSLTDKHKAVLQ
  SKEKILTDSYKFRVKDGAFVTLKSEWFSFTNPWTKELEYIVSVNTLVLGRSETRLSLLHCGGSSQSSEDS
  FRQSCINVPGVSTGTVLGAGSIGTDIANEVLSLQRLHSSSPEDASPSEEVRDDCSVNGGNAYGPASTREP
  FAVSPSETEVLEAARQHQSTEPAHPHGPLPGDSAQLGFDVLCDSDSIDMAAFMNYLEAEGGLGDPGDFSD
  IQWAL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001289681
• ORF Size: 1065 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001289681.1, NP_001276610.1
• RefSeq Size: 2547
• RefSeq ORF: 1068
• Locus ID: 272322
• MW: 39.2 kDa
• Gene Summary: This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (Per, Arnt, Sim) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian Clock protein, the structurally related Mop4, and hypoxia-inducible factors, such as Hif1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]